69 Best Microbiome Startups to Watch in 2025

The Definitive Seedtable Ranking of Microbiome Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 93 start-ups with an aggregate funding of $5.9b. The average funding per company in this subset is $85.0m.

Last update to the database: Feb 18, 2025. See changelog.

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6

Funding Rounds

$399.8m

Money raised

Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.

Key people:

10

Funding Rounds

$635.4m

Money raised

Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.

Location:

Key people:

1

Funding Rounds

$300.0m

Money raised

BGI is a life science and genomics organization following a development model of research, production and application.

13

Funding Rounds

$386.6m

Money raised

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

5

Funding Rounds

$68.7m

Money raised

AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.

Key people:

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

10

Funding Rounds

$87.6m

Money raised

Eligo Bioscience is a developer of novel genetic medicines founded in 2014 by Timothy Lu, Xavier Duportet, Luciano Marraffini and David Bikard.

Location:

Key people:

5

Funding Rounds

$57.1m

Money raised

Metabolon is a company developing metabolomics analytical methods and software for biomarker discovery

1

Funding Rounds

$750.0k

Money raised

Nextbiotics is a biotechnology and synthetic biology company that leverages synthetic biology tools and bacteriophage technology to provide solutions to the antibiotic resistance crisis.

1

Funding Rounds

Roquette is a French company focused on the production of plant-based food and nutrition ingredients for the food, beverage and pharmaceutical industries. The company was founded in 1933 by Dominique & Germain Roquette, and is headquartered in Lestrem, Nord-Pas-De-Calais, France.

2

Funding Rounds

$645.0k

Money raised

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

2

Funding Rounds

$30.0m

Money raised

Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.

10

Funding Rounds

$62.4m

Money raised

A software solutions company providing bioinformatics solutions to life science and other sector

5

Funding Rounds

$125.0m

Money raised

Evolve Biosystems is a biotechnology company founded in 2012. The company develops microbiome-based products engineered to restore and maintain the gut microbiome.

Location:

Key people:

2

Funding Rounds

$100.0m

Money raised

Snipr Biome is a synthetic biology company using CRISPR to make products for the microbiome.

9

Funding Rounds

$56.6m

Money raised

A company based in Farmington, Connecticut, that develops skin disease treatments using microbiome science and technology.

Key people:

1

Funding Rounds

$2.5m

Money raised

BiomeSense, Inc. is a biotechnology company developing microbiome technologies for the collection, storage, and analysis of gut microbiome profiles.

Key people:

1

Funding Rounds

$400.0k

Money raised

Xycrobe Therapeutics is a biotechnology company developing microbiome-Based, biotherapeutic delivery systems.

14

Funding Rounds

$332.5m

Money raised

Enterome is a pharmaceutical company founded in 2012 by Pierre Belichard.

Location:

Key people:

2

Funding Rounds

$14.0m

Money raised

A biotechnology company using the environmental microbiome to verify the origin of goods in global supply chains.

8

Funding Rounds

$59.9m

Money raised

MaaT Pharma (Microbiota as a Therapy) is a French biotech start-up, created at the end of 2014, to treat diseases linked to imbalances in the intestinal microbiome.

7

Funding Rounds

$252.5m

Money raised

AgBiome is focused on the discovery and development of biological and trait products for crop production.

1

Funding Rounds

$12.0m

Money raised

Developing innovative therapies focused on microbiome gut-brain axis.

8

Funding Rounds

$1.2b

Money raised

Indigo is an agricultural technology company utilizing natural microbiology and digital technologies to improve farmers' profitability, environmental sustainability and consumer health.

6

Funding Rounds

$23.4m

Money raised

Biome Makers is a biotech start-up specializing in microbiome understanding to provide analysis for agricultural and industrial processes.

Key people:

1

Funding Rounds

$125.0k

Money raised

OpenBiome is a nonprofit stool bank. They provide stool preparations to clinicians for fecal microbiota transplantation.

Key people:

3

Funding Rounds

$20.8m

Money raised

Sun Genomics is a company developing personalized probiotics founded in 2016 by Sunny Jain.

Location:

Key people:

6

Funding Rounds

$116.0m

Money raised

Axial Therapeutics is a biopharmaceutical company targeting neurological disorders such as Parkinson's and Autism via gut health.

3

Funding Rounds

$67.5m

Money raised

Second Genome is a company that is developing microbiome modulators for infection, immunity and metabolic diseases.

Key people:

7

Funding Rounds

$1.4m

Money raised

Microbiome Insights is a microbiome services and bioinformatics company.

Key people:

2

Funding Rounds

$13.8m

Money raised

Animab is a Ghent-based biotechnology company developing products for livestock health.

Location:

Key people:

6

Funding Rounds

$6.3m

Money raised

A Swiss biotech company active in research and development related to breast milk.

8

Funding Rounds

$13.6m

Money raised

Biocrates Life Sciences AG is an Innsbruck-based medical diagnostics company focused on metabolomic research and technology.

2

Funding Rounds

$9.4m

Money raised

Astarte Medical Partners is a startup company headquartered in Yardley, Pennsylvania developing microbial health informatics software that helps optimize nutrition and gut health in preterm infants.

1

Funding Rounds

$2.0m

Money raised

Genetic Analysis AS is an Oslo, Norway-based microbiota research company.

1

Funding Rounds

$40.0m

Money raised

Seed Health is a company founded in 2015.

