We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.
There are 408 start-ups with an aggregate funding of $8.5b. The average funding per company in this subset is $122.5m.
Last update to the database: Feb 18, 2025. See changelog.
Bolt Threads is a biotechnology company that makes high performance fabrics and materials using biology.
8
Funding Rounds
$406.4m
Money raised
Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases
6
Funding Rounds
$356.3m
Money raised
Notable Labs is a company providing personalized drug combination testing service for cancer patients.
8
Funding Rounds
$71.3m
Money raised
Senti Biosciences is a synthetic biology company.
2
Funding Rounds
$158.0m
Money raised
Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.
6
Funding Rounds
$399.8m
Money raised
Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.
10
Funding Rounds
$635.4m
Money raised
Orbit Discovery offers a DNA-encoded peptide display technology to identify potential peptide drugs for a range of chronic diseases.
2
Funding Rounds
$16.8m
Money raised
A company developing antibody-based biological medicines for kidney diseases and other chronic diseases. Visterra was acquired by Otsuka Pharmaceutical in 2018.
4
Funding Rounds
$153.7m
Money raised
A biotechnology company developing engineered cell therapies for treating diseases in neurology, cardiology and autoimmunity.
1
Funding Rounds
$225.0m
Money raised
A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.
13
Funding Rounds
$386.6m
Money raised
An industrial biotech company developing a commercial bioprocess for manufacturing bio-based malonic acid.
11
Funding Rounds
$50.0m
Money raised
Scribe Therapeutics develops molecular engineering solutions for CRISPR-based genetic medicine.
2
Funding Rounds
$120.0m
Money raised
Neos Therapeutics is a pharmaceutical company developing ADHD medications founded in 2008.
1
Funding Rounds
$24.1m
Money raised
AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.
5
Funding Rounds
$68.7m
Money raised
Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.
8
Funding Rounds
$117.5m
Money raised
Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.
9
Funding Rounds
$82.6m
Money raised
A biotechnology company founded in 2015 which operates as a subsidiary of Gilead Sciences and Kite Pharma. The company developed a platform for custom cell engineering called synNotch to be used for anticancer therapies. Their system can also be used to develop cell-based therapies for autoimmune and degenerative disorders.
1
Funding Rounds
$34.4m
Money raised
A biopharmaceutical company developing therapeutics to attack cancer stem cells.
2
Funding Rounds
$13.8m
Money raised
miRagen is a clinical stage biopharmaceutical company developing innovative microRNA-targeting therapies to improve human health.
3
Funding Rounds
$32.0m
Money raised
A company developing anti-aging treatments using components derived from human blood.
3
Funding Rounds
$41.0m
Money raised
EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.
1
Funding Rounds
ApexQubit is a biotechnology company that is harnessing a proprietary technology for discovery of new medicines to treat patients with undruggable diseases.
3
Funding Rounds
$54.1k
Money raised
An exosome therapeutics company founded in 2016 and based in Oxford, UK, that uses exosomes to deliver small and large molecule therapeutics. The company has a proprietary technology to modify exosomes to target specific organs such as the brain and central nervous system.
3
Funding Rounds
$143.4m
Money raised
Emerald Therapeutics is a biotechnology company located in San Fransisco, California, founded by Brian Frezza and DJ Klienbaum in 2010. Emerald Therapeutics offers cloud a based software and hardware platform that allows researchers to remotely perform automated scientific laboratory experiments.
2
Funding Rounds
$22.8m
Money raised
A New Zealand industrial biotechnology company developing a gas fermentation platform for converting concentrated industrial emissions into valuable chemicals.
6
Funding Rounds
$265.4m
Money raised
Envisagenics is a biotechnology company founded by Maria Luisa Pineda and Martin Akerman in 2014 and headquartered in New York City, New York using artificial intelligence and RNA sequencing to develop therapeutics to treat genetic diseases.
9
Funding Rounds
$26.8m
Money raised
Develops medicines for patients suffering from Alzheimer's disease and other neurological disorders.
8
Funding Rounds
$92.7m
Money raised
Develops novel cell and gene therapies with pharmacologic operating systems.
2
Funding Rounds
$164.5m
Money raised
A company developing immunotherapy treatments for cancers, infectious and autoimmune diseases
2
Funding Rounds
$67.5m
Money raised
A therapeutics company founded in 2016 working in drug discovery and development using fungi. LifeMine uses genomics approaches to search for biosynthetic genes in eukaryotic microbes for the discovery of naturally inspired drugs to treat previously untreatable and significant chronic diseases.
3
Funding Rounds
$280.0m
Money raised
Lung Therapeutics is a therapeutics for lung injury and disease company founded in 2013 by Andrew Mazar, Steven Idell and Sreerama Shetty.
2
Funding Rounds
$50.3m
Money raised
A biotechnology company that develops treatments for cancer and hematologic conditions
2
Funding Rounds
$18.1m
Money raised
A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.
4
Funding Rounds
$743.2m
Money raised
Ichor Therapeutics is a pre-clinical contract research on aging mechanisms company founded in 2013 by Kelsey Moody.
5
Funding Rounds
$2.5m
Money raised
Nextbiotics is a biotechnology and synthetic biology company that leverages synthetic biology tools and bacteriophage technology to provide solutions to the antibiotic resistance crisis.
