69 Best Vaccine Startups to Watch in 2025

The Definitive Seedtable Ranking of Vaccine Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 84 start-ups with an aggregate funding of $3.2b. The average funding per company in this subset is $46.7m.

Last update to the database: Feb 18, 2025. See changelog.

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6

Funding Rounds

$4.6m

Money raised

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

6

Funding Rounds

$86.6m

Money raised

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

Location:

Key people:

14

Funding Rounds

$87.2m

Money raised

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

Location:

Key people:

12

Funding Rounds

$2.8m

Money raised

HelixNano is a Cambridge, Massachusetts-based biotechnology and artificial intelligence company founded in 2013 by Hannu Rajaniemi and Nikolai Eroshenko.

2

Funding Rounds

$11.3m

Money raised

Emergex aims to tackle the global threat of infectious disease by providing affordable and practical on-demand vaccine solutions.

Key people:

5

Funding Rounds

$26.8m

Money raised

A biotechnology company developing live attenuated vaccines. It was founded in 2012 and is located in New York.

1

Funding Rounds

$10.5m

Money raised

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

1

Funding Rounds

$150.0k

Money raised

CaroGen is an immunotherapy company that develops vaccine candidates that target hepatitis B and C, as well as other viral agents.

Industries:

Key people:

6

Funding Rounds

$227.7m

Money raised

Translate Bio is a clinical-stage mRNA therapeutics company developing medicines to treat diseases caused by protein or gene dysfunction and vaccines against infectious disease pathogens.

2

Funding Rounds

$37.5m

Money raised

A biomedical company in United Kingdom that develops vaccines and vaccine development technology

Key people:

3

Funding Rounds

$68.0m

Money raised

A biotechnology company developing immune-modulation therapies for infectious diseases and cancer leveraging its technology platform and understanding of immune system mechanisms. It was founded in 2009 and is located in Vienna, Austria.

2

Funding Rounds

$10.5m

Money raised

Synthetic biology company developing vaccines and therapeutics using cell-free biology technology

5

Funding Rounds

$72.3m

Money raised

A pharmaceutical company focused on advancement of unmet vaccines against viruses that cause serious human diseases such as respiratory syncytial virus (RSV). Meissa Vaccines applies their platform technology for viral genetic engineering to multiple pathogens.

Key people:

9

Funding Rounds

$4.3m

Money raised

A computational immunology and vaccine development company based in Providence, Rhode Island. It was founded in 1998.

Key people:

5

Funding Rounds

$26.0m

Money raised

DCPrime is a biotechnology company developing cancer immunotherapies.

2

Funding Rounds

$60.6m

Money raised

A biotechnology company developing nucleic acid immunotherapy platform and protein based vaccines

3

Funding Rounds

$50.6m

Money raised

Cambridge, MA-based company developing targeted mRNA therapeutics for cancer and other diseases.

Key people:

2

Funding Rounds

$8.7m

Money raised

A non-profit organization with a focus on scientific and engineering research. It was founded in 1941 and is located in Birmingham, Alabama.

1

Funding Rounds

Biotherapeutics company focused on medicines for chronic inflammation, metabolic disease and autoimmune disease

6

Funding Rounds

$37.4m

Money raised

Developer of vaccines to provide broad-spectrum protection against highly mutating respiratory viruses.

Location:

Key people:

1

Funding Rounds

$14.2m

Money raised

Stemirna Therapeutics is an mRNA therapeutics and nanoparticle formulation company in China focused on treatments for cancer, infectious diseases and rare diseases.

1

Funding Rounds

$22.8m

Money raised

Vaxxas is commercializing a novel vaccination technology that dramatically enhances the performance of existing and next-generation vaccines.

2

Funding Rounds

$950.0k

Money raised

An operator of a biotechnology company in Massachusetts that focuses on improving the manufacture of immuno-therapeutics and dendritic cell-based vaccines.

3

Funding Rounds

$61.4m

Money raised

ISA Pharmaceuticals is a synthetic therapeutic vaccines founded in 2004 by Cornelius Melief.

6

Funding Rounds

$714.0m

Money raised

Secfi is the pre-wealth advisor for startup employees. Figuring out what to do with your equity-based compensation is complicated and expensive and is therefore ignored and neglected. Secfi makes handling startup equity compensation simple and affordable. We build technology that helps employees make the right decisions for their equity compensation. By addressing their biggest concerns they can spend time on things they love doing most. We are hiring! Find out more at https://www.secfi.com/careers/

Location:

Key people:

3

Funding Rounds

$348.5m

Money raised

Vaccine Discovery Technology Affinivax is a biopharmaceutical company developing vaccines that target infectious diseases.

7

Funding Rounds

$24.5m

Money raised

Immunophotonics is a company developing immunotherapy-based treatments for cancer founded in 2012 by Lu Alleruzzo.

Key people:

3

Funding Rounds

$141.0m

Money raised

Bharat Biotech is an Indian vaccine manufacturer and pharmaceutical company.

Location:

Key people:

2

Funding Rounds

$5.0m

Money raised

ANA Therapeutics is a Foster City, California-based developer of a novel corona vaccine.

Key people:

3

Funding Rounds

$2.8m

Money raised

EpiVax Oncology is a Providence, Rhode Island-based company founded by Gad Berdugo, Anne de Groot and Bill Martin.

Key people:

2

Funding Rounds

$49.0m

Money raised

LabConnect provides comprehensive central lab services for clinical development programs including routine and complex laboratory testing for biopharmaceutical and CRO clients.

