69 Best Vaccine Startups to Watch in 2025

The Definitive Seedtable Ranking of Vaccine Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 86 start-ups with an aggregate funding of $3.3b. The average funding per company in this subset is $47.5m.

Last update to the database: Feb 18, 2025. See changelog.

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Ligandal logo

Ligandal

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

6

Funding Rounds

$4.6m

Money raised

Prokarium logo

Prokarium

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

6

Funding Rounds

$86.6m

Money raised

Vaxess Technologies logo

Vaxess Technologies

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

14

Funding Rounds

$87.2m

Money raised

Sanofi Pasteur logo

Sanofi Pasteur

Sanofi Pasteur is a manufacturer of vaccines and related products founded in 1914 by Marcel Mérieux.

1

Funding Rounds

$43.2m

Money raised

HelixNano logo

HelixNano

HelixNano is a Cambridge, Massachusetts-based biotechnology and artificial intelligence company founded in 2013 by Hannu Rajaniemi and Nikolai Eroshenko.

12

Funding Rounds

$2.8m

Money raised

Emergex Vaccines Holding Limited logo

Emergex Vaccines Holding Limited

Emergex aims to tackle the global threat of infectious disease by providing affordable and practical on-demand vaccine solutions.

2

Funding Rounds

$11.3m

Money raised

Codagenix logo

Codagenix

A biotechnology company developing live attenuated vaccines. It was founded in 2012 and is located in New York.

5

Funding Rounds

$26.8m

Money raised

SmartPharm Therapeutics logo

SmartPharm Therapeutics

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

1

Funding Rounds

$10.5m

Money raised

CaroGen logo

CaroGen

CaroGen is an immunotherapy company that develops vaccine candidates that target hepatitis B and C, as well as other viral agents.

1

Funding Rounds

$150.0k

Money raised

Translate Bio logo

Translate Bio

Translate Bio is a clinical-stage mRNA therapeutics company developing medicines to treat diseases caused by protein or gene dysfunction and vaccines against infectious disease pathogens.

6

Funding Rounds

$227.7m

Money raised

SpyBiotech logo

SpyBiotech

A biomedical company in United Kingdom that develops vaccines and vaccine development technology

2

Funding Rounds

$37.5m

Money raised

Themis Bioscience logo

Themis Bioscience

A biotechnology company developing immune-modulation therapies for infectious diseases and cancer leveraging its technology platform and understanding of immune system mechanisms. It was founded in 2009 and is located in Vienna, Austria.

3

Funding Rounds

$68.0m

Money raised

Swiftscale Biologics logo

Swiftscale Biologics

Synthetic biology company developing vaccines and therapeutics using cell-free biology technology

2

Funding Rounds

$10.5m

Money raised

Meissa Vaccines logo

Meissa Vaccines

A pharmaceutical company focused on advancement of unmet vaccines against viruses that cause serious human diseases such as respiratory syncytial virus (RSV). Meissa Vaccines applies their platform technology for viral genetic engineering to multiple pathogens.

5

Funding Rounds

$72.3m

Money raised

EpiVax (company) logo

EpiVax (company)

A computational immunology and vaccine development company based in Providence, Rhode Island. It was founded in 1998.

9

Funding Rounds

$4.3m

Money raised

DCPrime logo

DCPrime

DCPrime is a biotechnology company developing cancer immunotherapies.

5

Funding Rounds

$26.0m

Money raised

Immunomic Therapeutics logo

Immunomic Therapeutics

A biotechnology company developing nucleic acid immunotherapy platform and protein based vaccines

2

Funding Rounds

$60.6m

Money raised

Kernal Biologics logo

Kernal Biologics

Cambridge, MA-based company developing targeted mRNA therapeutics for cancer and other diseases.

3

Funding Rounds

$50.6m

Money raised

Southern Research logo

Southern Research

A non-profit organization with a focus on scientific and engineering research. It was founded in 1941 and is located in Birmingham, Alabama.

2

Funding Rounds

$8.7m

Money raised

Diadem Biotherapeutics logo

Diadem Biotherapeutics

Biotherapeutics company focused on medicines for chronic inflammation, metabolic disease and autoimmune disease

1

Funding Rounds

Stemirna Therapeutics logo

Stemirna Therapeutics

Stemirna Therapeutics is an mRNA therapeutics and nanoparticle formulation company in China focused on treatments for cancer, infectious diseases and rare diseases.

1

Funding Rounds

$14.2m

Money raised

Vaxxas logo

Vaxxas

Vaxxas is commercializing a novel vaccination technology that dramatically enhances the performance of existing and next-generation vaccines.

1

Funding Rounds

$22.8m

Money raised

Osivax logo

Osivax

A clinical stage biotechnology company in France that focuses on developing a pipeline of vaccines and immunotherapies.

