69 Best Drug Development Startups to Watch in 2025

The Definitive Seedtable Ranking of Drug Development Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 86 start-ups with an aggregate funding of $5.2b. The average funding per company in this subset is $75.5m.

Last update to the database: Feb 18, 2025. See changelog.

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PathAI (company) logo

PathAI (company)

PathAI is a Boston-based artificial intelligence company developing therapeutics and healthcare products.

5

Funding Rounds

$390.0m

Money raised

Insilico Medicine logo

Insilico Medicine

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

6

Funding Rounds

$356.3m

Money raised

Tempus Labs (company) logo

Tempus Labs (company)

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

10

Funding Rounds

$930.0m

Money raised

Notable Labs logo

Notable Labs

Notable Labs is a company providing personalized drug combination testing service for cancer patients.

8

Funding Rounds

$71.3m

Money raised

Inato logo

Inato

Inato matches the right sites to the right clinical research study, globally.

4

Funding Rounds

$49.6m

Money raised

Trials.ai logo

Trials.ai

Trials.ai is an artificial intelligence company founded by Kim Walpole and Tom Walpole.

4

Funding Rounds

Aicure logo

Aicure

AiCure is an advanced data analytics company that uses artificial intelligence to understand how patients respond to treatments.

4

Funding Rounds

$76.3m

Money raised

Massive Bio logo

Massive Bio

Massive Bio is a New York-based company founded by Selin Kurnaz, Dr. Arturo Loaiza-Bonilla and Cagatay M. Culcuoglu, offering precision oncology services to cancer patients, providers, and pharmaceutical companies.

6

Funding Rounds

$15.8m

Money raised

Eligo Bioscience logo

Eligo Bioscience

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

9

Funding Rounds

$82.6m

Money raised

Alkahest logo

Alkahest

A company developing anti-aging treatments using components derived from human blood.

3

Funding Rounds

$41.0m

Money raised

OrphAI Therapeutics logo

OrphAI Therapeutics

OrphAI Therapeutics is a biotechnology research company based in Guilford, Connecticut that develops precision therapeutics technology designed to treat cancer and rare diseases.

2

Funding Rounds

$98.0m

Money raised

ApexQubit logo

ApexQubit

ApexQubit is a biotechnology company that is harnessing a proprietary technology for discovery of new medicines to treat patients with undruggable diseases.

3

Funding Rounds

$54.1k

Money raised

Chronicled logo

Chronicled

Chronicled is a blockchain company founded by Ryan Orr, Samantha Radocchia, Maurizio Greco and David Aho.

10

Funding Rounds

$36.3m

Money raised

Alzheon logo

Alzheon

Develops medicines for patients suffering from Alzheimer's disease and other neurological disorders.

8

Funding Rounds

$92.7m

Money raised

Deep Lens logo

Deep Lens

Deep Lens is an Artificial Intelligence company matching patients with clinical trials.

3

Funding Rounds

$31.2m

Money raised

Athelas logo

Athelas

Athelas is a company developing blood testing device that utilizes deep learning and computer vision.

5

Funding Rounds

$155.6m

Money raised

Deep 6 AI logo

Deep 6 AI

Deep 6 AI is an artificial Intelligence company founded by Wout Brusselaers.

3

Funding Rounds

$34.0m

Money raised

Ichor Therapeutics logo

Ichor Therapeutics

Ichor Therapeutics is a pre-clinical contract research on aging mechanisms company founded in 2013 by Kelsey Moody.

5

Funding Rounds

$2.5m

Money raised

Mendel.ai logo

Mendel.ai

Mendel.ai is a life science company offering an artificial intelligence platform to aid clinical experts improve their clinical cancer research.

7

Funding Rounds

$65.4m

Money raised

Oisin Biotechnologies logo

Oisin Biotechnologies

Oisin develops anti-aging treatments that target and remove senescent cells, a type of damaged cell that is unable to divide, accumulates during aging and contribute to age-related diseases.

4

Funding Rounds

$7.1m

Money raised

Biofourmis logo

Biofourmis

Biofourmis is a global health IT start-up in Massachusetts that focuses on personalized care and therapies using digital therapeutics.

7

Funding Rounds

$443.5m

Money raised

Reverie Labs logo

Reverie Labs

Reverie Labs is a drug dicovery company that uses machine learning founded by Jonah Kallenbach.

2

Funding Rounds

$25.0m

Money raised

resTORbio logo

resTORbio

A biopharmaceutical company developing therapeutics for treating age-related diseases.

