69 Best Startups in Boston to Watch in 2025

ClimaCell is a Boston-based weather intelligence platform for automated weather predictions.

Immuta is a Boston-based provider of a cloud-native data governance platform for organizations to automate data access control, security, and privacy compliance.

Snyk is a technology company offering a software development security platform using open-source code.

Boundless is a Seattle-based company offering immigrants tools, information, and personalized support to facilitate their immigration journey.

Circle is a peer-to-peer payments technology company that is headquartered in Boston, Massachusetts and was founded in 2013 by Jeremy Allaire and Sean Neville.

DataRobot sells a machine learning platform that helps users build and deploy accurate predictive models. The Boston-based company was founded in 2012 by Jeremy Achin.

PathAI is a Boston-based artificial intelligence company developing therapeutics and healthcare products.

Catalog is a Boston, Massachusetts-based company developing a platform for DNA-based digital data storage.

The RepTrak Company, formerly the Reputation Institute, is a Boston-based data-driven reputation analysis company founded in 1997 by Cees van Riel, Dr. Charles Fombrun, Kasper Ulf Nielsen and Nicolas Georges Trad.

EGenesis is a gene editing and genome engineering company developing human-compatible engineered organs to treat diseases

MachineMetrics is a developer of industrial IoT analytics and a machine monitoring platform.

Armored Things is a Boston-based company founded in 2017 by Julie Johnson, Chris Lord and Charles Curran.

Pison is a human performance company that optimizes cognitive and physiological capability using gesture control.

Klaviyo is a marketing automation software company which has a email software platform with SMS for ecommerce companies.

Binah.ai is a company that provides artificial intelligence-powered, video-based health and wellness monitoring.

An insurance technology company offering artificially intelligent software for insurance fraud detection and claims handling.

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

A healthcare company using artificial intelligence to help track and predict the onset of human diseases.

Zoe is a Boston and London-based company which builds software for tracking individuals' nutrition response patterns, as well as a mobile application for tracking COVID-19 symptoms.

Aiven is a company that offers a managed open-source and multi-cloud data platform.

Help Scout is a company developing a software platform for customer service.

Empatica designs and develops wearable health devices for health monitoring, treatment, and research.

Wanderu is a developer of a travel meta-search engine used to book inter-city buses and trains.

Neighborly drives investment in world-positive infrastructure projects like broadband, solar microgrids, and libraries.

Drift is a software company offering a conversational marketing platform founded in 2015 by David Cancel.

Logz.io is an AI-powered log analysis platform that offers the open-source ELK Stack as an enterprise-grade service.

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

Botkeeper combines artificial intelligence and machine learning technology with accountants to deliver a bookkeeping & pre-accounting solution to accounting firms and their clients.

A healthcare company helping patients management their health and their involvement in the healthcare system.

Cellink AB is a biotechnology research company based in Gothenburg.

Clear Ballot is a Boston-based company founded in 2009.

A brain-computer interface company building software and hardware products, neurotechnology tools that interpret human intent, measure emotion and provide telekinetic control of the digital world based on EEG signals.

Sherlock Biosciences is a Cambridge, Massachusetts-based company founded in 2019 by David R. Walt, Rahul Dhanda, Feng Zhang, Jim Collins, Deborah Hung, Jonathan Gootenberg, Omar Abudayyeh, Pardis Sabeti and Todd Golub.

Zapata Computing is a company developing quantum software and algorithms for business founded in 2017 by Christopher Savoie, Alán Aspuru-Guzik, Jhonathan Romero Fontalvo, Jonathan Olson, Peter Johnson and Yudong Cao.

Privy is a company founded in 2011 by Ben Jabbawy.

VMRay provides threat detection and analysis to enterprises.

Rasa is a company that offers a conversational AI platform for customized conversations at scale.

Embr Labs is a technology company that focuses on wellness that harnesses the power of cutting-edge technology to improve thermal comfort.

Accion Systems is a company that provides in-space propulsion systems for satellites

Cybereason is a Boston-based cybersecurity company.

Rapid7 is a Boston-based cybersecurity company providing security data and analytics solutions.

Metalenz is a fabless semiconductor company specializing in the development and manufacture of a flat lens system based on optical metasurfaces.

Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.

Pliant is a company offering a workflow orchestration and infrastructure automation platform.

U.S-based company providing a platform to match patients with the right healthcare personnel.

Antera Therapeutics is an allergy prevention development company.

Formerly BioMedicines, Intarcia Therapeutics is an American biopharmaceutical company developing therapies for diseases with long-term treatment requirements.

Insight Data Science is a Palo Alto-based education startup providing post-doctoral training programs in the big data industry.

A company that has created a software solution for businesses to monitor their security effectiveness. It was founded in 2011 and is located in Boston, Massachusetts.

Cogito is an enterprise cloud computing and software development company making software to provide AI-driven coaching to phone professionals.

exCater is a Boston, MA based online catering marketplace.

A company offering a platform for automatically building, running, and maintaining web application QA testing.

An insurance technology company offering a platform for employee benefits and insurance.

LogRocket is a front-end monitoring and product analytics platform for developers.

Aliro Technologies (Aliro), a spinout of the NarangLab at Harvard University, makes software that facilitates user access to present day quantum computers.

Coin Metrics provides network and market data and analysis for cryptocurrencies.

Rethink Robotics developed and patented Sawyer, a robot that can replace human labor where danger is likely or difficult.

Flipside Crypto is a blockchain company founded in 2017 by Dave Balter, Jim Myers and eric stone.

Fortify is a Boston-based 3D printing company that has the goal to enable fabrication of composites with optimized microstructures

Biofourmis is a global health IT start-up in Massachusetts that focuses on personalized care and therapies using digital therapeutics.

Reify Health is a company building healthcare system

Whoop is a performance optimization system for elite athletes and teams.

Foundation Devices is a technology company developing open-source hardware for Bitcoin and Web3.

Allonnia is developing a new solution intended for waste remediation and management.

Alfresco is a software company founded in 2005 by John Newton, John Newton and John Powell.

AlgoSec is a Ridgefield Park, New Jersey-based developer of network security software automating security policy management and business applications and ensuring security compliance.

Amwell is a telemedicine company.

Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.

Crayon is a Boston-based company founded in 2015 by Jonah Lopin.