69 Best Immunotherapy Startups to Watch in 2025

The Definitive Seedtable Ranking of Immunotherapy Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 313 start-ups with an aggregate funding of $6.3b. The average funding per company in this subset is $91.5m.

Last update to the database: Feb 18, 2025. See changelog.

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OncoImmune logo

OncoImmune

A clinical-stage biopharmaceutical company engaging in drug discovery and drug development for treating autoimmune disease and cancer.

5

Funding Rounds

$76.5m

Money raised

Senti Biosciences logo

Senti Biosciences

Senti Biosciences is a synthetic biology company.

2

Funding Rounds

$158.0m

Money raised

BlueRock Therapeutics logo

BlueRock Therapeutics

A biotechnology company developing engineered cell therapies for treating diseases in neurology, cardiology and autoimmunity.

1

Funding Rounds

$225.0m

Money raised

Orig3n logo

Orig3n

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

5

Funding Rounds

$111.8m

Money raised

Kuur Therapeutics logo

Kuur Therapeutics

Kuur Therapeutics focuses on the development of CAR-NKT cell therapies platform for applications in cancer treatment.

6

Funding Rounds

$190.5m

Money raised

Locus Biosciences logo

Locus Biosciences

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

8

Funding Rounds

$117.5m

Money raised

Promethera Biosciences logo

Promethera Biosciences

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

5

Funding Rounds

$103.1m

Money raised

ViaCyte logo

ViaCyte

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

16

Funding Rounds

$328.8m

Money raised

Cell Design Labs logo

Cell Design Labs

A biotechnology company founded in 2015 which operates as a subsidiary of Gilead Sciences and Kite Pharma. The company developed a platform for custom cell engineering called synNotch to be used for anticancer therapies. Their system can also be used to develop cell-based therapies for autoimmune and degenerative disorders.

1

Funding Rounds

$34.4m

Money raised

Stemline Therapeutics logo

Stemline Therapeutics

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

2

Funding Rounds

$13.8m

Money raised

EpiBone logo

EpiBone

EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.

1

Funding Rounds

Prokarium logo

Prokarium

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

6

Funding Rounds

$86.6m

Money raised

Cellink AB (publ) logo

Cellink AB (publ)

Cellink AB is a biotechnology research company based in Gothenburg.

2

Funding Rounds

$4.5m

Money raised

EdiGene logo

EdiGene

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

9

Funding Rounds

$262.0m

Money raised

Obsidian Therapeutics logo

Obsidian Therapeutics

Develops novel cell and gene therapies with pharmacologic operating systems.

2

Funding Rounds

$164.5m

Money raised

Argos Therapeutics logo

Argos Therapeutics

A company developing immunotherapy treatments for cancers, infectious and autoimmune diseases

2

Funding Rounds

$67.5m

Money raised

Cellerant Therapeutics logo

Cellerant Therapeutics

A biotechnology company that develops treatments for cancer and hematologic conditions

2

Funding Rounds

$18.1m

Money raised

Insitro logo

Insitro

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

4

Funding Rounds

$743.2m

Money raised

3T Biosciences logo

3T Biosciences

3T Biosciences is a biotechnology company developing immunotherapies.

3

Funding Rounds

$52.0m

Money raised

Betalin Therapeutics logo

Betalin Therapeutics

Biological micro-pancreas for insulin-dependent diabetics company

4

Funding Rounds

$5.1m

Money raised

Integrated DNA Technologies logo

Integrated DNA Technologies

Integrated DNA Technologies is a Coralville, Iowa-based company founded in 1987.

1

Funding Rounds

Bit.bio logo

Bit.bio

Bit.bio is a biotechnology company that aims to operate within human cells through means of coding and biology.

3

Funding Rounds

$183.9m

Money raised

Tmunity Therapeutics logo

Tmunity Therapeutics

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

5

Funding Rounds

$425.0m

Money raised

Juventus Therapeutics logo

Juventus Therapeutics

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

4

Funding Rounds

$46.7m

Money raised

Odyssey Therapeutics logo

Odyssey Therapeutics

Focused on transforming lives of patients with immune dysfunctions and cancer

2

Funding Rounds

$386.0m

Money raised

Encellin logo

Encellin

Encellin is a biotechnology company developing diabetes therapeutics using insulin responsive cells.

1

Funding Rounds

$5.9m

Money raised

Celdara Medical logo

Celdara Medical

Celdara Medical is a biotechnology company helping turn academic innovations into medical products.

1

Funding Rounds

$1.7m

Money raised

DCPrime logo

DCPrime

DCPrime is a biotechnology company developing cancer immunotherapies.