5

Funding Rounds

$26.4m

Money raised

Flaskworks logo

Flaskworks

An operator of a biotechnology company in Massachusetts that focuses on improving the manufacture of immuno-therapeutics and dendritic cell-based vaccines.

2

Funding Rounds

$950.0k

Money raised

ISA Pharmaceuticals logo

ISA Pharmaceuticals

ISA Pharmaceuticals is a synthetic therapeutic vaccines founded in 2004 by Cornelius Melief.

3

Funding Rounds

$61.4m

Money raised

Secfi logo

Secfi

Secfi is the pre-wealth advisor for startup employees. Figuring out what to do with your equity-based compensation is complicated and expensive and is therefore ignored and neglected. Secfi makes handling startup equity compensation simple and affordable. We build technology that helps employees make the right decisions for their equity compensation. By addressing their biggest concerns they can spend time on things they love doing most. We are hiring! Find out more at https://www.secfi.com/careers/

6

Funding Rounds

$714.0m

Money raised

Affinivax logo

Affinivax

Vaccine Discovery Technology Affinivax is a biopharmaceutical company developing vaccines that target infectious diseases.

3

Funding Rounds

$348.5m

Money raised

Immunophotonics logo

Immunophotonics

Immunophotonics is a company developing immunotherapy-based treatments for cancer founded in 2012 by Lu Alleruzzo.

7

Funding Rounds

$24.5m

Money raised

Bharat Biotech logo

Bharat Biotech

Bharat Biotech is an Indian vaccine manufacturer and pharmaceutical company.

3

Funding Rounds

$141.0m

Money raised

ANA Therapeutics logo

ANA Therapeutics

ANA Therapeutics is a Foster City, California-based developer of a novel corona vaccine.

2

Funding Rounds

$5.0m

Money raised

EpiVax Oncology logo

EpiVax Oncology

EpiVax Oncology is a Providence, Rhode Island-based company founded by Gad Berdugo, Anne de Groot and Bill Martin.

3

Funding Rounds

$2.8m

Money raised

LabConnect logo

LabConnect

LabConnect provides comprehensive central lab services for clinical development programs including routine and complex laboratory testing for biopharmaceutical and CRO clients.

2

Funding Rounds

$49.0m

Money raised

Akshaya BIO logo

Akshaya BIO

Flexible platform vaccine technology designed to elicit both humoral and cellular immune responses in hosts

1

Funding Rounds

$7.5m

Money raised

X-Vax Technology logo

X-Vax Technology

Biotechnology company focused on developing vaccines for herpes.

1

Funding Rounds

$56.0m

Money raised

MinervaX logo

MinervaX

MinervaX is a Copenhagen-based company founded in 2010 by Per Fischer.

3

Funding Rounds

$65.1m

Money raised

Mazen Animal Health Inc. logo

Mazen Animal Health Inc.

Mazen Animal Health Inc. is a company founded in 2016.

3

Funding Rounds

$26.8m

Money raised

Pfenex logo

Pfenex

Pfenex is a biotechnology company focused on protein therapies

2

Funding Rounds

$63.4m

Money raised

FluGen logo

FluGen

FluGen is a vaccines & Adjuvants founded in 2007 by Paul Radspinner, Gabriele Neumann and Yoshihiro Kawaoka.

5

Funding Rounds

$32.9m

Money raised

OncoPep logo

OncoPep

OncoPep is a company developing immunotherapeutics for thetreatment of cancer founded in 2010 by Doris Peterkin, Ken Anderson and Marc Cohen.

2

Funding Rounds

$15.5m

Money raised

Synklino logo

Synklino

Synklino is an immunotoxin drug for cytomegalovirus in transplant recipients founded in 2017 by Thomas Kledal Ph.D., MBA , Mads Jeppesen Ph.D. and Mette Rosenkilde MD, Ph.D. .

3

Funding Rounds

$79.7m

Money raised

Vivaldi Biosciences logo

Vivaldi Biosciences

Vivaldi Biosciences is a biotechnology company developing live attenuated influenza vaccines founded in 2010 by Adolfo García-Sastre, Peter Palese and Elliott Kieff.

1

Funding Rounds

$2.0m

Money raised

PaxVax logo

PaxVax

A company focused on research, development and manufacture of vaccines against various infectious diseases

2

Funding Rounds

$24.0m

Money raised

Treos Bio logo

Treos Bio

Treos Bio is a cancer Vaccine Technology founded in 2013 by John Hautman.

1

Funding Rounds

$8.0m

Money raised

Enesi Pharma Limited logo

Enesi Pharma Limited

Enesi Pharma Limited is a solid Dose Vaccine Delivery founded in 2017.

