62 Best Genome Editing Startups to Watch in 2025

The Definitive Seedtable Ranking of Genome Editing Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 62 start-ups with an aggregate funding of $8.1b. The average funding per company in this subset is $131.3m.

Last update to the database: Feb 18, 2025. See changelog.

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5

Funding Rounds

$263.1m

Money raised

Mammoth Biosciences is an American company based in San Francisco founded on June 1, 2017. Mammoth Biosciences uses CRISPR technology to develop bio-sensing technologies for diagnostics in industries such as healthcare, agriculture, manufacturing, and forensics and genome editing therapeutics.

2

Funding Rounds

$120.0m

Money raised

Scribe Therapeutics develops molecular engineering solutions for CRISPR-based genetic medicine.

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

16

Funding Rounds

$328.8m

Money raised

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

9

Funding Rounds

$82.6m

Money raised

Biotherapeautics company founded in 2014 and based in Paris that uses proprietary methods in synthetic biology, protein and genome engineering to produce Eligobiotics, products which intervene with the microbiome as diagnostics, antimicrobials and modulators of host-microbiome interactions.

Location:

Key people:

6

Funding Rounds

$4.6m

Money raised

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

8

Funding Rounds

$459.7m

Money raised

Silicon Valley-based genetic engineering startup.

Key people:

9

Funding Rounds

$262.0m

Money raised

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

4

Funding Rounds

$153.5m

Money raised

Sherlock Biosciences is a Cambridge, Massachusetts-based company founded in 2019 by David R. Walt, Rahul Dhanda, Feng Zhang, Jim Collins, Deborah Hung, Jonathan Gootenberg, Omar Abudayyeh, Pardis Sabeti and Todd Golub.

5

Funding Rounds

$425.0m

Money raised

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

6

Funding Rounds

$41.3m

Money raised

Beta Hatch is an insect protein for farming company founded in 2015 by Virginia Emery.

Key people:

7

Funding Rounds

$31.4m

Money raised

Oxford Genetics, also known as Oxgene, is a synthetic biology company specializing in DNA design, protein expression optimization and cell line development technologies and services.

13

Funding Rounds

$677.0m

Money raised

A gene editing technology company founded in 2015 and based in Boulder, CO, USA.

5

Funding Rounds

$30.9m

Money raised

Horizon Discovery is a company that offers gene editing, CRO, and diagnostics services

Key people:

2

Funding Rounds

$100.0m

Money raised

Snipr Biome is a synthetic biology company using CRISPR to make products for the microbiome.

3

Funding Rounds

$600.0k

Money raised

Caspr Biotech is developing a CRISPR-based platform for rapid diagnostic systems for viruses, bacteria and genetic mutations

2

Funding Rounds

$110.0m

Money raised

Kyverna is a cell therapy company engineering a new class of curative living medicines for inflammatory and autoimmune diseases.

2

Funding Rounds

$33.9m

Money raised

Refuge Biotechnologies is a biotechnology company that uses CRISPR and cell therapy technologies for treating cancer.

Key people:

11

Funding Rounds

$67.4m

Money raised

Recombinetics is a biotechnology company that uses gene editing for agriculture and medicine

3

Funding Rounds

$200.0m

Money raised

PACT Pharma is synthesizing neo-epitope targeted T cells and producing a personalized adoptive cell therapy designed to benefit each cancer patient.

3

Funding Rounds

$70.8m

Money raised

Excision BioTherapeutics is a company founded in 2015 and headquartered in Philadelphia.

3

Funding Rounds

$3.5m

Money raised

enEvolv is a Medford, Massachusetts-based biological product manufacturer.

1

Funding Rounds

$215.0m

Money raised

Arbor Technologies is a company in Cambridge, MA, focusing on biodiscovery using machine learning, genome sequencing, gene synthesis and high-throughput screening.

2

Funding Rounds

$5.2m

Money raised

Agragene develops sterile male insects to replace chemical pesticides for the control of crop pests

Key people:

3

Funding Rounds

$45.5m

Money raised

JumpCode Genomics develops NGS solutions for the oncology, infectious disease, basic research, and consumer genomics fields.

Key people:

2

Funding Rounds

$115.0m

Money raised

Pairwise uses CRISPR, gene editing and natural diversity in agricultural crops to address global food challenges. The company is working to develop new varieties of crops.

3

Funding Rounds

$34.5m

Money raised

GenEdit develops technology for gene editing.

Key people:

2

Funding Rounds

$156.0m

Money raised

KSQ Therapeutics is a Cambridge, Massachusetts-based company in the pharmaceuticals industry founded in 2015.

2

Funding Rounds

$97.5m

Money raised

SparingVision is a retinal Gene Therapy Treatments founded by Jose alain sahel.

