69 Best Immunotherapy Startups to Watch in 2025

The Definitive Seedtable Ranking of Immunotherapy Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 309 start-ups with an aggregate funding of $6.3b. The average funding per company in this subset is $91.9m.

Last update to the database: Feb 18, 2025. See changelog.

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5

Funding Rounds

$5.1m

Money raised

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

Location:

Key people:

5

Funding Rounds

$76.5m

Money raised

A clinical-stage biopharmaceutical company engaging in drug discovery and drug development for treating autoimmune disease and cancer.

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

5

Funding Rounds

$111.8m

Money raised

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

6

Funding Rounds

$190.5m

Money raised

Kuur Therapeutics focuses on the development of CAR-NKT cell therapies platform for applications in cancer treatment.

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

5

Funding Rounds

$103.1m

Money raised

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

16

Funding Rounds

$328.8m

Money raised

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

2

Funding Rounds

$13.8m

Money raised

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

1

Funding Rounds

EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.

6

Funding Rounds

$86.6m

Money raised

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

Location:

Key people:

2

Funding Rounds

$4.5m

Money raised

Cellink AB is a biotechnology research company based in Gothenburg.

9

Funding Rounds

$262.0m

Money raised

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

2

Funding Rounds

$164.5m

Money raised

Develops novel cell and gene therapies with pharmacologic operating systems.

2

Funding Rounds

$67.5m

Money raised

A company developing immunotherapy treatments for cancers, infectious and autoimmune diseases

2

Funding Rounds

$18.1m

Money raised

A biotechnology company that develops treatments for cancer and hematologic conditions

4

Funding Rounds

$743.2m

Money raised

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

3

Funding Rounds

$52.0m

Money raised

3T Biosciences is a biotechnology company developing immunotherapies.

3

Funding Rounds

$183.9m

Money raised

Bit.bio is a biotechnology company that aims to operate within human cells through means of coding and biology.

4

Funding Rounds

$5.1m

Money raised

Biological micro-pancreas for insulin-dependent diabetics company

5

Funding Rounds

$425.0m

Money raised

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

4

Funding Rounds

$46.7m

Money raised

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

Location:

Key people:

2

Funding Rounds

$386.0m

Money raised

Focused on transforming lives of patients with immune dysfunctions and cancer

1

Funding Rounds

$5.9m

Money raised

Encellin is a biotechnology company developing diabetes therapeutics using insulin responsive cells.

Key people:

1

Funding Rounds

$1.7m

Money raised

Celdara Medical is a biotechnology company helping turn academic innovations into medical products.

Key people:

5

Funding Rounds

$26.0m

Money raised

DCPrime is a biotechnology company developing cancer immunotherapies.

1

Funding Rounds

Biotechnology company founded in 2015 that develops and commercializes synthetic lipid compounds and cancer immunotherapy agents. iOx Therapeutics is an OSI spinout.

Location:

Key people:

3

Funding Rounds

$105.0m

Money raised

A biopharmaceutical company developing therapeutics for treating age-related diseases.

2

Funding Rounds

$105.0m

Money raised

Eureka Therapeutics is a biotechnology company developing immunotherapies for the treatment of cancer.

2

Funding Rounds

$60.6m

Money raised

A biotechnology company developing nucleic acid immunotherapy platform and protein based vaccines

1

Funding Rounds

$12.8m

Money raised

Kiadis Pharma is a biotechnology company developing stem cell regenerative medicine treatments for blood cancers and blood disorders.

2

Funding Rounds

$82.0m

Money raised

Novadip Biosciences is a biotechnology company developing regenerative medicines using stem cells.

Location:

Key people:

1

Funding Rounds

$80.0m

Money raised

A biotechnology company developing t-cell immunotherapies therapies for the treatment of cancer. The company is headquartered in Singapore, and was founded by Malcolm Brenner and Andrew Khoo in 2011.

2

Funding Rounds

$177.0m

Money raised

GentiBio, Inc. is a biotherapeutics company developing engineered regulatory T cells (Tregs) therapies for immunology.

1

Funding Rounds

$7.0m

Money raised

Gadeta is a biotechnology company developing immunotherapies for treating cancer.

1

Funding Rounds

$42.2m

Money raised

Soteria Biotherapeutics is a biotechnology company developing cancer immunotherapies.

2

Funding Rounds

$110.0m

Money raised

Kyverna is a cell therapy company engineering a new class of curative living medicines for inflammatory and autoimmune diseases.

3

Funding Rounds

$73.4m

Money raised

Ossium is building the world's first bone marrow bank to treat blood cancers, improve organ transplantation, and repair damage

Location:

Key people:

11

Funding Rounds

$37.9m

Money raised

Immusoft is a biotechnology company developing a platform for the insertion of therapeutic genes into immune cells for the treatment of a variety of genetic diseases.