1

Funding Rounds

Oxford Vacmedix UK Limited logo

Oxford Vacmedix UK Limited

Oxford Vacmedix UK Limited is a cancer Vaccines founded in 2012 by Dr Shisong Jiang.

2

Funding Rounds

$12.6m

Money raised

UbiVac logo

UbiVac

UbiVac is a vaccine / Immunotherapy founded in 2005 by Bernard A. Fox.

2

Funding Rounds

$6.9m

Money raised

PsiOxus Therapeutics logo

PsiOxus Therapeutics

PsiOxus Therapeutics is an oncolytic Vaccines founded in 2010 by Kerry Fisher.

1

Funding Rounds

$22.0m

Money raised

VLP Therapeutics logo

VLP Therapeutics

Virus-like Particle Vaccines

3

Funding Rounds

$22.3m

Money raised

NovaDigm Therapeutics logo

NovaDigm Therapeutics

A company focused on the development of immunotherapeutics and preventative vaccines for fungal and bacterial disease

1

Funding Rounds

$14.0m

Money raised

ImmusanT logo

ImmusanT

A biotechnology company developing therapies and personalized diagnostics for celiac disease

3

Funding Rounds

$60.0m

Money raised

Scancell logo

Scancell

Scancell is a cancer vaccine founded in 1996 by Professor Lindy Durrant.

2

Funding Rounds

$4.6m

Money raised

Etubics logo

Etubics

Etubics is a targeted immunotherapies and vaccine products founded in 2005 by Frank R. Jones.

1

Funding Rounds

$4.4m

Money raised

Virometix logo

Virometix

Vaccines

6

Funding Rounds

ReViral logo

ReViral

ReViral is a biotechnology firm developing antiviral treatments for patients founded in 2011.

1

Funding Rounds

$55.0m

Money raised

Pirouette Medical, Llc. logo

Pirouette Medical, Llc.

Piroutte Medical is a Boston-based company developing drug-delivery medical devices.

2

Funding Rounds

$11.8m

Money raised

VaxInnate logo

VaxInnate

A company developing vaccines for flu, malaria, dengue, papillomavirus and respiratory syncytial virus

2

Funding Rounds

$70.0m

Money raised

ILIAD BIOTECHNOLOGIES, LLC logo

ILIAD BIOTECHNOLOGIES, LLC

ILIAD BIOTECHNOLOGIES, LLC is a pertussis Vaccine founded in 2012 by Keith Rubin, M.D..

9

Funding Rounds

$102.9m

Money raised

Panacea Biotec logo

Panacea Biotec

Panacea Biotec is a differentiated generics, vaccines, biosimilars founded in 1994 by Soshil Kumar Jain.

1

Funding Rounds

$144.0m

Money raised

Profectus Biosciences logo

Profectus Biosciences

A company developing preventive and therapeutic vaccines for infectious diseases and oncolytic vaccines for cancer

2

Funding Rounds

$8.0m

Money raised

3P Biopharmaceuticals logo

3P Biopharmaceuticals

3P Biopharmaceuticals is a manufacturing & Services founded in 2006.

2

Funding Rounds

$4.8m

Money raised

Affiris Ag logo

Affiris Ag

Affiris Ag is a therapeutic Vaccines founded in 2004 by Frank Mattner.

1

Funding Rounds

$34.1m

Money raised

Curevo Vaccine logo

Curevo Vaccine

Curevo Vaccine is a company founded in 2018.

1

Funding Rounds

$60.0m

Money raised

PathoVax logo

PathoVax

PathoVax is an HPV vaccine founded in 2014 by Joshua Wang.

4

Funding Rounds

$5.8m

Money raised

Sequoia Sciences logo

Sequoia Sciences

Sequoia Sciences is a company founded in 2012 by Gary Eldridge.

1

Funding Rounds

Immunethep	 logo

Immunethep

Immunotherapies for Bacterial Infections

3

Funding Rounds

$100.0k

Money raised

Abcombi Biosciences logo

Abcombi Biosciences

Abcombi Biosciences is a company founded in 2015 by Andrew Hill, Ph.D. .

1

Funding Rounds

Sirion Biotechnology logo

Sirion Biotechnology

Viral vector engineering, transduction enhancement and technology development

2

Funding Rounds

Xeptiva Therapeutics logo

Xeptiva Therapeutics

Xeptiva Therapeutics is an innovative biotech that develops novel therapies for the veterinary market

1

Funding Rounds

$2.5m

Money raised

Integrated BioTherapeutics logo

Integrated BioTherapeutics

Integrated BioTherapeutics is a vaccines, Biologics, Monoclonals founded in 2009 by M. Javad Aman.

1

Funding Rounds