69 Best Application Programming Interface Api Startups to Watch in 2025

The Definitive Seedtable Ranking of Application Programming Interface Api Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 369 start-ups with an aggregate funding of $11.3b. The average funding per company in this subset is $163.5m.

Last update to the database: Feb 18, 2025. See changelog.

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ClimaCell logo

ClimaCell

ClimaCell is a Boston-based weather intelligence platform for automated weather predictions.

6

Funding Rounds

$95.0m

Money raised

Sisense logo

Sisense

Sisense is a software company offering a platform for data analysts and data engineers to transform data into actionable business insights.

8

Funding Rounds

$274.7m

Money raised

Hasura logo

Hasura

Hasura is a software and development tools company, offering tools for developers to simplify application development.

5

Funding Rounds

$241.5m

Money raised

Zapier logo

Zapier

Zapier is an American for-profit corporation and a web-based service that allows end users to integrate the web applications they use.

1

Funding Rounds

$1.2m

Money raised

42Crunch logo

42Crunch

42Crunch is an enterprise API security platform with integrated services, including an API firewall, to discover and remediate API security vulnerabilities.

5

Funding Rounds

$37.7m

Money raised

Auth0 logo

Auth0

Auth0 is an authentication and authorization service for application developers.

9

Funding Rounds

$332.3m

Money raised

Postman logo

Postman

Postman is a San Francisco-based software company offering an API development environment.

5

Funding Rounds

$433.0m

Money raised

Unifonic logo

Unifonic

Unifonic is a Saudi-based cloud communication startup.

2

Funding Rounds

$146.0m

Money raised

Plivo logo

Plivo

Plivo is a cloud-based communications platform as a service (CPaaS) company headquartered in San Francisco, California. The company allows software developers to integrate phone calls, text messages, and other communication functions into their applications using its web service APIs.

2

Funding Rounds

$2.0m

Money raised

Contentful logo

Contentful

Contentful's platform helps teams deliver digital experiences faster with an API-first approach.

20

Funding Rounds

$363.4m

Money raised

Fortress Identity logo

Fortress Identity

Fortress Identity is a Miami-based cybersecurity developer offering multi-factor authentication with biometrics inherence factors to secure iOS and Android applications, active directory environments and Citrix applications.

2

Funding Rounds

$3.0m

Money raised

PolyAI logo

PolyAI

PolyAI is a company building an enterprise conversational platform with AI-generated voice assistants to improve customer experience.

4

Funding Rounds

$68.4m

Money raised

Strapi logo

Strapi

Strapi is a company offering an open-source headless content management system (CMS).

5

Funding Rounds

$90.0m

Money raised

Algolia logo

Algolia

Algolia is a company designing and building search and discovery API for websites and mobile apps. It participated in the W14 cohort of Y Combinator.

9

Funding Rounds

$462.2m

Money raised

MuleSoft logo

MuleSoft

A technology company, now part of Salesforce, providing an integration platform for connecting SaaS & enterprise applications.

7

Funding Rounds

$259.0m

Money raised

Replit logo

Replit

Replit is a San Francisco-based IDE and software development environment company making a browser application platform for coding in over fifty programming languages.

7

Funding Rounds

$207.3m

Money raised

EVEN Financial logo

EVEN Financial

EVEN Financial offers a B2B2C API to help connect financial institutions to consumers, and connect consumers to personalized financial products.

3

Funding Rounds

$46.8m

Money raised

SendBird logo

SendBird

SendBird is a developer of a messaging API for mobile applications and websites.

7

Funding Rounds

$218.1m

Money raised

Salt Security logo

Salt Security

Salt Security is a Palo Alto, California-based protection platform for APIs and associated API integrations.

7

Funding Rounds

$281.0m

Money raised

Stardust logo

Stardust

Stardust is a company that develops solutions for gaming in the metaverse.

2

Funding Rounds

$35.0m

Money raised

Directly logo

Directly

Directly is a San Francisco-based developer of artificial intelligence systems of customer experience and chatbots founded by Antony Brydon, Jean Tessier and Jeff Patterson.

7

Funding Rounds

$97.8m

Money raised

Crunchbase logo

Crunchbase

Crunchbase is company that offers an online platform for discovering information related to private and public businesses.