Location:

Key people:

9

Funding Rounds

$59.1m

Money raised

Locate Bio is a biotechnology developing cell and gene therapies for treating damaged tissues and organs.

3

Funding Rounds

$17.2m

Money raised

Trailhead Biosystems is a biotechnology company developing cell therapy products.

2

Funding Rounds

$33.8m

Money raised

A company developing immune therapies for cancer and related diseases

1

Funding Rounds

$15.0m

Money raised

A Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research.

1

Funding Rounds

$24.0m

Money raised

Gradalis is a drug manufacturer, and developer of vaccines, tools and diagnostics for the treatment of cancer.

4

Funding Rounds

$72.3m

Money raised

Abcuro develops immunotherapies to treat autoimmunity and cancer.

2

Funding Rounds

$112.0m

Money raised

Carisma Therapeutics is a biotechnology company founded in 2016 to bring the potheyr of adoptive cellular immunotherapy to solid tumor patients through a novel platform using chimeric antigen receptor macrophages (CARMA).

2

Funding Rounds

$33.9m

Money raised

Refuge Biotechnologies is a biotechnology company that uses CRISPR and cell therapy technologies for treating cancer.

Key people:

2

Funding Rounds

$173.0k

Money raised

XEME Biopharma is a biotechnology company developing therapeutic cancer vaccines and cancer immunotherapy products.

4

Funding Rounds

$6.0m

Money raised

AGT is developing and commercializing gene and cell therapy and targeting major diseases, including HIV/AIDS, Phenylketonuria (PKU) and Hepatocellular carcinoma.

1

Funding Rounds

$71.5m

Money raised

A2 Biotherapeutics, Inc. is a biotechnology research company developing T-cell therapies designed to attack solid tumors while sparing normal cells

Key people:

4

Funding Rounds

$1.4m

Money raised

TeVido Biodevices is a biotechnology company developing cell therapy products for restoring lost skin pigment.

3

Funding Rounds

$200.0m

Money raised

PACT Pharma is synthesizing neo-epitope targeted T cells and producing a personalized adoptive cell therapy designed to benefit each cancer patient.

1

Funding Rounds

$1.5m

Money raised

StemBioSys is a biotechnology company developing regenerative medicines using stem cells.

8

Funding Rounds

$84.5m

Money raised

Mogrify is developing tailored cellular conversions that power future cell therapies.

3

Funding Rounds

$13.2m

Money raised

Biosceptre is a Cambridge, Cambridgeshire-based company developing diagnostic tools and biomarkers.

1

Funding Rounds

$35.0m

Money raised

Tactiva Therapeutics is a biotechnology company developing cancer immunotherapies.

Key people:

1

Funding Rounds

$22.0m

Money raised

Stemedica Cell Technologies is a biopharmaceutical company developing and manufacturing adult stem cells and stem cell factors for research institutions and hospitals for pre-clinical and clinical studies

6

Funding Rounds

$37.4m

Money raised

Developer of vaccines to provide broad-spectrum protection against highly mutating respiratory viruses.

Location:

Key people:

4

Funding Rounds

$343.1m

Money raised

Encoded Therapeutics is a developer of genomics-driven precision medicine targeting and treating genetic diseases and disorders.

3

Funding Rounds

$138.0m

Money raised

Pandion Therapeutics is a Cambridge, Massachusetts-based company developing modular proteins, antibodies and bispecifics for autoimmune and inflammatory diseases.

4

Funding Rounds

$2.6m

Money raised

Cytonus Therapeutics is a biotechnology company developing adaptive cellular therapies for treating immune-oncology and inflammatory diseases.

4

Funding Rounds

$193.3m

Money raised

Amunix is an immuno-oncology company focused on developing immune-activating biotherapeutics for patients with solid tumor cancers.

1

Funding Rounds

$60.0k

Money raised

Universal Cells is a biotechnology company developing regenerative medicine using stem cells.

1

Funding Rounds

$67.0m

Money raised

Qihan Biotech is a hangzhou-based biotech company focused on organ transplantation founded in 2017 by Luhan Yang.

Location:

Key people:

1

Funding Rounds

$3.4m

Money raised

Anagenesis Biotechnologies is a biotechnology company developing pre-clinical stem cell therapies for treating genetic and age-related muscle degenerative diseases.

1

Funding Rounds

$2.5m

Money raised

Targazyme is a biotechnology company focused on improving survival and quality of life for cancer patients using stem cell transplantation, immunotherapy, regenerative medicine, and gene therapy.

2

Funding Rounds

$10.0m

Money raised

Macomics is an Edinburgh-based immuno-oncology company.

Key people:

1

Funding Rounds

$20.0m

Money raised

Aspect Biosystems is a 3D bioprinting founded in 2013 by Tamer Mohamed, Konrad Walus, Sam Wadsworth and Simon Beyer.

Key people:

4

Funding Rounds

$241.9m

Money raised

Asklepios Biopharmaceutical is a company in North Carolina.

Key people:

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