69 Best Microbiome Startups to Watch in 2025

The Definitive Seedtable Ranking of Microbiome Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 99 start-ups with an aggregate funding of $5.7b. The average funding per company in this subset is $82.4m.

Last update to the database: Feb 18, 2025. See changelog.

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UBiome logo

UBiome

UBiome was a biotechnology microbial genomics company based in San Francisco.

8

Funding Rounds

$111.4m

Money raised

Human Longevity Inc. logo

Human Longevity Inc.

Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.

6

Funding Rounds

$399.8m

Money raised

Genomatica logo

Genomatica

Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.

10

Funding Rounds

$635.4m

Money raised

BGI logo

BGI

BGI is a life science and genomics organization following a development model of research, production and application.

1

Funding Rounds

$300.0m

Money raised

Vedanta Biosciences logo

Vedanta Biosciences

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

13

Funding Rounds

$386.6m

Money raised

AOBiome logo

AOBiome

AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.

5

Funding Rounds

$68.7m

Money raised

Locus Biosciences logo

Locus Biosciences

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

8

Funding Rounds

$117.5m

Money raised

Eligo Bioscience logo

Eligo Bioscience

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

9

Funding Rounds

$82.6m

Money raised

Metabolon logo

Metabolon

Metabolon is a company developing metabolomics analytical methods and software for biomarker discovery

5

Funding Rounds

$57.1m

Money raised

Nextbiotics logo

Nextbiotics

Nextbiotics is a biotechnology and synthetic biology company that leverages synthetic biology tools and bacteriophage technology to provide solutions to the antibiotic resistance crisis.

1

Funding Rounds

$750.0k

Money raised

Roquette logo

Roquette

Roquette is a French company focused on the production of plant-based food and nutrition ingredients for the food, beverage and pharmaceutical industries. The company was founded in 1933 by Dominique & Germain Roquette, and is headquartered in Lestrem, Nord-Pas-De-Calais, France.

1

Funding Rounds

CHAIN Biotechnology logo

CHAIN Biotechnology

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

2

Funding Rounds

$645.0k

Money raised

Siolta Therapeutics logo

Siolta Therapeutics

Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.

2

Funding Rounds

$30.0m

Money raised

Eagle Genomics logo

Eagle Genomics

A software solutions company providing bioinformatics solutions to life science and other sector

10

Funding Rounds

$62.4m

Money raised

Evolve Biosystems logo

Evolve Biosystems

Evolve Biosystems is a biotechnology company founded in 2012. The company develops microbiome-based products engineered to restore and maintain the gut microbiome.

5

Funding Rounds

$125.0m

Money raised

Snipr Biome logo

Snipr Biome

Snipr Biome is a synthetic biology company using CRISPR to make products for the microbiome.

2

Funding Rounds

$100.0m

Money raised

Azitra logo

Azitra

A company based in Farmington, Connecticut, that develops skin disease treatments using microbiome science and technology.

9

Funding Rounds

$56.6m

Money raised

BiomeSense, Inc. logo

BiomeSense, Inc.

BiomeSense, Inc. is a biotechnology company developing microbiome technologies for the collection, storage, and analysis of gut microbiome profiles.

1

Funding Rounds

$2.5m

Money raised

Xycrobe Therapeutics logo

Xycrobe Therapeutics

Xycrobe Therapeutics is a biotechnology company developing microbiome-Based, biotherapeutic delivery systems.

1

Funding Rounds

$400.0k

Money raised

Enterome logo

Enterome

Enterome is a pharmaceutical company founded in 2012 by Pierre Belichard.

14

Funding Rounds

$332.5m

Money raised

Phylagen logo

Phylagen

A biotechnology company using the environmental microbiome to verify the origin of goods in global supply chains.

2

Funding Rounds

$14.0m

Money raised

MaaT Pharma logo

MaaT Pharma

MaaT Pharma (Microbiota as a Therapy) is a French biotech start-up, created at the end of 2014, to treat diseases linked to imbalances in the intestinal microbiome.

8

Funding Rounds

$59.9m

Money raised

AgBiome logo

AgBiome

AgBiome is focused on the discovery and development of biological and trait products for crop production.

7

Funding Rounds

$252.5m

Money raised

Bloom Science logo

Bloom Science

Developing innovative therapies focused on microbiome gut-brain axis.

1

Funding Rounds

$12.0m

Money raised

Biome Makers logo

Biome Makers

Biome Makers is a biotech start-up specializing in microbiome understanding to provide analysis for agricultural and industrial processes.