2

Funding Rounds

$7.4m

Money raised

Blue Heron Biotechnology Inc is company that provides synthetic DNA sequences and related services to the pharmaceutical and biotechnology companies

5

Funding Rounds

$298.0m

Money raised

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

4

Funding Rounds

$210.6m

Money raised

Locanabio is a San Diego, California-based biotechnology company developing RNA-targeting gene therapies.

Location:

Key people:

4

Funding Rounds

$38.5m

Money raised

Tropic Biosciences is a genome editing company founded in 2016 by Gilad Gershon.

Location:

Key people:

4

Funding Rounds

$7.8m

Money raised

Canopy Biosciences is a company that aims to increase the commercialization of life science reagent tools and services via in-licensing key technologies.

Key people:

1

Funding Rounds

Biotech company developing technologies to improve efficiency and safety of CRISPR-Cas gene editing through anti-CRISPR proteins, also known as Acr proteins

2

Funding Rounds

$5.8m

Money raised

Phytoform Labs is a biotechnology company.

Location:

Key people:

2

Funding Rounds

$695.0m

Money raised

ElevateBio is a company founded by Vikas Sinha, David Hallal and Melissa Carpenter.

1

Funding Rounds

$172.0m

Money raised

Wugen is an off-the-shelf Cell Therapies for Cancer founded by Matthew Cooper, Todd Fehniger, Melissa Berrien-Elliott and John DiPersio.

2

Funding Rounds

$34.0m

Money raised

CureGenetics is a biotechnology company using CRISPR to develop cellular therapies, gene therapies, and molecular diagnostic tools.

Location:

Key people:

3

Funding Rounds

$16.1m

Money raised

Integra Therapeutics is a biotech company engineering the next generation of gene writing tools to cure genetic diseases.

2

Funding Rounds

$260.0m

Money raised

Colossal Biosciences is a biotechnology and genetic engineering company that uses gene editing technology to de-extinct species.

1

Funding Rounds

$70.5m

Money raised

Ensoma, Inc. is an in vivo Gene Therapy founded in 2019.

2

Funding Rounds

$60.0m

Money raised

IASO Biotherapeutics is a biopharmaceutical company focused on the development of cell therapies in the field of oncology.

4

Funding Rounds

$89.0m

Money raised

Latch Bio is a San Francisco-based company founded by Kyle Giffin, Kenny Workman and Alfredo Andere.

Location:

Key people:

3

Funding Rounds

$117.5m

Money raised

Spotlight Therapeutics is an in vivo Gene Editing founded in 2017 by Patrick Hsu, Alexander Marson and Jacob Corn.

1

Funding Rounds

$40.0m

Money raised

Watchmaker Genomics applies enzymology to enable applications for reading, writing and editing DNA.

Location:

Key people:

1

Funding Rounds

$1.6m

Money raised

Cultured Decadence is a Wisconsin-based cellular agriculture company using cell culture and tissue engineering technologies to make lobster meat directly from the animal's cells. The company was acquired by Upside Foods in January 2022.

2

Funding Rounds

$315.0m

Money raised

Prime Medicine is a gene Editing Technology founded in 2019 by David R. Liu.

Key people:

1

Funding Rounds

$14.0m

Money raised

Hui-Gene Therapeutics is a company founded in 2018 by Xuan Yao.

Location:

Key people:

2

Funding Rounds

$530.0m

Money raised

Tessera Therapeutics is a biotechnology company pioneering Gene Writing™ to drive advancements in genome engineering.

Key people:

2

Funding Rounds

$175.0m

Money raised

Metagenomi is a Gene-Edited Microbial Treatments.

2

Funding Rounds

$29.5m

Money raised

ONK Therapeutics is a natural Killer Cell Therapies founded in 2015.

2

Funding Rounds

$35.0m

Money raised

SeQure Dx is a diagnostics company specializing in gene-editing.

Key people:

1

Funding Rounds

$45.0m

Money raised

Proof Diagnostics is harnessing CRISPR technology to unlock powerful molecular diagnostics for all, starting with COVID-19 testing.

1

Funding Rounds

$175.0m

Money raised

Affini-T Therapeutics, Inc is a TCR Cell Therapy.

1

Funding Rounds

$87.0m

Money raised

Clade Therapeutics is a stem Cell Therapies founded by Jim Glasheen, Chad Cowan and Leandro Vetcher.

2

Funding Rounds

$30.0m

Money raised

Avectas is a Non-Viral Cell Manufacturing Technology.

1

Funding Rounds

$55.0m

Money raised

Epic Bio is a biotechnology company developing ultracompact therapies to modulate gene expression in vivo using the smallest known Cas protein, CasMINI.

1

Funding Rounds

$50.0m

Money raised

iECURE is a gene Editing Therapies.

1

Funding Rounds

$80.0m

Money raised

1

Funding Rounds

$4.0m

Money raised

CRISPRQC INC. is a quality Control for CRISPR founded in 2021.

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