58 Best Startups in Rockville Maryland to Watch in 2025

The Definitive Seedtable Ranking of Startups in Rockville Maryland

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 58 start-ups with an aggregate funding of $2.0b. The average funding per company in this subset is $34.8m.

Last update to the database: Feb 18, 2025. See changelog.

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1

Funding Rounds

$60.0m

Money raised

6

Funding Rounds

$356.3m

Money raised

Insilico Medicine is a drug discovery, artificial intelligence company that looks to treat cancer and age related diseases

5

Funding Rounds

$76.5m

Money raised

A clinical-stage biopharmaceutical company engaging in drug discovery and drug development for treating autoimmune disease and cancer.

2

Funding Rounds

$27.4m

Money raised

A nonprofit genomic research institute dedicated to advances in human health and the environment.

2

Funding Rounds

$4.7m

Money raised

Biotechnology company providing protein analysis tools and commercializing diagnostic tests

2

Funding Rounds

$60.6m

Money raised

A biotechnology company developing nucleic acid immunotherapy platform and protein based vaccines

4

Funding Rounds

$6.0m

Money raised

AGT is developing and commercializing gene and cell therapy and targeting major diseases, including HIV/AIDS, Phenylketonuria (PKU) and Hepatocellular carcinoma.

6

Funding Rounds

$5.1m

Money raised

A proteomics-based diagnostics company providing research services for the development of personalized medicine

3

Funding Rounds

$7.3m

Money raised

CosmosID is a microbial genomics platform focused on characterization of microorganisms, pathogens and anti-microbial resistance for infectious disease identification, food safety inspections, pharmaceutical discovery, public health surveillance and microbiome analysis.

11

Funding Rounds

$91.9m

Money raised

A company that offers DNA analysis and genome mapping system

5

Funding Rounds

$64.3m

Money raised

Curetis is a Holzheim am Forst-based molecular diagnostic firm developing tools for diagnostics of infectious disease.

3

Funding Rounds

$36.3m

Money raised

Rebiotix is a company that is deveoloping microbiota restoration therapy for the treatment of gastrointestinal diseases.

3

Funding Rounds

$53.0m

Money raised

CloudBolt provide solutions for your toughest cloud challenges.

7

Funding Rounds

$58.5m

Money raised

Motionsoft does SaaS payment processing & full-service billing solutions for fitness clubs, corporate fitness facilities + hospital wellness centers.

4

Funding Rounds

$33.5m

Money raised

Developer of a mobile real estate search platform designed to explore homes and search listings. The company's platform provides detailed listings, gives instant access to school attendance zones, property lines, property history, and also provides customized news feed and notifications to give information in real-time, enabling users to find and discuss homes all in one place.

3

Funding Rounds

$10.5m

Money raised

Sepio is a leader in the Rogue Device Mitigation (RDM) market, and the developer of Sepio Prime - a SaaS solution for protecting organizations from hardware based attacks and threats.

1

Funding Rounds

$75.0m

Money raised

Encodia Inc. is a protein Analysis Technologies founded in 2015.

2

Funding Rounds

$59.7m

Money raised

Kolon TissueGene is a biotechnology company developing cell and gene therapies for treating osteoarthritis.

2

Funding Rounds

$10.5m

Money raised

AAV, lentivirus and adenovirus based products and custom services

1

Funding Rounds

$1.3m

Money raised

Weinberg Medical Physics LLC is a company founded in 2008.

2

Funding Rounds

$12.5m

Money raised

A biotechnology company dectecting multiple biomarkers and biomarker signatures using proteomics

6

Funding Rounds

$9.5m

Money raised

Machfu is a company founded in 2015 by Prakash Chakravarthi.

1

Funding Rounds

$5.5m

Money raised

Hillcrest Labs is a Rockville, Maryland-based company founded in 2001 by Dan Simpkins.

1

Funding Rounds

$500.0m

Money raised

X-energy is a developer of advanced modular nuclear reactors and fuel technology for clean energy generation.

2

Funding Rounds

$15.0m

Money raised

Cellphire Therapeutics, Inc. is a Rockville, Maryland-based biotechnology company developing therapeutics and technologies for trauma and wound care, imaging, targeted drug delivery, and regenerative medicine.

