69 Best Regenerative Medicine Startups to Watch in 2025

The Definitive Seedtable Ranking of Regenerative Medicine Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 285 start-ups with an aggregate funding of $5.7b. The average funding per company in this subset is $82.6m.

Last update to the database: Feb 18, 2025. See changelog.

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Mammoth Biosciences logo

Mammoth Biosciences

Mammoth Biosciences is an American company based in San Francisco founded on June 1, 2017. Mammoth Biosciences uses CRISPR technology to develop bio-sensing technologies for diagnostics in industries such as healthcare, agriculture, manufacturing, and forensics and genome editing therapeutics.

5

Funding Rounds

$263.1m

Money raised

Senti Biosciences logo

Senti Biosciences

Senti Biosciences is a synthetic biology company.

2

Funding Rounds

$158.0m

Money raised

BlueRock Therapeutics logo

BlueRock Therapeutics

A biotechnology company developing engineered cell therapies for treating diseases in neurology, cardiology and autoimmunity.

1

Funding Rounds

$225.0m

Money raised

RoosterBio logo

RoosterBio

RoosterBio is a biotechnology company located in Frederick, Maryland, founded by Jon Rowley in 2013 providing standardized stem cell products for R&D, clinical, and commercial use in the regenerative medicine industry.

3

Funding Rounds

$21.5m

Money raised

Orig3n logo

Orig3n

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

5

Funding Rounds

$111.8m

Money raised

Scribe Therapeutics logo

Scribe Therapeutics

Scribe Therapeutics develops molecular engineering solutions for CRISPR-based genetic medicine.

2

Funding Rounds

$120.0m

Money raised

Prellis Biologics logo

Prellis Biologics

Prellis Biologics is developing technology to build transplantable human organs and tissues.

6

Funding Rounds

$88.0m

Money raised

Kuur Therapeutics logo

Kuur Therapeutics

Kuur Therapeutics focuses on the development of CAR-NKT cell therapies platform for applications in cancer treatment.

6

Funding Rounds

$190.5m

Money raised

Locus Biosciences logo

Locus Biosciences

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

8

Funding Rounds

$117.5m

Money raised

Promethera Biosciences logo

Promethera Biosciences

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

5

Funding Rounds

$103.1m

Money raised

ViaCyte logo

ViaCyte

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

16

Funding Rounds

$328.8m

Money raised

Cell Design Labs logo

Cell Design Labs

A biotechnology company founded in 2015 which operates as a subsidiary of Gilead Sciences and Kite Pharma. The company developed a platform for custom cell engineering called synNotch to be used for anticancer therapies. Their system can also be used to develop cell-based therapies for autoimmune and degenerative disorders.

1

Funding Rounds

$34.4m

Money raised

Stemline Therapeutics logo

Stemline Therapeutics

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

2

Funding Rounds

$13.8m

Money raised

EpiBone logo

EpiBone

EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.

1

Funding Rounds

Synthego logo

Synthego

Silicon Valley-based genetic engineering startup.

8

Funding Rounds

$459.7m

Money raised

Bionic logo

Bionic

Bionic is a company founded in 2019 by Idan Ninyo.

2

Funding Rounds

$82.0m

Money raised

EdiGene logo

EdiGene

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

9

Funding Rounds

$262.0m

Money raised

Obsidian Therapeutics logo

Obsidian Therapeutics

Develops novel cell and gene therapies with pharmacologic operating systems.

2

Funding Rounds

$164.5m

Money raised

3T Biosciences logo

3T Biosciences

3T Biosciences is a biotechnology company developing immunotherapies.

3

Funding Rounds

$52.0m

Money raised

Multiply Labs logo

Multiply Labs

Company manufacturing 3d printed pharmaceuticals based in San Francisco, CA

4

Funding Rounds

$30.0m

Money raised

SmartPharm Therapeutics logo

SmartPharm Therapeutics

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

1

Funding Rounds

$10.5m

Money raised

Betalin Therapeutics logo

Betalin Therapeutics

Biological micro-pancreas for insulin-dependent diabetics company

4

Funding Rounds

$5.1m

Money raised

Integrated DNA Technologies logo

Integrated DNA Technologies

Integrated DNA Technologies is a Coralville, Iowa-based company founded in 1987.

1

Funding Rounds

Bit.bio logo

Bit.bio

Bit.bio is a biotechnology company that aims to operate within human cells through means of coding and biology.

3

Funding Rounds

$183.9m

Money raised

Oisin Biotechnologies logo

Oisin Biotechnologies

Oisin develops anti-aging treatments that target and remove senescent cells, a type of damaged cell that is unable to divide, accumulates during aging and contribute to age-related diseases.

