62 Best Genome Editing Startups to Watch in 2025

The Definitive Seedtable Ranking of Genome Editing Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 62 start-ups with an aggregate funding of $8.1b. The average funding per company in this subset is $131.4m.

Last update to the database: Jun 3, 2025. See changelog.

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5

Funding Rounds

$263.1m

Money raised

Mammoth Biosciences is an American company based in San Francisco founded on June 1, 2017. Mammoth Biosciences uses CRISPR technology to develop bio-sensing technologies for diagnostics in industries such as healthcare, agriculture, manufacturing, and forensics and genome editing therapeutics.

2

Funding Rounds

$120.0m

Money raised

Scribe Therapeutics develops molecular engineering solutions for CRISPR-based genetic medicine.

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

10

Funding Rounds

$87.6m

Money raised

Eligo Bioscience is a developer of novel genetic medicines founded in 2014 by Timothy Lu, Xavier Duportet, Luciano Marraffini and David Bikard.

Location:

Key people:

16

Funding Rounds

$328.8m

Money raised

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

6

Funding Rounds

$4.6m

Money raised

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

8

Funding Rounds

$459.7m

Money raised

Silicon Valley-based genetic engineering startup.

Key people:

9

Funding Rounds

$262.0m

Money raised

A biotechnology company using genetic editing technologies to develop therapies for the treatment of cancer and genetic diseases.

4

Funding Rounds

$153.5m

Money raised

Sherlock Biosciences is a Cambridge, Massachusetts-based company founded in 2019 by David R. Walt, Rahul Dhanda, Feng Zhang, Jim Collins, Deborah Hung, Jonathan Gootenberg, Omar Abudayyeh, Pardis Sabeti and Todd Golub.

5

Funding Rounds

$425.0m

Money raised

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

6

Funding Rounds

$41.3m

Money raised

Beta Hatch is an insect protein for farming company founded in 2015 by Virginia Emery.

Key people:

7

Funding Rounds

$31.4m

Money raised

Oxford Genetics, also known as Oxgene, is a synthetic biology company specializing in DNA design, protein expression optimization and cell line development technologies and services.

13

Funding Rounds

$677.0m

Money raised

A gene editing technology company founded in 2015 and based in Boulder, CO, USA.

5

Funding Rounds

$30.9m

Money raised

Horizon Discovery is a company that offers gene editing, CRO, and diagnostics services

Key people:

2

Funding Rounds

$100.0m

Money raised

Snipr Biome is a synthetic biology company using CRISPR to make products for the microbiome.

3

Funding Rounds

$600.0k

Money raised

Caspr Biotech is developing a CRISPR-based platform for rapid diagnostic systems for viruses, bacteria and genetic mutations

2

Funding Rounds

$110.0m

Money raised

Kyverna is a cell therapy company engineering a new class of curative living medicines for inflammatory and autoimmune diseases.

2

Funding Rounds

$33.9m

Money raised

Refuge Biotechnologies is a biotechnology company that uses CRISPR and cell therapy technologies for treating cancer.

Key people:

11

Funding Rounds

$67.4m

Money raised

Recombinetics is a biotechnology company that uses gene editing for agriculture and medicine

3

Funding Rounds

$200.0m

Money raised

PACT Pharma is synthesizing neo-epitope targeted T cells and producing a personalized adoptive cell therapy designed to benefit each cancer patient.

3

Funding Rounds

$70.8m

Money raised

Excision BioTherapeutics is a company founded in 2015 and headquartered in Philadelphia.

3

Funding Rounds

$3.5m

Money raised

enEvolv is a Medford, Massachusetts-based biological product manufacturer.

1

Funding Rounds

$215.0m

Money raised

Arbor Technologies is a company in Cambridge, MA, focusing on biodiscovery using machine learning, genome sequencing, gene synthesis and high-throughput screening.

2

Funding Rounds

$5.2m

Money raised

Agragene develops sterile male insects to replace chemical pesticides for the control of crop pests

Key people:

3

Funding Rounds

$45.5m

Money raised

JumpCode Genomics develops NGS solutions for the oncology, infectious disease, basic research, and consumer genomics fields.

Key people:

2

Funding Rounds

$115.0m

Money raised

Pairwise uses CRISPR, gene editing and natural diversity in agricultural crops to address global food challenges. The company is working to develop new varieties of crops.

3

Funding Rounds

$34.5m

Money raised

GenEdit develops technology for gene editing.

Key people:

2

Funding Rounds

$156.0m

Money raised

KSQ Therapeutics is a Cambridge, Massachusetts-based company in the pharmaceuticals industry founded in 2015.

2

Funding Rounds

$97.5m

Money raised

SparingVision is a retinal Gene Therapy Treatments founded by Jose alain sahel.

