69 Best Digital Therapeutics Startups to Watch in 2025

The Definitive Seedtable Ranking of Digital Therapeutics Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 103 start-ups with an aggregate funding of $10.9b. The average funding per company in this subset is $157.8m.

Last update to the database: Feb 18, 2025. See changelog.

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Hinge Health logo

Hinge Health

The World's First Digital Clinic for Back and Joint Pain

11

Funding Rounds

$4.1b

Money raised

Livongo Health logo

Livongo Health

Livongo Health is an IT healthcare company developing and providing a digital platform health monitoring solution.

6

Funding Rounds

$235.0m

Money raised

nOCD (health information technology company) logo

nOCD (health information technology company)

NOCD provides online therapy for obsessive-compulsive disorder (OCD).

7

Funding Rounds

$99.0m

Money raised

Legacy (company) logo

Legacy (company)

A digital fertility clinic offering semen analysis, sperm improvement, and sperm cryostorage services. Founded at Harvard in 2018, the company has raised $20M from investors like Y Combinator, Bain Capital Ventures, FirstMark Capital, and celebrities like Justin Bieber.

4

Funding Rounds

$6.5m

Money raised

TRIPP logo

TRIPP

TRIPP is a digital wellness company that produces a VR meditation app.

3

Funding Rounds

$26.2m

Money raised

HyperScience logo

HyperScience

HyperScience is a AI enabled company for office work company founded in 2014 by Peter Brodsky, Krasimir Marinov and Vladimir Tzankov.

6

Funding Rounds

$238.9m

Money raised

Flow Neuroscience logo

Flow Neuroscience

Flow Neuroscience is a Malmo, Sweden-based medical technology company developing treatments for mental health issues. The company offers a medication-free depression treatment that combines a brain stimulation wearable and an app-based therapy program.

2

Funding Rounds

$2.6m

Money raised

Aetion logo

Aetion

Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.

6

Funding Rounds

$230.6m

Money raised

SWORD Health logo

SWORD Health

SWORD Health is a digital therapy provider for pain.

12

Funding Rounds

$576.4m

Money raised

InteraXon logo

InteraXon

InteraXon develops and produces brain-sensing technology such as the Muse headband, an EEG device that interprets mental activity and aims to help with meditation and promote calmness.

4

Funding Rounds

$28.8m

Money raised

Biofourmis logo

Biofourmis

Biofourmis is a global health IT start-up in Massachusetts that focuses on personalized care and therapies using digital therapeutics.

7

Funding Rounds

$443.5m

Money raised

Buoy Health logo

Buoy Health

Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.

3

Funding Rounds

$59.2m

Money raised

Sentio Solutions logo

Sentio Solutions

A healthcare technology company that develops biomarkers and digital therapeutics. It was founded in 2015 and is located in San Francisco, California.

3

Funding Rounds

$15.2m

Money raised

Omada Health logo

Omada Health

A digital behavioral medicine company dedicated to inspiring and empoTheyring people everywhere to live free of chronic illiness.

9

Funding Rounds

$400.5m

Money raised

Alex Therapeutics logo

Alex Therapeutics

AI-powered CBT therapeutic platform.

4

Funding Rounds

$5.1m

Money raised

Limbix logo

Limbix

Palo Alto, California-based Limbix is not your average virtual reality startup: It makes a software that therapists use in what's called "exposure therapy," simulating stressful or trauma-inducing situations for patients to help them overcome their fears.

2

Funding Rounds

$24.0m

Money raised

Thirty Madison logo

Thirty Madison

A full-service healthcare company in New York that focuses on providing medications.

4

Funding Rounds

$217.5m

Money raised

Noom logo

Noom

A fitness company offering a mobile health coaching service.

11

Funding Rounds

$645.7m

Money raised

Mindset Health logo

Mindset Health

Mindset Health aims to replace drugs with app-based hypnotherapy. They help people improve issues like irritable bowel syndrome, anxiety & depression with app-delivered hypnotherapy, produced by world-class doctors.

1

Funding Rounds

$1.1m

Money raised

Maven logo

Maven

Maven Clinic is a virtual clinic dedicated to women and family health.

7

Funding Rounds

$195.1m

Money raised

Theranica logo

Theranica

Theranica is a Netanya-based biomedical technology company focused on developing electronic devices and wireless communication technology.

3

Funding Rounds

$86.0m

Money raised

Meru Health logo

Meru Health

Meru Health provides a digital program to treat depression and burnout. It participated in the S18 cohort of Y Combinator.

4

Funding Rounds

$68.0m

Money raised

Big Health logo

Big Health

Health technology startup that creates personalized behavioral medicine programs

3

Funding Rounds

$126.0m

Money raised

Joint Academy logo

Joint Academy

Joint Academy is a Swedish healthcare company providing a digital platform for the treatment of osteoarthritis.