5

Funding Rounds

$21.0m

Money raised

A company developing pathogen detection and diagnostic systems comprised of biosensors

1

Funding Rounds

$20.0m

Money raised

A company developing immune-based biologics for the treatment of cancer, autoimmunity, transplantation and infectious diseases

12

Funding Rounds

$21.1m

Money raised

CytImmune Sciences is a clinical-stage biopharmaceutical company developing nano-medicines, anti-cancer agents, and semi-synthetic in vitro immune systems that help produce antibodies.

1

Funding Rounds

$100.0k

Money raised

Ariadne Diagnostics is a company founded in 2011 by Ilya Mazo.

1

Funding Rounds

$2.3m

Money raised

Otomagnetics, Inc. is a biotechnology company focused on the development of noninvasive drug delivery equipment and technology.

1

Funding Rounds

$4.2m

Money raised

3CLogic is a Rockville, Maryland-based company founded in 2005 by Denis Seynhaeve, Raj Sharma and Sirish Bajpai.

2

Funding Rounds

$38.7m

Money raised

A pharmaceutical company developing antibiotics to treat drug resistant bacterial, fungal and parasitic infections.

2

Funding Rounds

$250.0k

Money raised

V-Sense Medical Devices is a company developing remote monitoring system for patients' vital signs using NASA radar technology.

1

Funding Rounds

$1.7m

Money raised

A phamaceutical company in Bangladesh developing therapeutic technology for the treatment of gastrointestinal diseases

1

Funding Rounds

$25.0m

Money raised

A medical device company developing transcatheter for mitral valve replacement and repair

5

Funding Rounds

$9.7m

Money raised

AutoSled, Inc. is a company founded in 2019.

1

Funding Rounds

$150.0k

Money raised

A company developing and offering tools for genetic engineering somatic and stem cells

1

Funding Rounds

$3.3m

Money raised

A biotechnology company developing diagnostic products to detect neurodegenerative diseases

1

Funding Rounds

Integrated BioTherapeutics is a vaccines, Biologics, Monoclonals founded in 2009 by M. Javad Aman.

2

Funding Rounds

$1.9m

Money raised

PW Communications is a Rockville, Maryland-based company founded in 1996 by Phyllis Bresler.

2

Funding Rounds

$11.0m

Money raised

Compost Crew provides food scrap collection services for homes and businesses in DC, MD and VA.

Industries:

1

Funding Rounds

$9.0m

Money raised

Triumfant is a Rockville, Maryland-based company founded by Dave Hooks.

1

Funding Rounds

Highstreet IT Solutions is a Rockville, Maryland-based company founded in 1996.

1

Funding Rounds

$400.0k

Money raised

ClearImpact is a Rockville, Maryland-based company founded in 2006.

Industries:

1

Funding Rounds

$3.0m

Money raised

AnalytiCon Discovery is a Rockville, Maryland-based company in the pharmaceuticals industry founded in 2004.

1

Funding Rounds

$2.0m

Money raised

Optimoz, Inc. is a cloud computing company founded in 2013.

1

Funding Rounds

$50.0m

Money raised

OncoC4, Inc. is an antibodies, Immunotherapies founded in 2020.

2

Funding Rounds

$3.8m

Money raised

2

Funding Rounds

$67.0m

Money raised

DrFirst is a Rockville, Maryland-based company.

2

Funding Rounds

$1.1m

Money raised

Xcellerate Biotech, Inc. is a Rockville, Maryland-based company founded in 2019.

1

Funding Rounds

$1.0m

Money raised

KinaRx, Inc. is a Rockville, Maryland-based company founded in 2017.

1

Funding Rounds

$10.0k

Money raised

ExoLytics, Inc. is a Rockville, Maryland-based company founded in 2020.

2

Funding Rounds

$25.6m

Money raised

Inky is a Rockville, Maryland-based company.

2

Funding Rounds

$231.0k

Money raised

MONTGOMERY SURGERY CENTER LP is a Rockville, Maryland-based company.

1

Funding Rounds

$429.6k

Money raised

Ocean City Storage, LLC is a Rockville, Maryland-based company founded in 2019.

1

Funding Rounds

$56.0m

Money raised

Oncolmmune is a Rockville, Maryland-based company.

1

Funding Rounds

$200.0k

Money raised

Penumbra Space, Inc. is a Rockville, Maryland-based company founded in 2022.

1

Funding Rounds

NeuroCytonix Inc. is a Rockville, Maryland-based company.

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