2

Funding Rounds

$7.4m

Money raised

Blue Heron Biotechnology Inc is company that provides synthetic DNA sequences and related services to the pharmaceutical and biotechnology companies

5

Funding Rounds

$298.0m

Money raised

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

4

Funding Rounds

$210.6m

Money raised

Locanabio is a San Diego, California-based biotechnology company developing RNA-targeting gene therapies.

Location:

Key people:

4

Funding Rounds

$38.5m

Money raised

Tropic Biosciences is a genome editing company founded in 2016 by Gilad Gershon.

Location:

Key people:

4

Funding Rounds

$7.8m

Money raised

Canopy Biosciences is a company that aims to increase the commercialization of life science reagent tools and services via in-licensing key technologies.

Key people:

1

Funding Rounds

Biotech company developing technologies to improve efficiency and safety of CRISPR-Cas gene editing through anti-CRISPR proteins, also known as Acr proteins

2

Funding Rounds

$5.8m

Money raised

Phytoform Labs is a biotechnology company.

Location:

Key people:

2

Funding Rounds

$695.0m

Money raised

ElevateBio is a company founded by Vikas Sinha, David Hallal and Melissa Carpenter.

1

Funding Rounds

$172.0m

Money raised

Wugen is an off-the-shelf Cell Therapies for Cancer founded by Matthew Cooper, Todd Fehniger, Melissa Berrien-Elliott and John DiPersio.

2

Funding Rounds

$34.0m

Money raised

CureGenetics is a biotechnology company using CRISPR to develop cellular therapies, gene therapies, and molecular diagnostic tools.

Location:

Key people:

3

Funding Rounds

$16.1m

Money raised

Integra Therapeutics is a biotech company engineering the next generation of gene writing tools to cure genetic diseases.

2

Funding Rounds

$260.0m

Money raised

Colossal Biosciences is a biotechnology and genetic engineering company that uses gene editing technology to de-extinct species.

1

Funding Rounds

$70.5m

Money raised

Ensoma, Inc. is an in vivo Gene Therapy founded in 2019.

2

Funding Rounds

$60.0m

Money raised

IASO Biotherapeutics is a biopharmaceutical company focused on the development of cell therapies in the field of oncology.

4

Funding Rounds

$89.0m

Money raised

Latch Bio is a San Francisco-based company founded by Kyle Giffin, Kenny Workman and Alfredo Andere.

Location:

Key people:

3

Funding Rounds

$117.5m

Money raised

Spotlight Therapeutics is an in vivo Gene Editing founded in 2017 by Patrick Hsu, Alexander Marson and Jacob Corn.

1

Funding Rounds

$40.0m

Money raised

Watchmaker Genomics applies enzymology to enable applications for reading, writing and editing DNA.

Location:

Key people:

1

Funding Rounds

$1.6m

Money raised

Cultured Decadence is a Wisconsin-based cellular agriculture company using cell culture and tissue engineering technologies to make lobster meat directly from the animal's cells. The company was acquired by Upside Foods in January 2022.

2

Funding Rounds

$315.0m

Money raised

Prime Medicine is a gene Editing Technology founded in 2019 by David R. Liu.

Key people:

1

Funding Rounds

$14.0m

Money raised

Hui-Gene Therapeutics is a company founded in 2018 by Xuan Yao.

Location:

Key people:

2

Funding Rounds

$530.0m

Money raised

Tessera Therapeutics is a biotechnology company pioneering Gene Writing™ to drive advancements in genome engineering.

Key people:

2

Funding Rounds

$175.0m

Money raised

Metagenomi is a Gene-Edited Microbial Treatments.

2

Funding Rounds

$29.5m

Money raised

ONK Therapeutics is a natural Killer Cell Therapies founded in 2015.

2

Funding Rounds

$35.0m

Money raised

SeQure Dx is a diagnostics company specializing in gene-editing.

Key people:

1

Funding Rounds

$45.0m

Money raised

Proof Diagnostics is harnessing CRISPR technology to unlock powerful molecular diagnostics for all, starting with COVID-19 testing.

1

Funding Rounds

$175.0m

Money raised

Affini-T Therapeutics, Inc is a TCR Cell Therapy.

1

Funding Rounds

$87.0m

Money raised

Clade Therapeutics is a stem Cell Therapies founded by Jim Glasheen, Chad Cowan and Leandro Vetcher.

2

Funding Rounds

$30.0m

Money raised

Avectas is a Non-Viral Cell Manufacturing Technology.

1

Funding Rounds

$55.0m

Money raised

Epic Bio is a biotechnology company developing ultracompact therapies to modulate gene expression in vivo using the smallest known Cas protein, CasMINI.

1

Funding Rounds

$50.0m

Money raised

iECURE is a gene Editing Therapies.

1

Funding Rounds

$80.0m

Money raised

1

Funding Rounds

$4.0m

Money raised

CRISPRQC INC. is a quality Control for CRISPR founded in 2021.

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