5

Funding Rounds

$26.0m

Money raised

iOx Therapeutics Limited logo

iOx Therapeutics Limited

Biotechnology company founded in 2015 that develops and commercializes synthetic lipid compounds and cancer immunotherapy agents. iOx Therapeutics is an OSI spinout.

1

Funding Rounds

resTORbio logo

resTORbio

A biopharmaceutical company developing therapeutics for treating age-related diseases.

3

Funding Rounds

$105.0m

Money raised

Eureka Therapeutics, Inc logo

Eureka Therapeutics, Inc

Eureka Therapeutics is a biotechnology company developing immunotherapies for the treatment of cancer.

2

Funding Rounds

$105.0m

Money raised

Immunomic Therapeutics logo

Immunomic Therapeutics

A biotechnology company developing nucleic acid immunotherapy platform and protein based vaccines

2

Funding Rounds

$60.6m

Money raised

Kiadis Pharma logo

Kiadis Pharma

Kiadis Pharma is a biotechnology company developing stem cell regenerative medicine treatments for blood cancers and blood disorders.

1

Funding Rounds

$12.8m

Money raised

Novadip Biosciences logo

Novadip Biosciences

Novadip Biosciences is a biotechnology company developing regenerative medicines using stem cells.

2

Funding Rounds

$82.0m

Money raised

Tessa Therapeutics logo

Tessa Therapeutics

A biotechnology company developing t-cell immunotherapies therapies for the treatment of cancer. The company is headquartered in Singapore, and was founded by Malcolm Brenner and Andrew Khoo in 2011.

1

Funding Rounds

$80.0m

Money raised

GentiBio logo

GentiBio

GentiBio, Inc. is a biotherapeutics company developing engineered regulatory T cells (Tregs) therapies for immunology.

2

Funding Rounds

$177.0m

Money raised

Gadeta logo

Gadeta

Gadeta is a biotechnology company developing immunotherapies for treating cancer.

1

Funding Rounds

$7.0m

Money raised

Soteria Biotherapeutics logo

Soteria Biotherapeutics

Soteria Biotherapeutics is a biotechnology company developing cancer immunotherapies.

1

Funding Rounds

$42.2m

Money raised

Kyverna Therapeutics logo

Kyverna Therapeutics

Kyverna is a cell therapy company engineering a new class of curative living medicines for inflammatory and autoimmune diseases.

2

Funding Rounds

$110.0m

Money raised

Ossium Health logo

Ossium Health

Ossium is building the world's first bone marrow bank to treat blood cancers, improve organ transplantation, and repair damage

3

Funding Rounds

$73.4m

Money raised

Immusoft logo

Immusoft

Immusoft is a biotechnology company developing a platform for the insertion of therapeutic genes into immune cells for the treatment of a variety of genetic diseases.

11

Funding Rounds

$37.9m

Money raised

Locate Bio logo

Locate Bio

Locate Bio is a biotechnology developing cell and gene therapies for treating damaged tissues and organs.

9

Funding Rounds

$59.1m

Money raised

Trailhead Biosystems logo

Trailhead Biosystems

Trailhead Biosystems is a biotechnology company developing cell therapy products.

3

Funding Rounds

$17.2m

Money raised

IRX Therapeutics logo

IRX Therapeutics

A company developing immune therapies for cancer and related diseases

2

Funding Rounds

$33.8m

Money raised

STEMCELL Technologies logo

STEMCELL Technologies

A Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research.

1

Funding Rounds

$15.0m

Money raised

Gradalis logo

Gradalis

Gradalis is a drug manufacturer, and developer of vaccines, tools and diagnostics for the treatment of cancer.

1

Funding Rounds

$24.0m

Money raised

Abcuro, Inc. logo

Abcuro, Inc.

Abcuro develops immunotherapies to treat autoimmunity and cancer.

4

Funding Rounds

$72.3m

Money raised

Carisma Therapeutics logo

Carisma Therapeutics

Carisma Therapeutics is a biotechnology company founded in 2016 to bring the potheyr of adoptive cellular immunotherapy to solid tumor patients through a novel platform using chimeric antigen receptor macrophages (CARMA).

2

Funding Rounds

$112.0m

Money raised

Refuge Biotechnologies logo

Refuge Biotechnologies

Refuge Biotechnologies is a biotechnology company that uses CRISPR and cell therapy technologies for treating cancer.

