69 Best Healthcare Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of Healthcare Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 427 start-ups with an aggregate funding of $10.5b. The average funding per company in this subset is $152.2m.

Last update to the database: Feb 18, 2025. See changelog.

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5

Funding Rounds

$390.0m

Money raised

PathAI is a Boston-based artificial intelligence company developing therapeutics and healthcare products.

10

Funding Rounds

$930.0m

Money raised

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

4

Funding Rounds

$1.8b

Money raised

Grail is a biotechnology company headquartered in Menlo Park, California that was founded as a spinoff of Illumina Inc and initially headed by Jeffrey Huber in 2016, focused on making a medical device that can detect early stage cancer.

3

Funding Rounds

$125.0m

Money raised

Synchron, Inc. is a technology company building implantable neural interface solutions, including endovascular brain-computer interface.

8

Funding Rounds

$71.3m

Money raised

Notable Labs is a company providing personalized drug combination testing service for cancer patients.

9

Funding Rounds

$276.0m

Money raised

A diagnostic DNA testing company using quantified biological data.

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

6

Funding Rounds

$399.8m

Money raised

Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.

Key people:

3

Funding Rounds

$313.0m

Money raised

Flatiron Health is a startup that organizes real-time oncology data to help cancer patients and doctors.

5

Funding Rounds

$375.0m

Money raised

Zocdoc is a company an online medical care appointment booking service.

3

Funding Rounds

$21.5m

Money raised

RoosterBio is a biotechnology company located in Frederick, Maryland, founded by Jon Rowley in 2013 providing standardized stem cell products for R&D, clinical, and commercial use in the regenerative medicine industry.

5

Funding Rounds

$111.8m

Money raised

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

1

Funding Rounds

$24.1m

Money raised

Neos Therapeutics is a pharmaceutical company developing ADHD medications founded in 2008.

6

Funding Rounds

$714.0m

Money raised

An insurance technology offering a platform for companies to manage health insurance policies for their employees.

5

Funding Rounds

$68.7m

Money raised

AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.

Key people:

5

Funding Rounds

$2.3m

Money raised

An app that aggregates social media data to produce a real-time map of sickness.

8

Funding Rounds

$117.5m

Money raised

Locus Biosciences is a biotechnology company developing CRISPR-Cas3-engineered precision antibacterial products.

Key people:

16

Funding Rounds

$328.8m

Money raised

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

6

Funding Rounds

$15.8m

Money raised

Massive Bio is a New York-based company founded by Selin Kurnaz, Dr. Arturo Loaiza-Bonilla and Cagatay M. Culcuoglu, offering precision oncology services to cancer patients, providers, and pharmaceutical companies.

2

Funding Rounds

$13.8m

Money raised

A biopharmaceutical company developing therapeutics to attack cancer stem cells.

3

Funding Rounds

$32.0m

Money raised

miRagen is a clinical stage biopharmaceutical company developing innovative microRNA-targeting therapies to improve human health.

Key people:

1

Funding Rounds

EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.

10

Funding Rounds

$36.3m

Money raised

Chronicled is a blockchain company founded by Ryan Orr, Samantha Radocchia, Maurizio Greco and David Aho.

3

Funding Rounds

$31.2m

Money raised

Deep Lens is an Artificial Intelligence company matching patients with clinical trials.

Industries:

Key people:

3

Funding Rounds

$8.6m

Money raised

Nebula Genomics is a genetics company developing a platform for individuals to get their personal genome sequenced, and then enable them to store and control that information through cryptographic encryption on the blockchain.

Key people:

2

Funding Rounds

$164.5m

Money raised

Develops novel cell and gene therapies with pharmacologic operating systems.

2

Funding Rounds

$6.0m

Money raised

Privy is a company founded in 2011 by Ben Jabbawy.

Key people:

12

Funding Rounds

$2.8m

Money raised

HelixNano is a Cambridge, Massachusetts-based biotechnology and artificial intelligence company founded in 2013 by Hannu Rajaniemi and Nikolai Eroshenko.

8

Funding Rounds

$967.6m

Money raised

Freenome is a San Francisco-based company which uses genetic analysis for early cancer detection and risk assessment.

3

Funding Rounds

$26.2m

Money raised

TRIPP is a digital wellness company that produces a VR meditation app.

2

Funding Rounds

$18.1m

Money raised

A biotechnology company that develops treatments for cancer and hematologic conditions

5

Funding Rounds

$15.6m

Money raised

NextStep is an information technology company providing training and job placement for workers through a mobile application platform.

5

Funding Rounds

$26.8m

Money raised

A biotechnology company developing live attenuated vaccines. It was founded in 2012 and is located in New York.

7

Funding Rounds

$249.0m

Money raised

Eko Health is a digital health and AI technology company developing tools for heart and lung disease detection.

Key people:

3

Funding Rounds

$52.0m

Money raised

3T Biosciences is a biotechnology company developing immunotherapies.

4

Funding Rounds

$30.0m

Money raised

Company manufacturing 3d printed pharmaceuticals based in San Francisco, CA

Key people:

3

Funding Rounds

$5.3m

Money raised

An insurance technology company offering a platform for healthcare organizations to access health insurance data to improve their ability to bring new products and services to market.

