51 Best Chemistry Startups to Watch in 2025

The Definitive Seedtable Ranking of Chemistry Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 51 start-ups with an aggregate funding of $4.0b. The average funding per company in this subset is $77.7m.

Last update to the database: Feb 18, 2025. See changelog.

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Arzeda logo

Arzeda

Arzeda is a biotechnology and software company designing custom microorganisms for industrial applications through computational enzyme design, protein optimization, and metabolic engineering.

5

Funding Rounds

$72.2m

Money raised

Rigetti Computing logo

Rigetti Computing

Rigetti Computing is a quantum computing company based in Berkeley, California.

10

Funding Rounds

$269.5m

Money raised

Insilico Medicine logo

Insilico Medicine

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

6

Funding Rounds

$356.3m

Money raised

Molecular Assemblies, Inc. logo

Molecular Assemblies, Inc.

Molecular Assemblies, Inc. is an enzymatic DNA synthesis technology founded in 2013 by Curt Becker, Bill Efcavitch and William Efcavitch.

7

Funding Rounds

$83.0m

Money raised

Solugen logo

Solugen

Solugen is a speciality chemical manufacturing company developing aiming to replace petroleum-based chemicals with alternatives made from plant-based substitutes.

9

Funding Rounds

$474.1m

Money raised

Metabolon logo

Metabolon

Metabolon is a company developing metabolomics analytical methods and software for biomarker discovery

5

Funding Rounds

$57.1m

Money raised

Zapata Computing logo

Zapata Computing

Zapata Computing is a company developing quantum software and algorithms for business founded in 2017 by Christopher Savoie, Alán Aspuru-Guzik, Jhonathan Romero Fontalvo, Jonathan Olson, Peter Johnson and Yudong Cao.

6

Funding Rounds

$107.6m

Money raised

Ansa Biotechnologies logo

Ansa Biotechnologies

DNA synthesis company using enzymatic DNA synthesis based in San Francisco.

4

Funding Rounds

$87.8m

Money raised

Oxford Drug Design Limited logo

Oxford Drug Design Limited

Oxford Drug Design Limited is a company that focuses on developing and delivering services and technologies for computer-aided drug discovery

5

Funding Rounds

$10.0m

Money raised

Genapsys logo

Genapsys

Genapsys is a company developing DNA sequencing technologies and systems founded in 2010 by Hesaam Esfandyarpour.

10

Funding Rounds

$402.1m

Money raised

Nanome logo

Nanome

Nanome is a company developing software for life sciences, materials sciences and nano-engineering with the use of virtual reality and blockchain technology.

4

Funding Rounds

$6.4m

Money raised

TFF Pharmaceuticals logo

TFF Pharmaceuticals

TFF Pharmaceuticals is a dry-powder Inhalation for Respiratory Therapies founded in 2018.

2

Funding Rounds

$22.2m

Money raised

Redesign Science Inc logo

Redesign Science Inc

Redesign Science Inc is a computational chemistry company that is interested in small molecule drug discovery

2

Funding Rounds

$7.4m

Money raised

Qu & Co logo

Qu & Co

Qu & Co is a company that offers quantum-computational chemistry as-a-service.

2

Funding Rounds

Crown Bioscience logo

Crown Bioscience

Crown bioscience is a company that is focused on research, drug discovery and development for the treatment of cancer and diabetes.

6

Funding Rounds

$62.1m

Money raised

Southern Research logo

Southern Research

A non-profit organization with a focus on scientific and engineering research. It was founded in 1941 and is located in Birmingham, Alabama.

2

Funding Rounds

$8.7m

Money raised

Pili logo

Pili

Pili is a biotechnology company using microorganisms fed sugar to synthesize commercial quality dyes.

9

Funding Rounds

$40.9m

Money raised

Biocrates Life Sciences AG logo

Biocrates Life Sciences AG

Biocrates Life Sciences AG is an Innsbruck-based medical diagnostics company focused on metabolomic research and technology.

8

Funding Rounds

$13.6m

Money raised

AM Pharma logo

AM Pharma

AM-Pharma is a biopharmaceutical company developing recombinant human Alkaline Phosphatase (AP) therapeutics, which have the potential to treat patients with Acute Kidney Injury, Inflammatory Bowel Disease and Hypophosphatasia.

3

Funding Rounds

$302.8m

Money raised

ReviveMed logo

ReviveMed

ReviveMed is a biotech start-up that analyses metabolomic data using artificial intelligence, which allows them to design new medical therapeutics.

2

Funding Rounds

$1.5m

Money raised

OyaGen logo

OyaGen

OyaGen is an HIV Drug Discovery, Editing Enzymes founded in 2003 by Harold Smith.

5

Funding Rounds

$6.6m

Money raised

QunaSys logo

QunaSys

QunaSys is a Bunkyo, Tokyo-based information technology company.

3

Funding Rounds

$2.8m

Money raised

Almac logo

Almac

Almac is a biomedical services company based in the UK founded in 1968 by Allen McClay.

