69 Best Biopharmaceutical Startups to Watch in 2025

The Definitive Seedtable Ranking of Biopharmaceutical Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 793 start-ups with an aggregate funding of $7.5b. The average funding per company in this subset is $108.8m.

Last update to the database: Feb 18, 2025. See changelog.

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Deep Genomics logo

Deep Genomics

A genetic medicine company that build data platforms using synthetic biology, artificial intelligence and genetic medicine for the development of medical therapies.

5

Funding Rounds

$236.7m

Money raised

Insilico Medicine logo

Insilico Medicine

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

6

Funding Rounds

$356.3m

Money raised

Leo Cancer Care logo

Leo Cancer Care

Leo Cancer Care is a company developing upright radiotherapy solutions.

1

Funding Rounds

$25.3m

Money raised

OncoImmune logo

OncoImmune

A clinical-stage biopharmaceutical company engaging in drug discovery and drug development for treating autoimmune disease and cancer.

5

Funding Rounds

$76.5m

Money raised

Senti Biosciences logo

Senti Biosciences

Senti Biosciences is a synthetic biology company.

2

Funding Rounds

$158.0m

Money raised

Visterra logo

Visterra

A company developing antibody-based biological medicines for kidney diseases and other chronic diseases. Visterra was acquired by Otsuka Pharmaceutical in 2018.

4

Funding Rounds

$153.7m

Money raised

Paige logo

Paige

Paige provides AI-based digital diagnostics and a vendor-neutral platform designed to drive diagnostic confidence and a more productive pathology workflow.

10

Funding Rounds

$410.0m

Money raised

BlueRock Therapeutics logo

BlueRock Therapeutics

A biotechnology company developing engineered cell therapies for treating diseases in neurology, cardiology and autoimmunity.

1

Funding Rounds

$225.0m

Money raised

Vedanta Biosciences logo

Vedanta Biosciences

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

13

Funding Rounds

$386.6m

Money raised

RoosterBio logo

RoosterBio

RoosterBio is a biotechnology company located in Frederick, Maryland, founded by Jon Rowley in 2013 providing standardized stem cell products for R&D, clinical, and commercial use in the regenerative medicine industry.

3

Funding Rounds

$21.5m

Money raised

Neos Therapeutics logo

Neos Therapeutics

Neos Therapeutics is a pharmaceutical company developing ADHD medications founded in 2008.

1

Funding Rounds

$24.1m

Money raised

Cala Health logo

Cala Health

Cala Health offers bioelectronic medicines, medical devices, and neurotherapeutics for managing chronic health conditions.

3

Funding Rounds

$145.0m

Money raised

Kuur Therapeutics logo

Kuur Therapeutics

Kuur Therapeutics focuses on the development of CAR-NKT cell therapies platform for applications in cancer treatment.

6

Funding Rounds

$190.5m

Money raised

Promethera Biosciences logo

Promethera Biosciences

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

5

Funding Rounds

$103.1m

Money raised

Massive Bio logo

Massive Bio

Massive Bio is a New York-based company founded by Selin Kurnaz, Dr. Arturo Loaiza-Bonilla and Cagatay M. Culcuoglu, offering precision oncology services to cancer patients, providers, and pharmaceutical companies.

6

Funding Rounds

$15.8m

Money raised

Eligo Bioscience logo

Eligo Bioscience

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

9

Funding Rounds

$82.6m

Money raised

Stemline Therapeutics logo

Stemline Therapeutics

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

2

Funding Rounds

$13.8m

Money raised

Miragen Therapeutics logo

Miragen Therapeutics

miRagen is a clinical stage biopharmaceutical company developing innovative microRNA-targeting therapies to improve human health.

3

Funding Rounds

$32.0m

Money raised

Alkahest logo

Alkahest

A company developing anti-aging treatments using components derived from human blood.

3

Funding Rounds

$41.0m

Money raised

Ligandal logo

Ligandal

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

6

Funding Rounds

$4.6m

Money raised

ApexQubit logo

ApexQubit

ApexQubit is a biotechnology company that is harnessing a proprietary technology for discovery of new medicines to treat patients with undruggable diseases.

3

Funding Rounds

$54.1k

Money raised

Prokarium logo

Prokarium

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

6

Funding Rounds

$86.6m

Money raised

Vaxess Technologies logo

Vaxess Technologies

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

14

Funding Rounds

$87.2m

Money raised

Evox Therapeutics logo

Evox Therapeutics

An exosome therapeutics company founded in 2016 and based in Oxford, UK, that uses exosomes to deliver small and large molecule therapeutics. The company has a proprietary technology to modify exosomes to target specific organs such as the brain and central nervous system.

