69 Best Pharma Startups to Watch in 2025

The Definitive Seedtable Ranking of Pharma Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 1,485 start-ups with an aggregate funding of $10.5b. The average funding per company in this subset is $152.9m.

Last update to the database: Feb 18, 2025. See changelog.

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15

Funding Rounds

$140.4m

Money raised

Synthace is a software company based out of London, UK, building automation software that gives biologists the ability to control and analyze the performance of lab hardware.

1

Funding Rounds

$50.0k

Money raised

Pembient uses advances in biotechnology to fabricate horn and other wildlife products to combat the threat to endangered species.

5

Funding Rounds

$236.7m

Money raised

A genetic medicine company that build data platforms using synthetic biology, artificial intelligence and genetic medicine for the development of medical therapies.

Key people:

8

Funding Rounds

$406.4m

Money raised

Bolt Threads is a biotechnology company that makes high performance fabrics and materials using biology.

5

Funding Rounds

$5.1m

Money raised

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

Location:

Key people:

7

Funding Rounds

$254.1m

Money raised

Owkin is a medical treatment and therapeutics company founded by Thomas Clozel. They develop artificial intelligence and machine learning tools to augment and develop medical and biological research.

Location:

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6

Funding Rounds

$356.3m

Money raised

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

Location:

Key people:

7

Funding Rounds

$83.0m

Money raised

Molecular Assemblies, Inc. is an enzymatic DNA synthesis technology founded in 2013 by Curt Becker, Bill Efcavitch and William Efcavitch.

1

Funding Rounds

$25.3m

Money raised

Leo Cancer Care is a company developing upright radiotherapy solutions.

4

Funding Rounds

$1.8b

Money raised

Grail is a biotechnology company headquartered in Menlo Park, California that was founded as a spinoff of Illumina Inc and initially headed by Jeffrey Huber in 2016, focused on making a medical device that can detect early stage cancer.

5

Funding Rounds

$76.5m

Money raised

A clinical-stage biopharmaceutical company engaging in drug discovery and drug development for treating autoimmune disease and cancer.

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

10

Funding Rounds

$635.4m

Money raised

Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.

Location:

Key people:

2

Funding Rounds

$16.8m

Money raised

Orbit Discovery offers a DNA-encoded peptide display technology to identify potential peptide drugs for a range of chronic diseases.

Industries:

Key people:

6

Funding Rounds

$83.3m

Money raised

BenchSci is a biotechnology company with a machine learning platform for researching biological compounds. It was founded in 2015 and is located in Toronto, Canada.

Location:

Key people:

4

Funding Rounds

$49.6m

Money raised

Inato matches the right sites to the right clinical research study, globally.

Location:

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5

Funding Rounds

$218.1m

Money raised

HistoSonics is a venture-backed medical device start-up company developing a non-invasive sonic beam therapy platform and procedure using the science of histotripsy. Histotripsy utilizes the pressure created by focused sound energy to liquify and destroy targeted tissue, including diseased tissue and tumors, at sub-cellular levels.

10

Funding Rounds

$410.0m

Money raised

Paige provides AI-based digital diagnostics and a vendor-neutral platform designed to drive diagnostic confidence and a more productive pathology workflow.

13

Funding Rounds

$386.6m

Money raised

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

3

Funding Rounds

$21.5m

Money raised

RoosterBio is a biotechnology company located in Frederick, Maryland, founded by Jon Rowley in 2013 providing standardized stem cell products for R&D, clinical, and commercial use in the regenerative medicine industry.

11

Funding Rounds

$50.0m

Money raised

An industrial biotech company developing a commercial bioprocess for manufacturing bio-based malonic acid.

6

Funding Rounds

$88.0m

Money raised

Prellis Biologics is developing technology to build transplantable human organs and tissues.

Location:

Key people:

1

Funding Rounds

$24.1m

Money raised

Neos Therapeutics is a pharmaceutical company developing ADHD medications founded in 2008.

3

Funding Rounds

$145.0m

Money raised

Cala Health offers bioelectronic medicines, medical devices, and neurotherapeutics for managing chronic health conditions.

Key people:

6

Funding Rounds

$190.5m

Money raised

Kuur Therapeutics focuses on the development of CAR-NKT cell therapies platform for applications in cancer treatment.

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

5

Funding Rounds

$103.1m

Money raised

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

9

Funding Rounds

$82.6m

Money raised

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

Location:

Key people:

6

Funding Rounds

$15.8m

Money raised

Massive Bio is a New York-based company founded by Selin Kurnaz, Dr. Arturo Loaiza-Bonilla and Cagatay M. Culcuoglu, offering precision oncology services to cancer patients, providers, and pharmaceutical companies.

2

Funding Rounds

$13.8m

Money raised

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

3

Funding Rounds

$32.0m

Money raised

miRagen is a clinical stage biopharmaceutical company developing innovative microRNA-targeting therapies to improve human health.

Key people:

6

Funding Rounds

$4.6m

Money raised

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

6

Funding Rounds

$86.6m

Money raised

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

Location:

Key people:

3

Funding Rounds

$54.1k

Money raised

ApexQubit is a biotechnology company that is harnessing a proprietary technology for discovery of new medicines to treat patients with undruggable diseases.

14

Funding Rounds

$87.2m

Money raised

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

Location:

Key people:

3

Funding Rounds

$143.4m

Money raised

An exosome therapeutics company founded in 2016 and based in Oxford, UK, that uses exosomes to deliver small and large molecule therapeutics. The company has a proprietary technology to modify exosomes to target specific organs such as the brain and central nervous system.