2

Funding Rounds

$1.4m

Money raised

Abzena logo

Abzena

A company that provides services and technologies for the development and commercialization of biopharmaceutical products

2

Funding Rounds

$20.0m

Money raised

Storm Therapeutics logo

Storm Therapeutics

Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer

4

Funding Rounds

$101.6m

Money raised

Nimbus Therapeutics logo

Nimbus Therapeutics

Nimbus Therapeutics is a Computer-Based Drug Discovery founded in 2011 by Bruce Booth.

4

Funding Rounds

$53.0m

Money raised

Sygnature Discovery Limited logo

Sygnature Discovery Limited

Sygnature Discovery Limited is a drug Discovery Contract Research founded in 2004 by Simon Hirst.

1

Funding Rounds

Lyndra Therapeutics (company) logo

Lyndra Therapeutics (company)

Lyndra Therapeutics is a drug Delivery founded in 2015.

3

Funding Rounds

$143.0m

Money raised

Encodia Inc. logo

Encodia Inc.

Encodia Inc. is a protein Analysis Technologies founded in 2015.

1

Funding Rounds

$75.0m

Money raised

Nitrase Therapeutics logo

Nitrase Therapeutics

Nitrase Therapeutics is a Brisbane, California-based company offering a biopharmaceutical platform, Nitrome, designed to offer therapies against a broad variety of diseases.

1

Funding Rounds

$83.0m

Money raised

HelixBind logo

HelixBind

HelixBind is a Marlborough, Massachusetts-based medical diagnostics company developing diagnostic platforms for invasive infections founded in 2012 by Alon Singer.

1

Funding Rounds

$1.7m

Money raised

Cirius Therapeutics logo

Cirius Therapeutics

Cirius Therapeutics is a company developing an insulin sensitizer for the treatment of non-alcoholic steatohepatitis.

1

Funding Rounds

$40.0m

Money raised

Enzymatics logo

Enzymatics

Enzymatics is a Beverly, Massachusetts-based biological products customizing company.

1

Funding Rounds

$3.8m

Money raised

Apostle Inc logo

Apostle Inc

Apostle Inc is a Sunnyvale, California-based company providing technologies and services for public health and life sciences.

2

Funding Rounds

$5.7m

Money raised

Element Biosciences logo

Element Biosciences

Element Biosciences is a genetic analysis tools.

2

Funding Rounds

$291.0m

Money raised

Sagimet Biosciences Inc. logo

Sagimet Biosciences Inc.

Sagimet Biosciences Inc. is a drugs targeting the fatty acid synthase enzyme.

3

Funding Rounds

$185.0m

Money raised

SFA Therapeutics logo

SFA Therapeutics

SFA Therapeutics is a microbiome-derived metabolites as drugs founded in 2016 by Ira Spector, Mark Feitelson and Alla Arzumanyan.

1

Funding Rounds

$4.0m

Money raised

BioHybrid Solutions logo

BioHybrid Solutions

BioHybrid Solutions is a company founded by Krzysztof Matyjaszewski, Alan Russell and Antonina Simakova.

1

Funding Rounds

Poxel logo

Poxel

Poxel is a biopharmaceutical company developing drugs for metabolic diseases founded in 2009.

1

Funding Rounds

$20.3m

Money raised

Debut Biotechnology logo

Debut Biotechnology

Debut Biotechnology is a Cell-Free Biomanufacturing.

2

Funding Rounds

$25.2m

Money raised

Exo Therapeutics logo

Exo Therapeutics

Exo Therapeutics is a small Molecule Drug Discovery.

1

Funding Rounds

$78.0m

Money raised

reMYND logo

reMYND

reMYND is a preclinical In-Vivo Alzheimer's Contract Research.

1

Funding Rounds

$14.5m

Money raised

Molecule.one logo

Molecule.one

Molecule.one makes universal working environment software for synthetic planning chemists.

1

Funding Rounds

$4.6m

Money raised

ReadCoor logo

ReadCoor

ReadCoor is a Cambridge, Massachusetts-based company founded in 2016 by Evan Daugharthy.

3

Funding Rounds

$80.1m

Money raised

Sitryx logo

Sitryx

Developer of therapeutics for chronic autoimmune and inflammatory diseases.

2

Funding Rounds

$80.0m

Money raised

Boragen logo

Boragen

Boragen is a United States-based company.

1

Funding Rounds

$10.0m

Money raised

Oxyrane logo

Oxyrane

Oxyrane is an enzyme replacement therapies.

1

Funding Rounds

$26.5m

Money raised

EdenRoc Sciences LLC logo

EdenRoc Sciences LLC

EdenRoc Sciences LLC is a Cambridge, Massachusetts-based company founded in 2016.

7

Funding Rounds

$139.0m

Money raised

Xheme Inc. logo

Xheme Inc.

Xheme Inc. is a company founded in 2019.

2

Funding Rounds

$3.5m

Money raised

Azafaros logo

Azafaros

Azafaros is a small Molecules.

1

Funding Rounds

$27.5m

Money raised

Adlai Nortye Biopharma  logo

Adlai Nortye Biopharma

Adlai Nortye Biopharma is a China-based company.

1

Funding Rounds

$53.0m

Money raised