3

Funding Rounds

$143.4m

Money raised

Cellink AB (publ) logo

Cellink AB (publ)

Cellink AB is a biotechnology research company based in Gothenburg.

2

Funding Rounds

$4.5m

Money raised

LifeMine Therapeutics logo

LifeMine Therapeutics

A therapeutics company founded in 2016 working in drug discovery and development using fungi. LifeMine uses genomics approaches to search for biosynthetic genes in eukaryotic microbes for the discovery of naturally inspired drugs to treat previously untreatable and significant chronic diseases.

3

Funding Rounds

$280.0m

Money raised

Lung Therapeutics logo

Lung Therapeutics

Lung Therapeutics is a therapeutics for lung injury and disease company founded in 2013 by Andrew Mazar, Steven Idell and Sreerama Shetty.

2

Funding Rounds

$50.3m

Money raised

Cellerant Therapeutics logo

Cellerant Therapeutics

A biotechnology company that develops treatments for cancer and hematologic conditions

2

Funding Rounds

$18.1m

Money raised

Antheia logo

Antheia

Antheia is an American biotechnology company founded in 2013, and is located in Menlo Park, California. Antheia uses synthetic biology, informatics, and fermentation technologies to produce plant based medicines; most notably opioids using yeast.

1

Funding Rounds

$73.0m

Money raised

Codagenix logo

Codagenix

A biotechnology company developing live attenuated vaccines. It was founded in 2012 and is located in New York.

5

Funding Rounds

$26.8m

Money raised

Aetion logo

Aetion

Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.

6

Funding Rounds

$230.6m

Money raised

Dharmacon, Inc. logo

Dharmacon, Inc.

Dharmacon, Inc. is a Lafayette, Colorado-based company founded in 1995.

Avro Life Science logo

Avro Life Science

Avro is a life sciences company, located in Canada and founded in 2016 by Shakir Lakhani and Keean Waterloo, Ontario, that makes skin patches capable of delivering generic drugs.

2

Funding Rounds

$120.0k

Money raised

3T Biosciences logo

3T Biosciences

3T Biosciences is a biotechnology company developing immunotherapies.

3

Funding Rounds

$52.0m

Money raised

SmartPharm Therapeutics logo

SmartPharm Therapeutics

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

1

Funding Rounds

$10.5m

Money raised

Intarcia Therapeutics logo

Intarcia Therapeutics

Formerly BioMedicines, Intarcia Therapeutics is an American biopharmaceutical company developing therapies for diseases with long-term treatment requirements.

4

Funding Rounds

$479.5m

Money raised

Oxford Drug Design Limited logo

Oxford Drug Design Limited

Oxford Drug Design Limited is a company that focuses on developing and delivering services and technologies for computer-aided drug discovery

5

Funding Rounds

$10.0m

Money raised

Tmunity Therapeutics logo

Tmunity Therapeutics

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

5

Funding Rounds

$425.0m

Money raised

Palvella Therapeutics, Inc. logo

Palvella Therapeutics, Inc.

Palvella Therapeutics is committed to developing safe and effective therapies that specifically target the root cause of genetic skin diseases.

2

Funding Rounds

$55.0m

Money raised

Oxford Genetics logo

Oxford Genetics

Oxford Genetics, also known as Oxgene, is a synthetic biology company specializing in DNA design, protein expression optimization and cell line development technologies and services.

7

Funding Rounds

$31.4m

Money raised

Nucleai logo

Nucleai

An artificial intelligence company with a focus on developing solutions for the healthcare industry. It was founded in 2017 and is located in Tel Aviv, Israel.

2

Funding Rounds

$11.5m

Money raised

Juventus Therapeutics logo

Juventus Therapeutics

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

4

Funding Rounds

$46.7m

Money raised

CHAIN Biotechnology logo

CHAIN Biotechnology

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

2

Funding Rounds

$645.0k

Money raised

Foundation Medicine logo

Foundation Medicine

Foundation Medicine is a Cambridge, Massachusetts-based pharmaceutical company developing diagnostic and treatment solutions for cancer care founded in 2010 by Alexis Borisy.

4

Funding Rounds

$96.5m

Money raised

Hyperion Therapeutics logo

Hyperion Therapeutics

A biopharmaceutical company focused on developing treatments for urea cycle disorders and other rare diseases

3

Funding Rounds

$117.5m

Money raised

Siolta Therapeutics logo

Siolta Therapeutics

Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.

2

Funding Rounds

$30.0m

Money raised

OncoSenX logo

OncoSenX

OncoSenX is a spinout company of Oisin Biotechnologies, formed to develop programmable suicide gene therapy to kill cancerous cells.

