52 Best Genetic Engineering Startups to Watch in 2025

The Definitive Seedtable Ranking of Genetic Engineering Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 52 start-ups with an aggregate funding of $4.8b. The average funding per company in this subset is $91.5m.

Last update to the database: Feb 18, 2025. See changelog.

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5

Funding Rounds

$236.7m

Money raised

A genetic medicine company that build data platforms using synthetic biology, artificial intelligence and genetic medicine for the development of medical therapies.

Key people:

5

Funding Rounds

$5.1m

Money raised

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

Location:

Key people:

8

Funding Rounds

$459.7m

Money raised

Silicon Valley-based genetic engineering startup.

Key people:

1

Funding Rounds

$750.0k

Money raised

Nextbiotics is a biotechnology and synthetic biology company that leverages synthetic biology tools and bacteriophage technology to provide solutions to the antibiotic resistance crisis.

4

Funding Rounds

$87.8m

Money raised

DNA synthesis company using enzymatic DNA synthesis based in San Francisco.

1

Funding Rounds

$10.5m

Money raised

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

3

Funding Rounds

$109.0m

Money raised

Dyno Therapeutics is a company based in Cambridge, Massachusetts applying artificial intelligence to gene therapy, focused on adeno-associated virus capsid engineering.

Key people:

4

Funding Rounds

$46.7m

Money raised

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

Location:

Key people:

2

Funding Rounds

$645.0k

Money raised

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

5

Funding Rounds

$19.7m

Money raised

OncoSenX is a spinout company of Oisin Biotechnologies, formed to develop programmable suicide gene therapy to kill cancerous cells.

Location:

Key people:

2

Funding Rounds

$170.0m

Money raised

Agriculture company developing novel methods of pest control

Key people:

11

Funding Rounds

$37.9m

Money raised

Immusoft is a biotechnology company developing a platform for the insertion of therapeutic genes into immune cells for the treatment of a variety of genetic diseases.

Location:

Key people:

9

Funding Rounds

$59.1m

Money raised

Locate Bio is a biotechnology developing cell and gene therapies for treating damaged tissues and organs.

1

Funding Rounds

$2.0m

Money raised

A biotechnology company founded in 2006 and based in Baltimore, MD, that develops polymers to deliver DNA and RNA therapeutics.

1

Funding Rounds

$284.8m

Money raised

A life sciences and genomics organization. It was founded in 1999 and is located in Shenzhen, China.

2

Funding Rounds

$2.6m

Money raised

Precision therapeutics company developing epigenetic therapies that target arginine methylation in cancer.

Location:

Key people:

1

Funding Rounds

Biotherapeutics company focused on medicines for chronic inflammation, metabolic disease and autoimmune disease

4

Funding Rounds

$343.1m

Money raised

Encoded Therapeutics is a developer of genomics-driven precision medicine targeting and treating genetic diseases and disorders.

4

Funding Rounds

$2.6m

Money raised

Cytonus Therapeutics is a biotechnology company developing adaptive cellular therapies for treating immune-oncology and inflammatory diseases.

1

Funding Rounds

$2.5m

Money raised

Targazyme is a biotechnology company focused on improving survival and quality of life for cancer patients using stem cell transplantation, immunotherapy, regenerative medicine, and gene therapy.

2

Funding Rounds

$160.0m

Money raised

Forge is a gene therapy development engine, focused on enabling access to life changing gene therapies and helping bring them from idea into reality.

Key people:

1

Funding Rounds

$1.2m

Money raised

Brainvectis is a biotechnology company developing treatments for neurodegenerative diseases through restoring cholesterol metabolism in the brain.

6

Funding Rounds

$152.3m

Money raised

Vineti is a cloud-based cell-therapy management system founded in 2016 by Razmik Abnous.

1

Funding Rounds

$15.9m

Money raised

Calimmune is a biotechnology company developing gene and stem cell therapies for treating rare and serious diseases.

2

Funding Rounds

$213.9m

Money raised

AAVANTIBio is a biotechnology company developing gene therapies.