6

Funding Rounds

$23.4m

Money raised

Indigo logo

Indigo

Indigo is an agricultural technology company utilizing natural microbiology and digital technologies to improve farmers' profitability, environmental sustainability and consumer health.

8

Funding Rounds

$1.2b

Money raised

OpenBiome logo

OpenBiome

OpenBiome is a nonprofit stool bank. They provide stool preparations to clinicians for fecal microbiota transplantation.

1

Funding Rounds

$125.0k

Money raised

Sun Genomics logo

Sun Genomics

Sun Genomics is a company developing personalized probiotics founded in 2016 by Sunny Jain.

3

Funding Rounds

$20.8m

Money raised

Naked Biome logo

Naked Biome

Naked Biome is a microbiome-based therapeutics company founded in 2015 and headquartered in San Francisco, California making therapies to treat and prevent skin diseases and conditions.

3

Funding Rounds

$11.1m

Money raised

PhagoMed Biopharma logo

PhagoMed Biopharma

A biotechnology company developing phage therapies to replace ineffective antibiotics.

2

Funding Rounds

$6.4m

Money raised

Axial Therapeutics logo

Axial Therapeutics

Axial Therapeutics is a biopharmaceutical company targeting neurological disorders such as Parkinson's and Autism via gut health.

6

Funding Rounds

$116.0m

Money raised

Second Genome logo

Second Genome

Second Genome is a company that is developing microbiome modulators for infection, immunity and metabolic diseases.

3

Funding Rounds

$67.5m

Money raised

Microbiome Insights logo

Microbiome Insights

Microbiome Insights is a microbiome services and bioinformatics company.

7

Funding Rounds

$1.4m

Money raised

Animab logo

Animab

Animab is a Ghent-based biotechnology company developing products for livestock health.

2

Funding Rounds

$13.8m

Money raised

Gnubiotics Sciences SA logo

Gnubiotics Sciences SA

A Swiss biotech company active in research and development related to breast milk.

6

Funding Rounds

$6.3m

Money raised

Biocrates Life Sciences AG logo

Biocrates Life Sciences AG

Biocrates Life Sciences AG is an Innsbruck-based medical diagnostics company focused on metabolomic research and technology.

8

Funding Rounds

$13.6m

Money raised

Astarte Medical Partners logo

Astarte Medical Partners

Astarte Medical Partners is a startup company headquartered in Yardley, Pennsylvania developing microbial health informatics software that helps optimize nutrition and gut health in preterm infants.

2

Funding Rounds

$9.4m

Money raised

Seed Health logo

Seed Health

Seed Health is a company founded in 2015.

1

Funding Rounds

$40.0m

Money raised

AM Pharma logo

AM Pharma

AM-Pharma is a biopharmaceutical company developing recombinant human Alkaline Phosphatase (AP) therapeutics, which have the potential to treat patients with Acute Kidney Injury, Inflammatory Bowel Disease and Hypophosphatasia.

3

Funding Rounds

$302.8m

Money raised

Dermala logo

Dermala

A biotechnology company offering personalized kits for treating acne based on an individuals microbiome.

4

Funding Rounds

$14.4m

Money raised

CosmosID logo

CosmosID

CosmosID is a microbial genomics platform focused on characterization of microorganisms, pathogens and anti-microbial resistance for infectious disease identification, food safety inspections, pharmaceutical discovery, public health surveillance and microbiome analysis.

3

Funding Rounds

$7.3m

Money raised

GRO Biosciences logo

GRO Biosciences

GRO Biosciences was founded by Dr. George Church at the Harvard Life Lab.

5

Funding Rounds

$35.1m

Money raised

MicroBiome Therapeutics logo

MicroBiome Therapeutics

MicroBiome Therapeutics is a New Orleans-based company founded by Dale Pfost.

3

Funding Rounds

$2.3m

Money raised

OrphoMed logo

OrphoMed

OrphoMed is a clinical-stage biotechnology company with a proprietary dimer therapeutics platform. The company is focused on developing treatments for patients with gastrointestinal disorders.

1

Funding Rounds

$39.0m

Money raised

EnteroBiotix logo

EnteroBiotix

EnteroBiotix is a fecal microbiota transplantation founded in 2017 by James McIlroy.

7

Funding Rounds

$90.2m

Money raised

Persephone Biosciences logo

Persephone Biosciences

Persephone Biosciences is a company focused on microbiome therapeutics and research.

1

Funding Rounds

$15.0m

Money raised

Carbiotix logo

Carbiotix

Carbiotix is a personalized nutrition company that produces consumer gut health products and microbiome therapeutics.