Key people:

5

Funding Rounds

$57.1m

Money raised

Metabolon is a company developing metabolomics analytical methods and software for biomarker discovery

2

Funding Rounds

$4.5m

Money raised

Cellink AB is a biotechnology research company based in Gothenburg.

6

Funding Rounds

$265.4m

Money raised

A New Zealand industrial biotechnology company developing a gas fermentation platform for converting concentrated industrial emissions into valuable chemicals.

8

Funding Rounds

$92.7m

Money raised

Develops medicines for patients suffering from Alzheimer's disease and other neurological disorders.

8

Funding Rounds

$41.9m

Money raised

Onfleet is a company that manages last mile deliveries using routing, dispatching and real-time tracking software.

Location:

Key people:

3

Funding Rounds

$280.0m

Money raised

A therapeutics company founded in 2016 working in drug discovery and development using fungi. LifeMine uses genomics approaches to search for biosynthetic genes in eukaryotic microbes for the discovery of naturally inspired drugs to treat previously untreatable and significant chronic diseases.

Key people:

2

Funding Rounds

$50.3m

Money raised

Lung Therapeutics is a therapeutics for lung injury and disease company founded in 2013 by Andrew Mazar, Steven Idell and Sreerama Shetty.

2

Funding Rounds

$18.1m

Money raised

A biotechnology company that develops treatments for cancer and hematologic conditions

1

Funding Rounds

$73.0m

Money raised

Antheia is an American biotechnology company founded in 2013, and is located in Menlo Park, California. Antheia uses synthetic biology, informatics, and fermentation technologies to produce plant based medicines; most notably opioids using yeast.

10

Funding Rounds

$187.8m

Money raised

Causaly is a biomedical research discovery tool founded in 2018 by Yiannis Kiachopoulos.

Location:

Key people:

5

Funding Rounds

$26.8m

Money raised

A biotechnology company developing live attenuated vaccines. It was founded in 2012 and is located in New York.

6

Funding Rounds

$230.6m

Money raised

Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.

Key people:

Dharmacon, Inc. is a Lafayette, Colorado-based company founded in 1995.

7

Funding Rounds

$268.8m

Money raised

TruePill is a US-based company providing pharmacy product deliveries.

2

Funding Rounds

$120.0k

Money raised

Avro is a life sciences company, located in Canada and founded in 2016 by Shakir Lakhani and Keean Waterloo, Ontario, that makes skin patches capable of delivering generic drugs.

Location:

Key people:

3

Funding Rounds

$52.0m

Money raised

3T Biosciences is a biotechnology company developing immunotherapies.

3

Funding Rounds

$39.9m

Money raised

Rodin Therapeutics was a biotechnology company that developed treatments for Alzheimer's disease. Founded in 2013, it was acquired in 2019 by Alkermes.

Key people:

1

Funding Rounds

Roquette is a French company focused on the production of plant-based food and nutrition ingredients for the food, beverage and pharmaceutical industries. The company was founded in 1933 by Dominique & Germain Roquette, and is headquartered in Lestrem, Nord-Pas-De-Calais, France.

1

Funding Rounds

$10.5m

Money raised

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

4

Funding Rounds

$479.5m

Money raised

Formerly BioMedicines, Intarcia Therapeutics is an American biopharmaceutical company developing therapies for diseases with long-term treatment requirements.

5

Funding Rounds

$82.8m

Money raised

Peptome is a London-based protein physics intelligence company founded in 2016 by Kamil Tamiola and Matt Heberling. It utilizes artificial intelligence for computers to process all information about protein data in the same efficient way that scientists do.

Location:

Key people:

5

Funding Rounds

$425.0m

Money raised

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

1

Funding Rounds

$1.2m

Money raised

Bond Pet Foods is a biotechnology company located in Nederland, Colorado, founded in 2015 by Rich Kelleman. Bond Pet Foods is making "cruelty free" real animal protein pet foods using cellular agriculture.

2

Funding Rounds

$55.0m

Money raised

Palvella Therapeutics is committed to developing safe and effective therapies that specifically target the root cause of genetic skin diseases.

Key people:

7

Funding Rounds

$31.4m

Money raised

Oxford Genetics, also known as Oxgene, is a synthetic biology company specializing in DNA design, protein expression optimization and cell line development technologies and services.

4

Funding Rounds

$205.5m

Money raised

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

13

Funding Rounds

$677.0m

Money raised

A gene editing technology company founded in 2015 and based in Boulder, CO, USA.

2

Funding Rounds

$11.5m

Money raised

An artificial intelligence company with a focus on developing solutions for the healthcare industry. It was founded in 2017 and is located in Tel Aviv, Israel.

Industries:

Location:

Key people:

4

Funding Rounds

$46.7m

Money raised

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

Location:

Key people:

2

Funding Rounds

$645.0k

Money raised

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

4

Funding Rounds

$96.5m

Money raised

Foundation Medicine is a Cambridge, Massachusetts-based pharmaceutical company developing diagnostic and treatment solutions for cancer care founded in 2010 by Alexis Borisy.

Key people:

3

Funding Rounds

$117.5m

Money raised

A biopharmaceutical company focused on developing treatments for urea cycle disorders and other rare diseases

Key people:

2

Funding Rounds

$30.0m

Money raised

Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.

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