1

Funding Rounds

$7.5m

Money raised

Flexible platform vaccine technology designed to elicit both humoral and cellular immune responses in hosts

3

Funding Rounds

$65.1m

Money raised

MinervaX is a Copenhagen-based company founded in 2010 by Per Fischer.

Location:

Key people:

1

Funding Rounds

$56.0m

Money raised

Biotechnology company focused on developing vaccines for herpes.

3

Funding Rounds

$26.8m

Money raised

Mazen Animal Health Inc. is a company founded in 2016.

2

Funding Rounds

$63.4m

Money raised

Pfenex is a biotechnology company focused on protein therapies

Location:

Key people:

5

Funding Rounds

$32.9m

Money raised

FluGen is a vaccines & Adjuvants founded in 2007 by Paul Radspinner, Gabriele Neumann and Yoshihiro Kawaoka.

2

Funding Rounds

$15.5m

Money raised

OncoPep is a company developing immunotherapeutics for thetreatment of cancer founded in 2010 by Doris Peterkin, Ken Anderson and Marc Cohen.

3

Funding Rounds

$79.7m

Money raised

Synklino is an immunotoxin drug for cytomegalovirus in transplant recipients founded in 2017 by Thomas Kledal Ph.D., MBA , Mads Jeppesen Ph.D. and Mette Rosenkilde MD, Ph.D. .

1

Funding Rounds

$2.0m

Money raised

Vivaldi Biosciences is a biotechnology company developing live attenuated influenza vaccines founded in 2010 by Adolfo García-Sastre, Peter Palese and Elliott Kieff.

2

Funding Rounds

$24.0m

Money raised

A company focused on research, development and manufacture of vaccines against various infectious diseases

1

Funding Rounds

$8.0m

Money raised

Treos Bio is a cancer Vaccine Technology founded in 2013 by John Hautman.

Key people:

1

Funding Rounds

Enesi Pharma Limited is a solid Dose Vaccine Delivery founded in 2017.

2

Funding Rounds

$12.6m

Money raised

Oxford Vacmedix UK Limited is a cancer Vaccines founded in 2012 by Dr Shisong Jiang.

Key people:

2

Funding Rounds

$6.9m

Money raised

UbiVac is a vaccine / Immunotherapy founded in 2005 by Bernard A. Fox.

1

Funding Rounds

$55.0m

Money raised

ReViral is a biotechnology firm developing antiviral treatments for patients founded in 2011.

3

Funding Rounds

$22.3m

Money raised

Virus-like Particle Vaccines

1

Funding Rounds

$14.0m

Money raised

A company focused on the development of immunotherapeutics and preventative vaccines for fungal and bacterial disease

6

Funding Rounds

Vaccines

3

Funding Rounds

$60.0m

Money raised

A biotechnology company developing therapies and personalized diagnostics for celiac disease

2

Funding Rounds

$4.6m

Money raised

Scancell is a cancer vaccine founded in 1996 by Professor Lindy Durrant.

Key people:

1

Funding Rounds

$4.4m

Money raised

Etubics is a targeted immunotherapies and vaccine products founded in 2005 by Frank R. Jones.

2

Funding Rounds

$11.8m

Money raised

Piroutte Medical is a Boston-based company developing drug-delivery medical devices.

Key people:

2

Funding Rounds

$70.0m

Money raised

A company developing vaccines for flu, malaria, dengue, papillomavirus and respiratory syncytial virus

9

Funding Rounds

$102.9m

Money raised

ILIAD BIOTECHNOLOGIES, LLC is a pertussis Vaccine founded in 2012 by Keith Rubin, M.D..

Location:

Key people:

1

Funding Rounds

$144.0m

Money raised

Panacea Biotec is a differentiated generics, vaccines, biosimilars founded in 1994 by Soshil Kumar Jain.

2

Funding Rounds

$8.0m

Money raised

A company developing preventive and therapeutic vaccines for infectious diseases and oncolytic vaccines for cancer

Location:

Key people:

2

Funding Rounds

$4.8m

Money raised

3P Biopharmaceuticals is a manufacturing & Services founded in 2006.

1

Funding Rounds

$34.1m

Money raised

Affiris Ag is a therapeutic Vaccines founded in 2004 by Frank Mattner.

1

Funding Rounds

$60.0m

Money raised

Curevo Vaccine is a company founded in 2018.

4

Funding Rounds

$5.8m

Money raised

PathoVax is an HPV vaccine founded in 2014 by Joshua Wang.

Key people:

1

Funding Rounds

Sequoia Sciences is a company founded in 2012 by Gary Eldridge.

3

Funding Rounds

$100.0k

Money raised

Immunotherapies for Bacterial Infections

1

Funding Rounds

Abcombi Biosciences is a company founded in 2015 by Andrew Hill, Ph.D. .

2

Funding Rounds

Viral vector engineering, transduction enhancement and technology development

1

Funding Rounds

$2.5m

Money raised

Xeptiva Therapeutics is an innovative biotech that develops novel therapies for the veterinary market

Location:

Key people:

1

Funding Rounds

Integrated BioTherapeutics is a vaccines, Biologics, Monoclonals founded in 2009 by M. Javad Aman.

1

Funding Rounds

$3.0m

Money raised

Scandinavian Biopharma Holding is a various vaccines founded in 2010 by Björn Sjöstrand.

Location:

Key people:

1

Funding Rounds

Cytuvax is a vaccine Adjuvant founded by René Vleugels, PhD.

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