5

Funding Rounds

$19.7m

Money raised

Horizon Discovery logo

Horizon Discovery

Horizon Discovery is a company that offers gene editing, CRO, and diagnostics services

5

Funding Rounds

$30.9m

Money raised

64x Bio logo

64x Bio

64x Bio is a biotechnology company developing a platform for improving speed and scalability of mammalian cell line discovery for pharmaceutical and biotechnology companies.

3

Funding Rounds

$59.5m

Money raised

Aqemia logo

Aqemia

AI-powered drug discovery platform.

3

Funding Rounds

$69.5m

Money raised

Genecentric Diagnostics, Inc. logo

Genecentric Diagnostics, Inc.

Genecentric Diagnostics, Inc. is an oncology diagnostic and treatment center.

4

Funding Rounds

$13.9m

Money raised

Stelvio Therapeutics logo

Stelvio Therapeutics

Stelvio Therapeutics is a biotechnology company developing therapeutics for cancer.

1

Funding Rounds

Gatehouse Bio logo

Gatehouse Bio

A bio-data company that uses AI to analyze RNA sequencing data

2

Funding Rounds

$5.4m

Money raised

Novo Biosciences logo

Novo Biosciences

A pharmaceutical company that uses a zebrafish drug-screening platform to find drug candidate molecules that have the capacity to promote regeneration of tissues. Their drug candidate MSI-1436 is being developed and tested for the treatment of heart disease, Duchenne Muscular Dystrophy and diabetic nephropathy.

1

Funding Rounds

$4.0m

Money raised

Verge Genomics logo

Verge Genomics

Verge Genomics is a company focused on the discovery and development of drugs for the treatment of neurodegenerative diseases with the use of machine learning and computational genomics.

5

Funding Rounds

$134.1m

Money raised

Snipr Biome logo

Snipr Biome

Snipr Biome is a synthetic biology company using CRISPR to make products for the microbiome.

2

Funding Rounds

$100.0m

Money raised

Azitra logo

Azitra

A company based in Farmington, Connecticut, that develops skin disease treatments using microbiome science and technology.

9

Funding Rounds

$56.6m

Money raised

Haya Therapeutics logo

Haya Therapeutics

RNA-guided regulatory genome targeting therapeutics developer for chronic diseases.

2

Funding Rounds

$1.0b

Money raised

DCPrime logo

DCPrime

DCPrime is a biotechnology company developing cancer immunotherapies.

5

Funding Rounds

$26.0m

Money raised

BrainCo logo

BrainCo

A company utilizing BMI and Neurofeedback to optimize brain potential.

3

Funding Rounds

$6.0m

Money raised

Turbine.ai logo

Turbine.ai

Turbine.ai is a Budapest-based drug discovery company founded in 2015 by Daniel Veres, Kristóf Zsolt Szalay and Szabolcs Nagy.

3

Funding Rounds

$31.1m

Money raised

Wyss Institute at Harvard logo

Wyss Institute at Harvard

An institute for research at Harvard University for developing bioinspired materials and medical devices.

1

Funding Rounds

$37.0m

Money raised

JW (Cayman) Therapeutics Co. Ltd logo

JW (Cayman) Therapeutics Co. Ltd

JW (Cayman) Therapeutics Co. Ltd is a Shanghai-based developer of cell-based therapy technologies for cancer treatment.

2

Funding Rounds

$195.5m

Money raised

IGM Biosciences logo

IGM Biosciences

IGM Biosciences is an antibody Treatments.

2

Funding Rounds

$204.0m

Money raised

Aprinoia Therapeutics logo

Aprinoia Therapeutics

Aprinoia Therapeutics is a developer of diagnostics, therapeutics and drug discovery platform for neurological diseases.

1

Funding Rounds

$11.1m

Money raised

resTORbio logo

resTORbio

A biopharmaceutical company developing therapeutics for treating age-related diseases.

3

Funding Rounds

$105.0m

Money raised

Eureka Therapeutics, Inc logo

Eureka Therapeutics, Inc

Eureka Therapeutics is a biotechnology company developing immunotherapies for the treatment of cancer.

2

Funding Rounds

$105.0m

Money raised

Chiasma Pharma logo

Chiasma Pharma

Chiasma Pharma is a Waltham, Massachusetts-based biopharmaceutical company developing oral drugs for the treatment of orphan diseases.

3

Funding Rounds

$90.2m

Money raised

Neurelis Inc logo

Neurelis Inc

Neurelis Inc. is a private specialty pharmaceutical company based in San Diego, California, US, providing treatment options for epilepsy and central nervous system disorders.

1

Funding Rounds

$114.0m

Money raised