2

Funding Rounds

$33.9m

Money raised

XEME Biopharma logo

XEME Biopharma

XEME Biopharma is a biotechnology company developing therapeutic cancer vaccines and cancer immunotherapy products.

2

Funding Rounds

$173.0k

Money raised

American Gene Technologies logo

American Gene Technologies

AGT is developing and commercializing gene and cell therapy and targeting major diseases, including HIV/AIDS, Phenylketonuria (PKU) and Hepatocellular carcinoma.

4

Funding Rounds

$6.0m

Money raised

A2 Biotherapeutics, Inc logo

A2 Biotherapeutics, Inc

A2 Biotherapeutics, Inc. is a biotechnology research company developing T-cell therapies designed to attack solid tumors while sparing normal cells

1

Funding Rounds

$71.5m

Money raised

TeVideo Biodevices logo

TeVideo Biodevices

TeVido Biodevices is a biotechnology company developing cell therapy products for restoring lost skin pigment.

4

Funding Rounds

$1.4m

Money raised

PACT Pharma logo

PACT Pharma

PACT Pharma is synthesizing neo-epitope targeted T cells and producing a personalized adoptive cell therapy designed to benefit each cancer patient.

3

Funding Rounds

$200.0m

Money raised

StemBioSys logo

StemBioSys

StemBioSys is a biotechnology company developing regenerative medicines using stem cells.

1

Funding Rounds

$1.5m

Money raised

Mogrify logo

Mogrify

Mogrify is developing tailored cellular conversions that power future cell therapies.

8

Funding Rounds

$84.5m

Money raised

Biosceptre logo

Biosceptre

Biosceptre is a Cambridge, Cambridgeshire-based company developing diagnostic tools and biomarkers.

3

Funding Rounds

$13.2m

Money raised

Tactiva Therapeutics logo

Tactiva Therapeutics

Tactiva Therapeutics is a biotechnology company developing cancer immunotherapies.

1

Funding Rounds

$35.0m

Money raised

Stemedica Cell Technologies logo

Stemedica Cell Technologies

Stemedica Cell Technologies is a biopharmaceutical company developing and manufacturing adult stem cells and stem cell factors for research institutions and hospitals for pre-clinical and clinical studies

1

Funding Rounds

$22.0m

Money raised

Encoded Therapeutics, Inc. logo

Encoded Therapeutics, Inc.

Encoded Therapeutics is a developer of genomics-driven precision medicine targeting and treating genetic diseases and disorders.

4

Funding Rounds

$343.1m

Money raised

Pandion Therapeutics logo

Pandion Therapeutics

Pandion Therapeutics is a Cambridge, Massachusetts-based company developing modular proteins, antibodies and bispecifics for autoimmune and inflammatory diseases.

3

Funding Rounds

$138.0m

Money raised

Cytonus Therapeutics logo

Cytonus Therapeutics

Cytonus Therapeutics is a biotechnology company developing adaptive cellular therapies for treating immune-oncology and inflammatory diseases.

4

Funding Rounds

$2.6m

Money raised

Amunix Pharmaceuticals, Inc. logo

Amunix Pharmaceuticals, Inc.

Amunix is an immuno-oncology company focused on developing immune-activating biotherapeutics for patients with solid tumor cancers.

4

Funding Rounds

$193.3m

Money raised

Universal Cells logo

Universal Cells

Universal Cells is a biotechnology company developing regenerative medicine using stem cells.

1

Funding Rounds

$60.0k

Money raised

Qihan Biotech logo

Qihan Biotech

Qihan Biotech is a hangzhou-based biotech company focused on organ transplantation founded in 2017 by Luhan Yang.

1

Funding Rounds

$67.0m

Money raised

Anagenesis Biotechnologies logo

Anagenesis Biotechnologies

Anagenesis Biotechnologies is a biotechnology company developing pre-clinical stem cell therapies for treating genetic and age-related muscle degenerative diseases.

1

Funding Rounds

$3.4m

Money raised

Targazyme logo

Targazyme

Targazyme is a biotechnology company focused on improving survival and quality of life for cancer patients using stem cell transplantation, immunotherapy, regenerative medicine, and gene therapy.

1

Funding Rounds

$2.5m

Money raised

Macomics Ltd logo

Macomics Ltd

Macomics is an Edinburgh-based immuno-oncology company.

2

Funding Rounds

$10.0m

Money raised

Aspect Biosystems logo

Aspect Biosystems

Aspect Biosystems is a 3D bioprinting founded in 2013 by Tamer Mohamed, Konrad Walus, Sam Wadsworth and Simon Beyer.

1

Funding Rounds

$20.0m

Money raised