6

Funding Rounds

$276.5m

Money raised

MachineMetrics logo

MachineMetrics

MachineMetrics is a developer of industrial IoT analytics and a machine monitoring platform.

6

Funding Rounds

$37.7m

Money raised

Flatiron Health logo

Flatiron Health

Flatiron Health is a startup that organizes real-time oncology data to help cancer patients and doctors.

3

Funding Rounds

$313.0m

Money raised

Onfido logo

Onfido

Onfido is an identity verification service for enterprises.

7

Funding Rounds

$309.9m

Money raised

Symbl.ai logo

Symbl.ai

Symbl is an API platform for businesses looking to deploy conversational intelligence.

6

Funding Rounds

$23.7m

Money raised

RapidAPI logo

RapidAPI

Rapid API is a software company specializing in developing a platform for application programming interfaces.

7

Funding Rounds

$272.5m

Money raised

Segment (company) logo

Segment (company)

Segment is a company providing a data infrastructure for businesses.

3

Funding Rounds

$239.6m

Money raised

Railsr logo

Railsr

Railsr, formerly Railsbank, is a London-based open-API banking and compliance platform that gives regulated and un-regulated companies access to global bankings.

4

Funding Rounds

$118.2m

Money raised

MonkeyLearn logo

MonkeyLearn

MonkeyLearn is an artificial intelligence data analysis and visualization platform.

4

Funding Rounds

$3.2m

Money raised

Kairos (company) logo

Kairos (company)

Facial recognition company Kairos today announced the alpha release of the Kairos Protocol, a biometric verification system for cryptocurrency transactions.

6

Funding Rounds

$9.8m

Money raised

Corsha logo

Corsha

Corsha provides API security software that aims to prevent network attacks through multi-factor authentication for APIs.

3

Funding Rounds

$13.9m

Money raised

Sano Intelligence logo

Sano Intelligence

Sano is a technology company making a biometric sensor that provides users with information about how their body metabolizes glucose. Sano Intelligence was acquired by One Drop in April 2020.

3

Funding Rounds

$14.3m

Money raised

Noname Security logo

Noname Security

Noname Security is a Palo Alto, California-based cybersecurity and network security company developing products to protect APIs.

3

Funding Rounds

$220.0m

Money raised

Nylas logo

Nylas

A company offering a communications platform allows developers to quickly build features that connect to every email, calendar, and contacts provider in the world.

5

Funding Rounds

$162.5m

Money raised

SickWeather logo

SickWeather

An app that aggregates social media data to produce a real-time map of sickness.

5

Funding Rounds

$2.3m

Money raised

Uphold logo

Uphold

Uphold (formerly Bitreserve) is a cloud-based digital money platform. Users can buy, hold, convert and transact across currencies and commodities, including cryptocurrencies.

1

Funding Rounds

$8.0m

Money raised

AssemblyAI logo

AssemblyAI

AssemblyAI is a speech AI company developing AI models capable of transcribing and understanding human speech.

5

Funding Rounds

$108.1m

Money raised

Spire Health logo

Spire Health

Spire is a company developing tags that provide health tracking including respiration, sleep, stress, activity, and pulse rate.

5

Funding Rounds

$48.1m

Money raised

Gupshup logo

Gupshup

Gupshup is an AI-powered messaging platform that integrates with communication software and protocols for commerce, marketing, and support applications.

5

Funding Rounds

$373.0m

Money raised

Kong (company) logo

Kong (company)

Kong (formerly Mashape) is a San Francisco-based company that offers open source microservice API gateway.

5

Funding Rounds

$167.6m

Money raised

DrChrono logo

DrChrono

DrChrono is a company providing EHR, Practice Management, and Revenue Cycle Management Solution APIs. It participated in the W11 cohort of Y Combinator.

9

Funding Rounds

$57.5m

Money raised

Practice Fusion logo

Practice Fusion

Practice Fusion is a San Francisco-based developer of electronic health record and medical practice management software.

8

Funding Rounds

$132.0m

Money raised

Sinch logo

Sinch

Sinch offers programmable SMS, voice, video, and verification tools.

