69 Best Synthetic Biology Startups to Watch in 2025

The Definitive Seedtable Ranking of Synthetic Biology Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 261 start-ups with an aggregate funding of $15.3b. The average funding per company in this subset is $221.4m.

Last update to the database: Feb 18, 2025. See changelog.

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15

Funding Rounds

$140.4m

Money raised

Synthace is a software company based out of London, UK, building automation software that gives biologists the ability to control and analyze the performance of lab hardware.

5

Funding Rounds

$263.1m

Money raised

Mammoth Biosciences is an American company based in San Francisco founded on June 1, 2017. Mammoth Biosciences uses CRISPR technology to develop bio-sensing technologies for diagnostics in industries such as healthcare, agriculture, manufacturing, and forensics and genome editing therapeutics.

5

Funding Rounds

$72.2m

Money raised

Arzeda is a biotechnology and software company designing custom microorganisms for industrial applications through computational enzyme design, protein optimization, and metabolic engineering.

Key people:

1

Funding Rounds

$50.0k

Money raised

Pembient uses advances in biotechnology to fabricate horn and other wildlife products to combat the threat to endangered species.

11

Funding Rounds

$1.9b

Money raised

Impossible Foods is a plant-based meat company making meat and dairy products that are made to look and feel like animal products by manufacturing heme, the oxygen binding molecule found in blood, using engineered yeast grown in bioreactors.

5

Funding Rounds

$236.7m

Money raised

A genetic medicine company that build data platforms using synthetic biology, artificial intelligence and genetic medicine for the development of medical therapies.

Key people:

8

Funding Rounds

$406.4m

Money raised

Bolt Threads is a biotechnology company that makes high performance fabrics and materials using biology.

5

Funding Rounds

$5.1m

Money raised

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

Location:

Key people:

7

Funding Rounds

$711.5m

Money raised

Perfect Day Foods (formerly Muufri) engineered yeast capable of producing the proteins found in cows milk. They use these proteins to make their own line of animal-free dairy products.

Key people:

2

Funding Rounds

$15.6m

Money raised

Protera is a biotechnology company that works with protein engineering to address challenges in food, agriculture, the environment, and human health.

Location:

Key people:

9

Funding Rounds

$20.3m

Money raised

New Wave Foods is a biotechnology company developing plant-based shellfish food products. The company is based out of San Francisco, California and was founded in 2015 by Dominique Barnes and Michelle Wolf.

1

Funding Rounds

$12.5m

Money raised

A bio-based chemical manufacturer focusing on human and animal nutrition, health, and materials markets.

7

Funding Rounds

$83.0m

Money raised

Molecular Assemblies, Inc. is an enzymatic DNA synthesis technology founded in 2013 by Curt Becker, Bill Efcavitch and William Efcavitch.

4

Funding Rounds

$390.0m

Money raised

An Israeli startup company that is working to make sustainable "animal-free" cell-based meat products available at the local level by adapting the distributed manufacturing model

Key people:

8

Funding Rounds

$220.0m

Money raised

Just, Inc. (formerly known as Hampton Creek) is a food technology company developing and selling plant based food products around the world.

Location:

Key people:

4

Funding Rounds

$119.8m

Money raised

Aleph Farms is an Israeli cellular agriculture start-up founded by Didier Toubia and Shulamit Levenberg in 2017 developing technologies for culturing meat products into 3D structures.

Location:

Key people:

6

Funding Rounds

$168.0m

Money raised

Developer of fully interactive advanced lab simulations designed to create scalable science training software. The company's simulations offer a virtual laboratory based on mathematical algorithms that support open-ended investigations along with molecular three-dimension animations, quiz questions, and background theory.

4

Funding Rounds

$580.8m

Money raised

Upside Foods is a San Francisco-based company making cultured meat products. The company was founded by Uma Valeti, Nicholas Genovese, and Will Clem.

4

Funding Rounds

$725.0k

Money raised

Pheronym is a biotechnology company based out of Davis, California, which makes pheromones that control agricultural pests and can be used as a replacement for toxic pesticides.

Location:

Key people:

21

Funding Rounds

$1.9b

Money raised

Apeel Sciences is a company that develops treatments to prevent spoilage of fruits and vegetables using molecules naturally found in peels, which maintain moisture and keep out oxygen.