4

Funding Rounds

$1.3m

Money raised

Microbiotica Limited logo

Microbiotica Limited

Microbiotica Limited is a gut Bacteria Phenotype to Biomarker/Therapeutics founded in 2016 by Mike Romanos.

5

Funding Rounds

$166.1m

Money raised

Shoreline Biome logo

Shoreline Biome

Shoreline Biome is a Farmington, CT-based biotechnology company offering kits for microbiome analysis.

3

Funding Rounds

$2.9m

Money raised

Micreos logo

Micreos

Developer of phage technology for targeted control of bacteria.

3

Funding Rounds

$63.0m

Money raised

Bactana logo

Bactana

A company that develops a microbiome discovery platform for animal health.

4

Funding Rounds

$3.6m

Money raised

Ab-Biotics logo

Ab-Biotics

Ab-Biotics is a company founded in 2004 by Miquel Àngel Bonachera.

2

Funding Rounds

$783.1k

Money raised

Ample logo

Ample

Ample is a company producing health focused meal replacements founded in 2015 by Bryan Rosenblatt, MARK DIVINE and Connor Young.

2

Funding Rounds

$4.0m

Money raised

Rebiotix logo

Rebiotix

Rebiotix is a company that is deveoloping microbiota restoration therapy for the treatment of gastrointestinal diseases.

3

Funding Rounds

$36.3m

Money raised

Zbiotics logo

Zbiotics

Zbiotics is a company creating genetically engineered probiotics for consumers founded in 2016 by Zachary Abbott.

1

Funding Rounds

$2.3m

Money raised

MetaboGen logo

MetaboGen

Probiotic product development biopharmaceutical company based in Gothenburg, Sweden.

2

Funding Rounds

$2.0m

Money raised

Whole Biome logo

Whole Biome

Whole Biome is a San Francisco-based microbiome diagnostics and therapeutics company.

1

Funding Rounds

$35.0m

Money raised

Epibiome logo

Epibiome

Precision microbiome engineering company. Epibiome using bacteriophages to combat prevent and treat bacterial infection in humans and agriculture.

1

Funding Rounds

$1.0m

Money raised

Gallinée logo

Gallinée

Gallinée produces probiotic skincare products for sensitive skin.

1

Funding Rounds

Exeliom logo

Exeliom

Exeliom is a gut microbiome modifiers founded by Benjamin Hadida, Harry Sokol, Patrick Gervais and Philippe Langella.

1

Funding Rounds

$8.3m

Money raised

Ascus Biosciences logo

Ascus Biosciences

A San Diego-based company that produces endomicrobial products for animals.

2

Funding Rounds

$51.0m

Money raised

3Bar Biologics logo

3Bar Biologics

3Bar Biologics is a microbe delivery and manufacturing company that partners with microbe discovery and commercialization companies.

2

Funding Rounds

$3.0m

Money raised

Microba Life Sciences Limited logo

Microba Life Sciences Limited

Microba Life Sciences Limited is a company founded in 2018 by Gene Tyson.

2

Funding Rounds

$10.2m

Money raised

BCD Bioscience, Inc. logo

BCD Bioscience, Inc.

BCD Bioscience is a Davis, California-based biotechnology company developing ingredients for food, agriculture, and biopharmaceutical applications.

2

Funding Rounds

$16.8m

Money raised

ClostraBio, Inc logo

ClostraBio, Inc

ClostraBio, Inc is discovering and developing new therapeutics that modulate the protective ability of the microbiome.

2

Funding Rounds

$3.5m

Money raised

PharmaBiome logo

PharmaBiome

PharmaBiome is a microbiome company.

4

Funding Rounds

$2.1m

Money raised

Matrisys Bioscience, Inc. logo

Matrisys Bioscience, Inc.

Matrisys Bioscience, Inc. is a dermatology & Skin Care founded in 2015 by Richard Gallo.

3

Funding Rounds

$64.7m

Money raised

Symbiotic Health logo

Symbiotic Health

Symbiotic Health is a microbiome therapeutics for treating C. diff infections founded in 2013 by Gerard Honig.

2

Funding Rounds

$1.0m

Money raised

S-Biomedic logo

S-Biomedic

S-Biomedic brings novel therapeutic solutions to the skin microbiome. S-Biomedic uses a targeted modulation-based technology to modify the skin microbiome. This technology can be applied in both the dermatology and cosmetic industries.

1

Funding Rounds

$4.4m

Money raised