Key people:

3

Funding Rounds

$302.8m

Money raised

AM-Pharma is a biopharmaceutical company developing recombinant human Alkaline Phosphatase (AP) therapeutics, which have the potential to treat patients with Acute Kidney Injury, Inflammatory Bowel Disease and Hypophosphatasia.

4

Funding Rounds

$14.4m

Money raised

A biotechnology company offering personalized kits for treating acne based on an individuals microbiome.

Location:

Key people:

3

Funding Rounds

$7.3m

Money raised

CosmosID is a microbial genomics platform focused on characterization of microorganisms, pathogens and anti-microbial resistance for infectious disease identification, food safety inspections, pharmaceutical discovery, public health surveillance and microbiome analysis.

5

Funding Rounds

$35.1m

Money raised

GRO Biosciences was founded by Dr. George Church at the Harvard Life Lab.

Key people:

3

Funding Rounds

$2.3m

Money raised

MicroBiome Therapeutics is a New Orleans-based company founded by Dale Pfost.

1

Funding Rounds

$39.0m

Money raised

OrphoMed is a clinical-stage biotechnology company with a proprietary dimer therapeutics platform. The company is focused on developing treatments for patients with gastrointestinal disorders.

7

Funding Rounds

$90.2m

Money raised

EnteroBiotix is a fecal microbiota transplantation founded in 2017 by James McIlroy.

Location:

Key people:

1

Funding Rounds

$15.0m

Money raised

Persephone Biosciences is a company focused on microbiome therapeutics and research.

4

Funding Rounds

$1.3m

Money raised

Carbiotix is a personalized nutrition company that produces consumer gut health products and microbiome therapeutics.

3

Funding Rounds

$2.9m

Money raised

Shoreline Biome is a Farmington, CT-based biotechnology company offering kits for microbiome analysis.

Key people:

3

Funding Rounds

$63.0m

Money raised

Developer of phage technology for targeted control of bacteria.

4

Funding Rounds

$3.6m

Money raised

A company that develops a microbiome discovery platform for animal health.

2

Funding Rounds

$4.0m

Money raised

Ample is a company producing health focused meal replacements founded in 2015 by Bryan Rosenblatt, MARK DIVINE and Connor Young.

Key people:

3

Funding Rounds

$36.3m

Money raised

Rebiotix is a company that is deveoloping microbiota restoration therapy for the treatment of gastrointestinal diseases.

1

Funding Rounds

$2.3m

Money raised

Zbiotics is a company creating genetically engineered probiotics for consumers founded in 2016 by Zachary Abbott.

Key people:

2

Funding Rounds

$2.0m

Money raised

Probiotic product development biopharmaceutical company based in Gothenburg, Sweden.

1

Funding Rounds

$35.0m

Money raised

Whole Biome is a San Francisco-based microbiome diagnostics and therapeutics company.

Location:

Key people:

1

Funding Rounds

Gallinée produces probiotic skincare products for sensitive skin.

Location:

Key people:

1

Funding Rounds

$8.3m

Money raised

Exeliom is a gut microbiome modifiers founded by Benjamin Hadida, Harry Sokol, Patrick Gervais and Philippe Langella.

Key people:

2

Funding Rounds

$51.0m

Money raised

A San Diego-based company that produces endomicrobial products for animals.

Location:

Key people:

2

Funding Rounds

$3.0m

Money raised

3Bar Biologics is a microbe delivery and manufacturing company that partners with microbe discovery and commercialization companies.

2

Funding Rounds

$10.2m

Money raised

Microba Life Sciences Limited is a company founded in 2018 by Gene Tyson.

Key people:

2

Funding Rounds

$16.8m

Money raised

BCD Bioscience is a Davis, California-based biotechnology company developing ingredients for food, agriculture, and biopharmaceutical applications.

Key people:

2

Funding Rounds

$3.5m

Money raised

ClostraBio, Inc is discovering and developing new therapeutics that modulate the protective ability of the microbiome.

4

Funding Rounds

$2.1m

Money raised

PharmaBiome is a microbiome company.

Location:

Key people:

3

Funding Rounds

$48.0m

Money raised

DayTwo provides personalized nutrition and actionable insights for people to maintain normal blood sugar levels based on their microbiome.

Location:

Key people:

3

Funding Rounds

$64.7m

Money raised

Matrisys Bioscience, Inc. is a dermatology & Skin Care founded in 2015 by Richard Gallo.

1

Funding Rounds

$4.4m

Money raised

S-Biomedic brings novel therapeutic solutions to the skin microbiome. S-Biomedic uses a targeted modulation-based technology to modify the skin microbiome. This technology can be applied in both the dermatology and cosmetic industries.

6

Funding Rounds

$392.8m

Money raised

Metagenomi Technologies, LLC is a Gene-Edited Microbial Treatments founded in 2018 by Brian C Thomas.

1

Funding Rounds

$1.4m

Money raised

Thryve provides personalized probiotics and microbiome testing.

1

Funding Rounds

$8.4m

Money raised

FitBiomics is a sports biotechnology company founded in 2015 by Alex Evans, George Church, Aleksandar Kostic, Jonathan Scheiman, Carolina Barsa and Vasco Bridges.

Industries:

Key people:

2

Funding Rounds

$6.8m

Money raised

Sundose is Europe's first second-generation supplement, the composition of which is tailored to each individual on the basis of a health survey, dietary consultation and laboratory tests.

Location:

2

Funding Rounds

$11.2m

Money raised

Microcapsules and microparticles are widely used to carry, deliver and protect pharmaceutical agents in drugs, fragrances in cosmetic products, and aromas or probiotics in food.

Location:

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