7

Funding Rounds

$102.9m

Money raised

Xenex Disinfection Services is a company that provides pulsed xenon ultraviolet-C, room disinfection systems to healthcare facilities

Key people:

1

Funding Rounds

$10.5m

Money raised

SmartPharm Therapeutics is a Cambridge, MA-based gene therapy company applying the next generation of non-viral DNA and RNA technologies to treat serious human diseases.

1

Funding Rounds

$3.0m

Money raised

Youper is an AI-based emotional health assistant company founded in 2016 by Jose Hamilton Vargas, Diego Dotta and Thiago Antonio Marafon.

5

Funding Rounds

$24.1m

Money raised

BetterDoctor, a technology company, delivers provider directory data and has a database that can be accessed through a responsive API.

Key people:

3

Funding Rounds

$152.0m

Money raised

Doctor On Demand is an online service for patients to see their physician on their computer, tablet, or phone.

Key people:

2

Funding Rounds

$2.0m

Money raised

Antera Therapeutics is an allergy prevention development company.

Key people:

5

Funding Rounds

$425.0m

Money raised

Tmunity Therapeutics is a biotechnology company developing t-cell immunotherapies for the treatment of human diseases.

2

Funding Rounds

$24.5m

Money raised

An insurance technology company offering a platform for employee benefits and insurance.

Key people:

4

Funding Rounds

$205.5m

Money raised

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

5

Funding Rounds

$14.5m

Money raised

Aegle Therapeutics Corporation, a regenerative medicine company isolating extracellular vesicles ("EVs") from allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat severe dermatological conditions, including burns and epidermolysis bullosa (“EB”).

Key people:

1

Funding Rounds

$1.0m

Money raised

Choix is a telemedicine clinic providing reproductive and sexual healthcare.

4

Funding Rounds

$28.0m

Money raised

Modern Fertility is a company developing home fertility test for women

1

Funding Rounds

$1.0m

Money raised

Sanguine is a company that has the mission to accelerate medical research by eliminating the barriers to patient participation.

6

Funding Rounds

$144.3m

Money raised

An insurance technology company offering a platform for consumers to purchase and manage their healthcare expenses.

Key people:

3

Funding Rounds

$117.5m

Money raised

A biopharmaceutical company focused on developing treatments for urea cycle disorders and other rare diseases

Key people:

5

Funding Rounds

$81.5m

Money raised

A blockchain platform for exchanging financial information without sharing data. It is located in Marina Del Rey, California and was founded in 2017.

Key people:

9

Funding Rounds

$617.8m

Money raised

Carbon Health is a healthcare company. They primarily serve California and the Reno area.

2

Funding Rounds

$46.7m

Money raised

Whill is a company known for designing, creating, and making personal mobility devices and products.

Industries:

Key people:

6

Funding Rounds

$146.5m

Money raised

A technology company making a air purifier using nanotechnology to destroy pollutants.

Key people:

2

Funding Rounds

$40.0m

Money raised

54Gene is healthcare startup company providing a genetics testing platform in Africa. It also offers genetic reports on health, nutrition, fitness and weight loss, carrier status, personal traits and ancestry.

Key people:

2

Funding Rounds

$16.6m

Money raised

Protein tests company based in Berkeley founded by Akwasi Apori

4

Funding Rounds

$6.4m

Money raised

Nanome is a company developing software for life sciences, materials sciences and nano-engineering with the use of virtual reality and blockchain technology.

3

Funding Rounds

$64.0m

Money raised

Oraya Therapeutics is a biotechnology company developing non-invasive therapies for eye diseases that is headquartered in San Francisco, California and was founded in 2007 by Michael Gertner.

1

Funding Rounds

Leucadia Therapeutics is a company working on Alzheimer's Disease.

5

Funding Rounds

$134.1m

Money raised

Verge Genomics is a company focused on the discovery and development of drugs for the treatment of neurodegenerative diseases with the use of machine learning and computational genomics.

Key people:

1

Funding Rounds

$1.8m

Money raised

An insurance technology company offering a telehealth platform for connecting doctors to employees through their company's health plan.

1

Funding Rounds

$21.0m

Money raised

A company that cultures human mammary cells and produces custom and commercial lab-grown breastmilk. It was founded in 2020 and is located in Durham, North Carolina.

Key people:

1

Funding Rounds

$14.9m

Money raised

Anavasi Diagnostics is a medical technology company focusing on molecular diagnostic testing.

Industries:

Key people:

2

Funding Rounds

$25.2m

Money raised

Eligible is a medical billing company founded in 2011 that aims to make it easier for patients to predict how much their health insurance will pay and how much they will pay out of pocket prior to visiting their doctor.

1

Funding Rounds

$3.9m

Money raised

Tempo Therapeutics is an interventional biomaterials for regenerative medicine company founded by Westbrook Weaver.

Key people:

1

Funding Rounds

$1.7m

Money raised

Celdara Medical is a biotechnology company helping turn academic innovations into medical products.

Key people:

9

Funding Rounds

$56.6m

Money raised

A company based in Farmington, Connecticut, that develops skin disease treatments using microbiome science and technology.

Key people:

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