4

Funding Rounds

$7.1m

Money raised

Dyno Therapeutics logo

Dyno Therapeutics

Dyno Therapeutics is a company based in Cambridge, Massachusetts applying artificial intelligence to gene therapy, focused on adeno-associated virus capsid engineering.

3

Funding Rounds

$109.0m

Money raised

Tmunity Therapeutics logo

Tmunity Therapeutics

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

5

Funding Rounds

$425.0m

Money raised

Aegle Therapeutics logo

Aegle Therapeutics

Aegle Therapeutics Corporation, a regenerative medicine company isolating extracellular vesicles ("EVs") from allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat severe dermatological conditions, including burns and epidermolysis bullosa (“EB”).

5

Funding Rounds

$14.5m

Money raised

Juventus Therapeutics logo

Juventus Therapeutics

Juventas Therapeutics is a biotechnology company founded in 2007 that is headquartered in Cleveland, Ohio developing a pipeline of regenerative therapies to treat life-threatening diseases.

4

Funding Rounds

$46.7m

Money raised

Allevi logo

Allevi

Allevi, formerly known as BioBots, is a technology company making 3 dimensional bioprinters and bioinks for their printers. The company was founded in 2014 and located in Philadelphia, Pennsylvania.

1

Funding Rounds

$2.0m

Money raised

OncoSenX logo

OncoSenX

OncoSenX is a spinout company of Oisin Biotechnologies, formed to develop programmable suicide gene therapy to kill cancerous cells.

5

Funding Rounds

$19.7m

Money raised

BioAesthetics logo

BioAesthetics

A biotechnology company with a focus on developing medical solutions with biomaterial. It was founded in 2015 and is located in Durham, North Carolina.

2

Funding Rounds

$6.2m

Money raised

Tempo Therapeutics logo

Tempo Therapeutics

Tempo Therapeutics is an interventional biomaterials for regenerative medicine company founded by Westbrook Weaver.

1

Funding Rounds

$3.9m

Money raised

Celdara Medical logo

Celdara Medical

Celdara Medical is a biotechnology company helping turn academic innovations into medical products.

1

Funding Rounds

$1.7m

Money raised

Eureka Therapeutics, Inc logo

Eureka Therapeutics, Inc

Eureka Therapeutics is a biotechnology company developing immunotherapies for the treatment of cancer.

2

Funding Rounds

$105.0m

Money raised

Spiderwort logo

Spiderwort

A biotechnology company using tissue engineering to create biomaterials for repairing and regenerating the human body.

1

Funding Rounds

$13.2m

Money raised

Kiadis Pharma logo

Kiadis Pharma

Kiadis Pharma is a biotechnology company developing stem cell regenerative medicine treatments for blood cancers and blood disorders.

1

Funding Rounds

$12.8m

Money raised

Novadip Biosciences logo

Novadip Biosciences

Novadip Biosciences is a biotechnology company developing regenerative medicines using stem cells.

2

Funding Rounds

$82.0m

Money raised

GentiBio logo

GentiBio

GentiBio, Inc. is a biotherapeutics company developing engineered regulatory T cells (Tregs) therapies for immunology.

2

Funding Rounds

$177.0m

Money raised

Gadeta logo

Gadeta

Gadeta is a biotechnology company developing immunotherapies for treating cancer.

1

Funding Rounds

$7.0m

Money raised

Coave Therapeutics logo

Coave Therapeutics

Coave Therapeutics is a genetic medicines developer founded in 2014.

6

Funding Rounds

$94.2m

Money raised

Kyverna Therapeutics logo

Kyverna Therapeutics

Kyverna is a cell therapy company engineering a new class of curative living medicines for inflammatory and autoimmune diseases.

2

Funding Rounds

$110.0m

Money raised

Ossium Health logo

Ossium Health

Ossium is building the world's first bone marrow bank to treat blood cancers, improve organ transplantation, and repair damage

3

Funding Rounds

$73.4m

Money raised

Immusoft logo

Immusoft

Immusoft is a biotechnology company developing a platform for the insertion of therapeutic genes into immune cells for the treatment of a variety of genetic diseases.

11

Funding Rounds

$37.9m

Money raised

Locate Bio logo

Locate Bio

Locate Bio is a biotechnology developing cell and gene therapies for treating damaged tissues and organs.

9

Funding Rounds

$59.1m

Money raised

Trailhead Biosystems logo

Trailhead Biosystems

Trailhead Biosystems is a biotechnology company developing cell therapy products.

3

Funding Rounds

$17.2m

Money raised

STEMCELL Technologies logo

STEMCELL Technologies

A Canadian biotechnology company that develops specialty cell culture media, cell isolation systems and accessory products for life science research.

1

Funding Rounds

$15.0m

Money raised

Ablitech, Inc. logo

Ablitech, Inc.