3

Funding Rounds

$105.0m

Money raised

Intelligencia logo

Intelligencia

An artificial intelligence company with a platform to be used the drug discovery process. It was founded in 2017 and is located in New York City.

1

Funding Rounds

$12.0m

Money raised

PostEra logo

PostEra

PostEra is a biotechnology company that uses machine learning for medicinal chemistry services.

3

Funding Rounds

$26.5m

Money raised

NetraMark logo

NetraMark

NetraMark is a Toronto-based machine learning software company founded by Joseph Geraci in 2015.

1

Funding Rounds

Anviro Therapeutics logo

Anviro Therapeutics

Anviro Therapeutics is a biotechnology company developing broad spectrum antiviral therapies.

1

Funding Rounds

$650.0k

Money raised

Healx logo

Healx

Healx is a biotechnology therapeutics company for rare diseases founded in 2014 by Tim Guilliams.

4

Funding Rounds

$124.1m

Money raised

Medable logo

Medable

Medable's offers a healthcare application that provides patient-generated data for researchers, health startups, pharmaceuticals and universities.

7

Funding Rounds

$506.6m

Money raised

Argonaut Therapeutics logo

Argonaut Therapeutics

Precision therapeutics company developing epigenetic therapies that target arginine methylation in cancer.

2

Funding Rounds

$2.6m

Money raised

SEngine Precision Medicine logo

SEngine Precision Medicine

SEngine Precision Medicine is a precision medicine company founded by Brady Bernard, Carla Grandori, Christopher Kemp, and VK Gadi.

2

Funding Rounds

$8.1m

Money raised

Arrakis Therapeutics logo

Arrakis Therapeutics

Arrakis is developing RNA-targeted small molecule (rSM) therapies to millions of patients.

4

Funding Rounds

$226.0m

Money raised

X-37 logo

X-37

X-37 is a South San Francisco, California-based drug discovery company.

1

Funding Rounds

$14.5m

Money raised

Mekonos logo

Mekonos

Mekonos is a company that creates cell-engineering platforms

3

Funding Rounds

$31.0m

Money raised

Atomic AI logo

Atomic AI

Atomic AI is a biotechnology company specializing in the development of a platform for RNA drug discovery.

2

Funding Rounds

$42.0m

Money raised

ScienceIO logo

ScienceIO

ScienceIO is a Boston-based company developing an artificial intelligence-powered evidence exploration and synthesis platform.

2

Funding Rounds

$8.0m

Money raised

Orexigen Therapeutics logo

Orexigen Therapeutics

Orexigen Therapeutics is a biopharmaceutical company developing treatments for obesity founded in 2002 by Eckard Weber.

3

Funding Rounds

$76.0m

Money raised

PatchAI logo

PatchAI

A virtual assistant in Italy that focuses on improving people's quality of life and supporting the process of developing innovative and personalized drugs.

1

Funding Rounds

$2.2m

Money raised

CysBio logo

CysBio

A company using metabolic engineering and synthetic biology to produce biochemicals from renewable feedstocks.

3

Funding Rounds

$18.4m

Money raised

Coral Genomics logo

Coral Genomics

Coral is a biotechnology company, founded in 2018, that creates large datasets which represent the diversity of human biology to improve development and deployment of drugs and make clinical trials more efficient through predicting patient responses to drugs.

3

Funding Rounds

$5.7m

Money raised

Targazyme logo

Targazyme

Targazyme is a biotechnology company focused on improving survival and quality of life for cancer patients using stem cell transplantation, immunotherapy, regenerative medicine, and gene therapy.

1

Funding Rounds

$2.5m

Money raised

Gotham Therapeutics logo

Gotham Therapeutics

A biotechnology company discovering drugs that target the epitranscriptomics machinery that modifies RNA.

1

Funding Rounds

$54.0m

Money raised

Theranostics Health logo

Theranostics Health

A proteomics-based diagnostics company providing research services for the development of personalized medicine

6

Funding Rounds

$5.1m

Money raised

Trialspark logo

Trialspark

Trialspark is a company founded in 2013 by Benjamine Liu, kit dobyns and linhao zhang.

3

Funding Rounds

$156.0m

Money raised

Aiforia logo

Aiforia

Aiforia is a Helsinki-based artificial intelligence company developing image analysis technology for diagnostics.

6

Funding Rounds

$76.9m

Money raised

Datavant logo

Datavant

Datavant is a San Francisco-based company founded in 2017.