1
Funding Rounds
$750.0k
Money raised
Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.
6
Funding Rounds
$230.6m
Money raised
Rodin Therapeutics was a biotechnology company that developed treatments for Alzheimer's disease. Founded in 2013, it was acquired in 2019 by Alkermes.
3
Funding Rounds
$39.9m
Money raised
Biological micro-pancreas for insulin-dependent diabetics company
4
Funding Rounds
$5.1m
Money raised
Oisin develops anti-aging treatments that target and remove senescent cells, a type of damaged cell that is unable to divide, accumulates during aging and contribute to age-related diseases.
4
Funding Rounds
$7.1m
Money raised
Dyno Therapeutics is a company based in Cambridge, Massachusetts applying artificial intelligence to gene therapy, focused on adeno-associated virus capsid engineering.
3
Funding Rounds
$109.0m
Money raised
Antera Therapeutics is an allergy prevention development company.
2
Funding Rounds
$2.0m
Money raised
SWORD Health is a digital therapy provider for pain.
12
Funding Rounds
$576.4m
Money raised
ImStar Therapeutics is company developing treatments for ALS, dementia, and other neurodegenerative diseases.
1
Funding Rounds
$1.8m
Money raised
Peptome is a London-based protein physics intelligence company founded in 2016 by Kamil Tamiola and Matt Heberling. It utilizes artificial intelligence for computers to process all information about protein data in the same efficient way that scientists do.
5
Funding Rounds
$82.8m
Money raised
Faeth Therapeutics is a start-up that focuses on using nutrition and metabolism to fight cancer.
3
Funding Rounds
$67.0m
Money raised
Palvella Therapeutics is committed to developing safe and effective therapies that specifically target the root cause of genetic skin diseases.
2
Funding Rounds
$55.0m
Money raised
Aegle Therapeutics Corporation, a regenerative medicine company isolating extracellular vesicles ("EVs") from allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat severe dermatological conditions, including burns and epidermolysis bullosa (“EB”).
5
Funding Rounds
$14.5m
Money raised
A biotechnology company using mass spectrometry platforms for drug discovery and the development of therapeutics.
1
Funding Rounds
$100.0m
Money raised
Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.
4
Funding Rounds
$46.7m
Money raised
CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.
2
Funding Rounds
$645.0k
Money raised
YourChoice Therapeutics is a biotechnology company founded in 2018 is developing contraceptives for men and women. The technology for their non-hormonal contraceptive products arose from research at the University of California, Berkeley.
4
Funding Rounds
$16.8m
Money raised
Biofourmis is a global health IT start-up in Massachusetts that focuses on personalized care and therapies using digital therapeutics.
7
Funding Rounds
$443.5m
Money raised
A biopharmaceutical company focused on developing treatments for urea cycle disorders and other rare diseases
3
Funding Rounds
$117.5m
Money raised
Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.
2
Funding Rounds
$30.0m
Money raised
Translate Bio is a clinical-stage mRNA therapeutics company developing medicines to treat diseases caused by protein or gene dysfunction and vaccines against infectious disease pathogens.
6
Funding Rounds
$227.7m
Money raised
OncoSenX is a spinout company of Oisin Biotechnologies, formed to develop programmable suicide gene therapy to kill cancerous cells.
5
Funding Rounds
$19.7m
Money raised
Synthetic biology company that created novel DNA base pairs and uses them to incorporate novel amino acids into proteins for potential therapeutics in areas of cancer and autoimmune disorders.
5
Funding Rounds
$152.0m
Money raised
Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.
3
Funding Rounds
$59.2m
Money raised
ITM Isotopen Technologien Munchen is a Munich-based developer of personalized cancer diagnostic solutions.
2
Funding Rounds
$58.4m
Money raised
Focused on transforming lives of patients with immune dysfunctions and cancer
2
Funding Rounds
$386.0m
Money raised
Rheostat, located at 300 Technology Square, in Cambridge, Massachusetts is a biotech company developing treatments for neurodegenerative diseases by targeting mitophagy and autophagy pathways.
2
Funding Rounds
$46.0m
Money raised
Oraya Therapeutics is a biotechnology company developing non-invasive therapies for eye diseases that is headquartered in San Francisco, California and was founded in 2007 by Michael Gertner.
3
Funding Rounds
$64.0m
Money raised
Genecentric Diagnostics, Inc. is an oncology diagnostic and treatment center.
4
Funding Rounds
$13.9m
Money raised
Cerecin, formerly Accera, is a company that looks to develop therapeutic drugs for neurodegenerative diseases.
7
Funding Rounds
$189.5m
Money raised
Synthetic biology company developing vaccines and therapeutics using cell-free biology technology
2
Funding Rounds
$10.5m
Money raised
Stelvio Therapeutics is a biotechnology company developing therapeutics for cancer.
1
Funding Rounds
A biotechnology company founded in 2013 that develops technology to treat heart disease using pluripotent stem cells. Disease in a dish and clinical trial in a dish platforms are used to develop cardiovascular drugs and perform cardio-toxicity safety testing for non-cardiovascular drugs.
1
Funding Rounds
$5.5m
Money raised
Leucadia Therapeutics is a company working on Alzheimer's Disease.
1
Funding Rounds
A bio-data company that uses AI to analyze RNA sequencing data
2
Funding Rounds
$5.4m
Money raised