A biotechnology company founded in 2006 and based in Baltimore, MD, that develops polymers to deliver DNA and RNA therapeutics.

1

Funding Rounds

$2.0m

Money raised

Abcuro, Inc. logo

Abcuro, Inc.

Abcuro develops immunotherapies to treat autoimmunity and cancer.

4

Funding Rounds

$72.3m

Money raised

Carisma Therapeutics logo

Carisma Therapeutics

Carisma Therapeutics is a biotechnology company founded in 2016 to bring the potheyr of adoptive cellular immunotherapy to solid tumor patients through a novel platform using chimeric antigen receptor macrophages (CARMA).

2

Funding Rounds

$112.0m

Money raised

Asimov logo

Asimov

Asimov is a startup that programs living cells with genetic circuits.

1

Funding Rounds

$4.7m

Money raised

Refuge Biotechnologies logo

Refuge Biotechnologies

Refuge Biotechnologies is a biotechnology company that uses CRISPR and cell therapy technologies for treating cancer.

2

Funding Rounds

$33.9m

Money raised

Emody logo

Emody

Embody, Inc. is a regenerative medicine company focused on the development and commercialization of implantable medical devices to address unmet needs in soft tissue restoration and regeneration.

3

Funding Rounds

$15.4m

Money raised

American Gene Technologies logo

American Gene Technologies

AGT is developing and commercializing gene and cell therapy and targeting major diseases, including HIV/AIDS, Phenylketonuria (PKU) and Hepatocellular carcinoma.

4

Funding Rounds

$6.0m

Money raised

Argonaut Therapeutics logo

Argonaut Therapeutics

Precision therapeutics company developing epigenetic therapies that target arginine methylation in cancer.

2

Funding Rounds

$2.6m

Money raised

Mekonos logo

Mekonos

Mekonos is a company that creates cell-engineering platforms

3

Funding Rounds

$31.0m

Money raised

A2 Biotherapeutics, Inc logo

A2 Biotherapeutics, Inc

A2 Biotherapeutics, Inc. is a biotechnology research company developing T-cell therapies designed to attack solid tumors while sparing normal cells

1

Funding Rounds

$71.5m

Money raised

TeVideo Biodevices logo

TeVideo Biodevices

TeVido Biodevices is a biotechnology company developing cell therapy products for restoring lost skin pigment.

4

Funding Rounds

$1.4m

Money raised

PACT Pharma logo

PACT Pharma

PACT Pharma is synthesizing neo-epitope targeted T cells and producing a personalized adoptive cell therapy designed to benefit each cancer patient.

3

Funding Rounds

$200.0m

Money raised

StemBioSys logo

StemBioSys

StemBioSys is a biotechnology company developing regenerative medicines using stem cells.

1

Funding Rounds

$1.5m

Money raised

Excision BioTherapeutics logo

Excision BioTherapeutics

Excision BioTherapeutics is a company founded in 2015 and headquartered in Philadelphia.

3

Funding Rounds

$70.8m

Money raised

Mogrify logo

Mogrify

Mogrify is developing tailored cellular conversions that power future cell therapies.

8

Funding Rounds

$84.5m

Money raised

Spark Therapeutics logo

Spark Therapeutics

Spark Therapeutics is a Philadelphia-based therapeutics and biotechnology company founded in 2013.

2

Funding Rounds

$122.8m

Money raised

Tactiva Therapeutics logo

Tactiva Therapeutics

Tactiva Therapeutics is a biotechnology company developing cancer immunotherapies.

1

Funding Rounds

$35.0m

Money raised

Stemedica Cell Technologies logo

Stemedica Cell Technologies

Stemedica Cell Technologies is a biopharmaceutical company developing and manufacturing adult stem cells and stem cell factors for research institutions and hospitals for pre-clinical and clinical studies

1

Funding Rounds

$22.0m

Money raised

Diadem Biotherapeutics logo

Diadem Biotherapeutics

Biotherapeutics company focused on medicines for chronic inflammation, metabolic disease and autoimmune disease

1

Funding Rounds

Encoded Therapeutics, Inc. logo

Encoded Therapeutics, Inc.

Encoded Therapeutics is a developer of genomics-driven precision medicine targeting and treating genetic diseases and disorders.

4

Funding Rounds

$343.1m

Money raised

Cytonus Therapeutics logo

Cytonus Therapeutics

Cytonus Therapeutics is a biotechnology company developing adaptive cellular therapies for treating immune-oncology and inflammatory diseases.

4

Funding Rounds

$2.6m

Money raised

Universal Cells logo

Universal Cells

Universal Cells is a biotechnology company developing regenerative medicine using stem cells.

1

Funding Rounds

$60.0k

Money raised