7

Funding Rounds

$63.3m

Money raised

Catalog is a Boston, Massachusetts-based company developing a platform for DNA-based digital data storage.

1

Funding Rounds

A Canadian food biotech company focused on the development of hypoallergenic peanuts

9

Funding Rounds

$331.1m

Money raised

Modern Meadow is a biotechnology company using cellular agriculture and biofabrication to manufacture bioleather, "Zoa", out of cultured animal free collagen mixed with natural and man made materials.

2

Funding Rounds

$3.4m

Money raised

Chai Biotechnologies (also known as Chai and Chai Bio) is a biotechnology company building real-time PCR, qPCR and devices that detect pathogens, speciate meat and genotype DNA.

2

Funding Rounds

$14.6m

Money raised

A biotechnology company that has built a robotic cloud lab which allows on-demand services for biology laboratories.

Key people:

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

10

Funding Rounds

$635.4m

Money raised

Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.

Location:

Key people:

5

Funding Rounds

$104.5m

Money raised

A cellular agriculture company making fresh and frozen cultured seafood products.

Key people:

11

Funding Rounds

$256.5m

Money raised

Meatable is a cellular agriculture company making 100 percent clean meat products.

Location:

Key people:

3

Funding Rounds

$1.4m

Money raised

MicroSynbiotiX was a company developing cost-effective oral vaccines to combat aquaculture infections and improve global food security. It was acquired by Sundew in 2021.

Location:

Key people:

13

Funding Rounds

$386.6m

Money raised

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

7

Funding Rounds

$114.3m

Money raised

Geltor is a cellular agriculture company making essential proteins, such as collagen and gelatin, using microbes in their own bio-fermentation recombinant protein production facility.

Key people:

9

Funding Rounds

$474.1m

Money raised

Solugen is a speciality chemical manufacturing company developing aiming to replace petroleum-based chemicals with alternatives made from plant-based substitutes.

6

Funding Rounds

$138.2m

Money raised

Mosa Meat is a Dutch start-up company that makes and commercializes clean meat, meat made by growing animal cells directly rather than slaughtering animals.

Location:

Key people:

3

Funding Rounds

$21.5m

Money raised

RoosterBio is a biotechnology company located in Frederick, Maryland, founded by Jon Rowley in 2013 providing standardized stem cell products for R&D, clinical, and commercial use in the regenerative medicine industry.

8

Funding Rounds

$175.0m

Money raised

Viridos is applying synthetic biology to microalgae for the production of products that address climate change and sustainability. Viridos is focused on producing algal biofuels and other sustainable resources from algae.

11

Funding Rounds

$50.0m

Money raised

An industrial biotech company developing a commercial bioprocess for manufacturing bio-based malonic acid.

6

Funding Rounds

$88.0m

Money raised

Prellis Biologics is developing technology to build transplantable human organs and tissues.

Location:

Key people:

5

Funding Rounds

$191.8m

Money raised

The EVERY Company (formally Clara Foods) is a biotechnology company founded by two New Harvest community members David Anchel and Arturo Elizondo in 2014. The company is based out of San Francisco, California and manufactures animal- free proteins using using yeast bio-fermentation techniques fore use in food products.

13

Funding Rounds

$1.1b

Money raised

Spiber, Inc is a private biomaterials company using industrial biotechnology to develop silk.

5

Funding Rounds

$68.7m

Money raised

AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.

Key people:

5

Funding Rounds

$24.7m

Money raised

A-Alpha Bio is a startup that has built a platform technology and aims to speed up the development of new drugs.

Location:

Key people:

6

Funding Rounds

$129.3m

Money raised

AMSilk is a Munich-based synthetic biology company that produces fibers made from the same protein as spider silk.

Industries:

Location:

Key people:

7

Funding Rounds

$21.2m

Money raised

Wild Earth is a biotechnology company using cellular agriculture to produce high-protein pet food.

1

Funding Rounds

$32.0m

Money raised

Air Protein is a Berkeley-based biotechnology company producing protein with microorganisms that are fed carbon dioxide in a mission to replace animal agriculture.

9

Funding Rounds

$82.6m

Money raised

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

Location:

Key people:

9

Funding Rounds

$411.9m

Money raised

Benchling is a company based in San Francisco focusing on life science collaboration, both private and public, through creating cloud based software tools for digital DNA sequence editing, designing and running experiments, analyzing data, and sharing research.