6

Funding Rounds

$2.8b

Money raised

Cardiogram (company) logo

Cardiogram (company)

Cardiogram is a company building a personal healthcare assistant, using Deep Learning to turn consumer wearables into continuous health monitors. Cariogram can now detect 4 medical conditions Sleep Apnea, High Blood Pressure, Atrial Fibrillation, and Diabetes.

1

Funding Rounds

$2.0m

Money raised

StopLight logo

StopLight

Stoplight is an Austin, Texas based company developing an API design and documentation platform.

4

Funding Rounds

$20.4m

Money raised

GYANT logo

GYANT

A patient connection and relationship management company, using artificial intelligence-enabled technology to drive more meaningful patient-doctor engagements while improving care utilization and pathways.

2

Funding Rounds

$20.4m

Money raised

Fullcontact logo

Fullcontact

A company building an identity resolution & insights platform

5

Funding Rounds

$33.9m

Money raised

Jaspersoft logo

Jaspersoft

A software platform for data visualization and embedding reports & dashboards.

4

Funding Rounds

$43.5m

Money raised

Keen logo

Keen

Keen is a company founded in 2011 by Kyle Wild, Ryan Spraetz and Dan Kador.

3

Funding Rounds

$15.6m

Money raised

AppDirect logo

AppDirect

AppDirect is a company providing an end-to-end cloud commerce platform for businesses.

7

Funding Rounds

$430.8m

Money raised

Sanity logo

Sanity

Sanity is a software company offering a customizable headless content management system (HCMS).

7

Funding Rounds

$86.8m

Money raised

PubNub logo

PubNub

U.S-based company providing cloud infrastructure for global software and hardware development and deployment.

7

Funding Rounds

$134.0m

Money raised

Moesif logo

Moesif

Moesif is a Caifornia-based company providing API analytics and tools.

2

Funding Rounds

$15.5m

Money raised

Firebase logo

Firebase

Firebase is a mobile and web application development platform. It was founded in 2011 and acquired by Google in 2014. It is located in San Francisco, California.

1

Funding Rounds

$5.6m

Money raised

SmartBear Software logo

SmartBear Software

SmartBear Software is a company developing tools for various software development and API management tasks.

3

Funding Rounds

$25.0m

Money raised

TruePill logo

TruePill

TruePill is a US-based company providing pharmacy product deliveries.

7

Funding Rounds

$268.8m

Money raised

BloomAPI logo

BloomAPI

Bloom API is a healthcare company focused on communication practices.

1

Funding Rounds

$2.4m

Money raised

Lithic logo

Lithic

Lithic is a financial technology company that builds payments infrastructure for businesses and consumers.

4

Funding Rounds

$115.4m

Money raised

Traceable logo

Traceable

Traceable is an API security software developed to protect application infrastructures.

2

Funding Rounds

$80.0m

Money raised

PokitDok logo

PokitDok

An insurance technology company offering a platform for healthcare organizations to access health insurance data to improve their ability to bring new products and services to market.

3

Funding Rounds

$5.3m

Money raised

Mailjet logo

Mailjet

Mailjet is an email services provider.

6

Funding Rounds

$17.6m

Money raised

Speechly logo

Speechly

Speechly is a Helsinki-based developer of a voice interface API for web and mobile applications.

3

Funding Rounds

$2.9m

Money raised

NewsWhip logo

NewsWhip

NewsWhip is a predictive media monitoring tool founded in 2011 by Paul Quigley.

7

Funding Rounds

$35.3m

Money raised

FalconX logo

FalconX

FalconX is a blockchain, cryptocurrency, and fintech-focused brokerage and digital asset trading platform.

8

Funding Rounds

$327.0m

Money raised

Coterie (company) logo

Coterie (company)

Coterie is an API-based commercial business insurance provider that updates policy changes in real-time.

4

Funding Rounds

$70.0m

Money raised

Pliant logo

Pliant

Pliant is a company offering a workflow orchestration and infrastructure automation platform.

6

Funding Rounds

$42.3m

Money raised

BetterDoctor logo

BetterDoctor

BetterDoctor, a technology company, delivers provider directory data and has a database that can be accessed through a responsive API.

5

Funding Rounds

$24.1m

Money raised

Lob (company) logo

Lob (company)

Lob is a company developing and building APIs for automating mail and customer communications with print media. It participated in the S13 cohort of Y Combinator.

7

Funding Rounds

$99.4m

Money raised