2

Funding Rounds

$15.0m

Money raised

iVexSol is a newly formed viral vector manufacturing company

4

Funding Rounds

$3.3m

Money raised

Girihlet provides an immune map database. Its platform aims to accelerate immune diseases discovery, monitoring and therapeutic approaches.

Key people:

3

Funding Rounds

$97.2m

Money raised

StrideBio is a Durham, North Carolina-based company.

5

Funding Rounds

$70.7m

Money raised

Apic Bio is a gene Therapy founded in 2017 by John Reilly.

Key people:

1

Funding Rounds

$2.3m

Money raised

Zbiotics is a company creating genetically engineered probiotics for consumers founded in 2016 by Zachary Abbott.

Key people:

3

Funding Rounds

$455.6m

Money raised

Kriya Therapeutics is a gene Therapy founded in 2019 by Shankar Ramaswamy, J. Fraser Wright and Roger Jeffs.

2

Funding Rounds

$695.0m

Money raised

ElevateBio is a company founded by Vikas Sinha, David Hallal and Melissa Carpenter.

3

Funding Rounds

$139.0m

Money raised

Limelight Bio is a biopharmaceutical company researching and developing novel gene therapy technologies.

2

Funding Rounds

$55.2m

Money raised

Xalud Therapeutics is a neuropathic pain therapies.

2

Funding Rounds

$7.5m

Money raised

Renova Therapeutics is a company that envisions a future where it can permanently treat chronic diseases

2

Funding Rounds

$59.7m

Money raised

Kolon TissueGene is a biotechnology company developing cell and gene therapies for treating osteoarthritis.

1

Funding Rounds

$41.0m

Money raised

Cyagen Biosciences is a Santa Clara, California-based biotechnology company providing rodent models, viral vector development, CAR design and construction, disease models, phenotype analysis, pharmacodynamic evaluations, and stem cell products for cell and gene therapy research.

2

Funding Rounds

$34.0m

Money raised

CureGenetics is a biotechnology company using CRISPR to develop cellular therapies, gene therapies, and molecular diagnostic tools.

Location:

Key people:

3

Funding Rounds

$16.1m

Money raised

Integra Therapeutics is a biotech company engineering the next generation of gene writing tools to cure genetic diseases.

1

Funding Rounds

$1.3m

Money raised

Hemera Biosciences is a treatment for dry macular degeneration company founded in 2010 by Jay S. Duker, Elias Reichel and Adam Rogers.

Key people:

2

Funding Rounds

$44.0m

Money raised

InnoSkel is a therapies for Rare Skeletal Diseases founded in 2020 by Elvire Gouze.

Location:

Key people:

2

Funding Rounds

$167.0m

Money raised

Ring Therapeutics is a multi-product platform company.

Key people:

2

Funding Rounds

$58.9m

Money raised

XyloCor Therapeutics is focused on improving the lives of people with cardiovascular disease through our commitment to advancing the science of gene therapy.

1

Funding Rounds

$16.5m

Money raised

Lysogene is a company by Karen Aiach.

Key people:

1

Funding Rounds

$52.0m

Money raised

Gene therapies developer for pediatric patients.

1

Funding Rounds

$130.0k

Money raised

Nuntius Therapeutics is a cell-specific DNA, RNA and CRISPR therapies founded in 2021 by Albert Kwok.

Location:

Key people:

$1.2m

Money raised

Eden Bio is a machine Learning to Guide Genetic Engineering founded in 2021.

1

Funding Rounds

$1.0m

Money raised

Myosana Therapeutics is a non-viral Gene Therapy founded in 2018.

1

Funding Rounds

$85.0m

Money raised

Gracell is a China-based company founded in 2017.

1

Funding Rounds

$3.3m

Money raised

Ikarovec is an ocular Gene Therapy founded in 2018.

2

Funding Rounds

$205.7m

Money raised

Gyroscope Therapeutics Ltd is a United Kingdom-based company founded in 2016.

1

Funding Rounds

$5.7m

Money raised

Zbiotics Co is a San Francisco-based company founded in 2016.

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