Industries:

Location:

Key people:

2

Funding Rounds

$60.2k

Money raised

Visolis is a bioengineering and chemical processing company making sustainable and carbon-negative materials; headquartered in Berkeley, California.

Key people:

2

Funding Rounds

$3.2m

Money raised

SuperMeat is an Israeli biotechnology company, founded on December 15, 2015. SuperMeat is working to develop chicken meat products cultured from extracted chicken cells.

3

Funding Rounds

$60.0m

Money raised

Uncommon, formerly known as Higher Steaks, is a cellular agriculture company based in London, England founded in 2017 by Benjamina Bollag, Stephanie Wallis and David Hay working to develop pork and other meat products using cellular agriculture.

Key people:

8

Funding Rounds

$1.1b

Money raised

Pivot Bio is a company that creates technology that is focused on nitrogen fixation in cereal crops through microbes.It was founded in 2010 and is located in Berkeley, California.

8

Funding Rounds

$101.4m

Money raised

Synthetic biology company that uses AI, DNA synthesis, and robotics to discover biological molecules.

Location:

Key people:

3

Funding Rounds

$11.2m

Money raised

Cambrian Genomics is a biotechnology company developing technologies to synthesize DNA. The company is headquartered in San Francisco, California, and was founded in 2011.

6

Funding Rounds

$86.6m

Money raised

Prokarium is a biopharmaceutical company focused on developing vaccination and cancer immunotherapy solutions based on synthetic biology.

Location:

Key people:

14

Funding Rounds

$87.2m

Money raised

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

Location:

Key people:

8

Funding Rounds

$459.7m

Money raised

Silicon Valley-based genetic engineering startup.

Key people:

2

Funding Rounds

$22.8m

Money raised

Emerald Therapeutics is a biotechnology company located in San Fransisco, California, founded by Brian Frezza and DJ Klienbaum in 2010. Emerald Therapeutics offers cloud a based software and hardware platform that allows researchers to remotely perform automated scientific laboratory experiments.

4

Funding Rounds

$24.9m

Money raised

Riffyn is a company that develops cloud-based R&D software that they call the Scientific Development Environment (SDE). The SDE is a computer aided design (CAD) platform allowing users to visually design processes and experiments, execute experiments, collect and analyze data in real-time using machine learning, and share results and protocols eas

2

Funding Rounds

$4.5m

Money raised

Cellink AB is a biotechnology research company based in Gothenburg.

6

Funding Rounds

$265.4m

Money raised

A New Zealand industrial biotechnology company developing a gas fermentation platform for converting concentrated industrial emissions into valuable chemicals.

4

Funding Rounds

$84.5m

Money raised

SCiFi Foods (formerly Artemys Foods) is a company that makes and provides meat that is animal-free

5

Funding Rounds

$20.4m

Money raised

Shiok Meats is a Singapore-based cellular agriculture company focusing on making cultured seafood.

Location:

Key people:

9

Funding Rounds

$262.0m

Money raised

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

4

Funding Rounds

$153.5m

Money raised

Sherlock Biosciences is a Cambridge, Massachusetts-based company founded in 2019 by David R. Walt, Rahul Dhanda, Feng Zhang, Jim Collins, Deborah Hung, Jonathan Gootenberg, Omar Abudayyeh, Pardis Sabeti and Todd Golub.

3

Funding Rounds

$8.6m

Money raised

Nebula Genomics is a genetics company developing a platform for individuals to get their personal genome sequenced, and then enable them to store and control that information through cryptographic encryption on the blockchain.

Key people:

4

Funding Rounds

$49.3m

Money raised

Sphere Fluidics is a company commercializing single cell analysis systems founded in 2010 by Wilhelm Huck.

12

Funding Rounds

$2.8m

Money raised

HelixNano is a Cambridge, Massachusetts-based biotechnology and artificial intelligence company founded in 2013 by Hannu Rajaniemi and Nikolai Eroshenko.

4

Funding Rounds

$119.5m

Money raised

Wild Type is a San Francisco based company producing meat products like salmon using cellular agriculture lab techniques.

Key people:

6

Funding Rounds

$21.8m

Money raised

Aromyx is a biotechnology company developing a biosensor for human tase and olfactory receptors.

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