2

Funding Rounds

$80.0m

Money raised

Entos Pharmaceuticals Inc. logo

Entos Pharmaceuticals Inc.

Entos Pharmaceuticals develops nucleic acid-based therapies using its proprietary Fusogenix drug delivery system.

1

Funding Rounds

ImmunoBiochem logo

ImmunoBiochem

Immunobiochem is a biotechnology company that is committed to addressing unmet medical need in oncology via research and development of novel, targeted biological therapeutics.

2

Funding Rounds

Unlearn.AI logo

Unlearn.AI

Unlearn is a San Francisco, California-company developing artificial intelligence tools and software for medical research.

5

Funding Rounds

$69.9m

Money raised

NemaMetrix logo

NemaMetrix

NemaMetrix is a drug discovery company founded in 2011 by Matt Beaudet.

9

Funding Rounds

$15.9m

Money raised

Phenomic AI logo

Phenomic AI

Phenomic AI is a Toronto-based company.

4

Funding Rounds

$8.0m

Money raised

celldom logo

celldom

celldom is a single cell omics company founded in 2016 by Zach Forbes, Benjamin Yellen and Kris Wood.

4

Funding Rounds

$2.0m

Money raised

Glympse Bio logo

Glympse Bio

Glympse Bio is developing a powerful new paradigm in diagnostics to enable noninvasive and predictive monitoring of multiple human diseases.

5

Funding Rounds

$94.3m

Money raised

Ionpath logo

Ionpath

Ionpath is a Menlo Park, California-based medical diagnostic tool company.

3

Funding Rounds

$18.0m

Money raised

Nodality logo

Nodality

A company developing treatments for cancer and autoimmune diseases

3

Funding Rounds

$13.5m

Money raised

Winterlight Labs logo

Winterlight Labs

A company making voice recognition products capable of detecting cognitive decline and cognitive impairment based on samples of speech.

1

Funding Rounds

$4.2m

Money raised

Expansion Therapeutics logo

Expansion Therapeutics

Expansion Therapeutics is a RNA Targeted Small Molecules founded in 2016.

2

Funding Rounds

$135.3m

Money raised

AstronauTx logo

AstronauTx

AstronauTx is a London-based biotechnology research company developing treatments for neurogenerative diseases.

6

Funding Rounds

$195.8m

Money raised

Qynapse logo

Qynapse

Qynapse provides an FDA-Cleared neuroimaging software platform.

1

Funding Rounds

$2.8m

Money raised

ValiRx PLC. logo

ValiRx PLC.

ValiRx PLC. is a Cambridge, Massachusetts-based healthcare accelerator working to develop new medicines and technologies founded in 2000.

1

Funding Rounds

$1.2m

Money raised

TVAX Biomedical logo

TVAX Biomedical

A biotechnology company developing targeted cell-based immunotherapies for the treatment of cancer

1

Funding Rounds

$2.0m

Money raised

Microdermics logo

Microdermics

Microdermics is a skincare company founded in 2014 by Grant Campany, Boris Stoeber, Sahan Ranamukhaarachchi and Iman Mansoor.

2

Funding Rounds

$1.5m

Money raised

Remedy Plan logo

Remedy Plan

A company developing drugs that halt tumor growth and disrupt metastasis

1

Funding Rounds

$7.2m

Money raised

KPI Therapeutics logo

KPI Therapeutics

KPI Therapeutics is a company that focuses on developing potentially game changing autoimmune therapies.

3

Funding Rounds

$27.0k

Money raised

BioMotiv logo

BioMotiv

BioMotiv is a company focused on advancng therapeutics development founded in 2012.

1

Funding Rounds

$21.0m

Money raised

Oncomatryx logo

Oncomatryx

Developer of ADCs to treat metastatic solid tumors.

2

Funding Rounds

$21.3m

Money raised

GERO (company) logo

GERO (company)

GERO is a small Molecules founded in 2015 by Maxim Kholin.

2

Funding Rounds

$4.4m

Money raised

Deep Intelligent Pharma logo

Deep Intelligent Pharma

Deep Intelligent Pharma is a drug researching company with focus in artificial intelligence.

2

Funding Rounds

$6.6m

Money raised

Dalriada Therapeutics logo

Dalriada Therapeutics

Dalriada Therapeutics is a Mississauga-based research and development company offering a diagnostics and drug discovery platform.

1

Funding Rounds