8

Funding Rounds

$57.2m

Money raised

Voluntis logo

Voluntis

Voluntis is a company that is at the forefront of the medical and digital revolutions, the company is a pioneer in digital therapeutics.

2

Funding Rounds

$23.4m

Money raised

Vivante Health logo

Vivante Health

Vivante Health is a digital health company.

4

Funding Rounds

$35.2m

Money raised

Dopavision logo

Dopavision

Dopavision is a therapeutic company developing a digital therapeutic for myopia.

3

Funding Rounds

$29.5m

Money raised

Hello Heart logo

Hello Heart

Hello Heart is a company founded in 2013 by Ziv Meltzer.

5

Funding Rounds

$151.0m

Money raised

Intellect (Company) logo

Intellect (Company)

Intellect is a developer of business applications, workflow management and QMS software to assist with quality control, regulator compliance, operations, process improvement with departments, services, organizations and through enterprises.

2

Funding Rounds

$24.0m

Money raised

Woebot Health logo

Woebot Health

Woebot Labs is a San Francisco-based company offering an AI-powered mental healthcare platform and chatbot.

3

Funding Rounds

$107.5m

Money raised

Orexo logo

Orexo

Orexo is a pharmaceutical company developing and commercializing drugs founded in 1995 by Anders Pettersson, Christer Nyström and Thomas Lundqvist.

2

Funding Rounds

$72.9m

Money raised

Mindstrong Health logo

Mindstrong Health

Mindstrong Health is a neuroscience precision therapy company founded in 2014 by Paul Dagum.

4

Funding Rounds

$160.0m

Money raised

Ieso Digital Health logo

Ieso Digital Health

Ieso Digital Health is a Cambridge, Cambridgeshire-based digital health company offering internet enabled evidence-based psychological therapies.

1

Funding Rounds

$24.0m

Money raised

MindSciences logo

MindSciences

MindSciences is a company founded in 2014 by Judson Brewer.

1

Funding Rounds

$2.1m

Money raised

MetaMe Health logo

MetaMe Health

MetaMe Health is a telemedicine and company founded in 2015 and headquartered in Chicago, Illinois offering a 6-session hypnosis treatment for Irritable Bowel Syndrome (IBS).

1

Funding Rounds

$3.8m

Money raised

Virta Health logo

Virta Health

Virta is the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.

6

Funding Rounds

$410.0m

Money raised

Quit Genius logo

Quit Genius

The #1 digital clinic for tobacco, vaping, alcohol and opioid addictions.

2

Funding Rounds

$75.0m

Money raised

SilverCloud Health logo

SilverCloud Health

SilverCloud Health is a Dublin-based company offering an online health and wellness platform enabling healthcare organisations and professionals to offer a broad range of engaging interactive healthcare products.

3

Funding Rounds

$26.0m

Money raised

Wellthy Therapeutics logo

Wellthy Therapeutics

Wellthy Therapeutics is an artificial Intelligence company founded in 2015 by Aradh Pillai, Abhishek Shah, Maaz Shaikh and Prayat Shah.

4

Funding Rounds

$8.5m

Money raised

Sidekickhealth logo

Sidekickhealth

Sidekick Health has built a gamified digital care platform that targets chronic and lifestyle disease management.

1

Funding Rounds

$20.0m

Money raised

Numan logo

Numan

Numan is a startup which aims to tackle your tackle problem erectile dysfunction.

5

Funding Rounds

$166.1m

Money raised

AppliedVR logo

AppliedVR

AppliedVR is a company founded in 2015 by Matthew Stoudt.

2

Funding Rounds

$65.0m

Money raised

Cerebral logo

Cerebral

Cerebral offers online medication prescription, care counseling and treatment for anxiety, depression and insomnia. Includes doctor's visits and medication delivery.

3

Funding Rounds

$462.0m

Money raised

Syrona Health logo

Syrona Health

Syrona Women is a company with a platform for digital healthcare directed at women that can track and screen for medical situations such as endrometriosis, fertility, PCOS, etc.

1

Funding Rounds

$500.0k

Money raised

Learning to Sleep logo

Learning to Sleep

Learning To Sleep offers a range of clinically-proven sleep improvement programs.

2

Funding Rounds

$2.5m

Money raised

Click Therapeutics, Inc. logo

Click Therapeutics, Inc.

Click Therapeutics delivers safe and effective digital treatments to patients in need.

3

Funding Rounds

$34.0m

Money raised

Second Nature logo

Second Nature

Second Nature is a smartphone application that coaches and motivates diabetes patients to live a healthier lifestyle. OurPath is a lifestyle improvement programme, proven to help people reduce the risk and complications of type 2 diabetes.

1

Funding Rounds

$10.0m

Money raised

YourCoach Health logo

YourCoach Health

YourCoach Health is a company founded in 2020 by Daniel Kogan, Eugene Borukhovich and Marina Borukhovich.

1

Funding Rounds

$1.3m

Money raised

Mahana Therapeutics logo

Mahana Therapeutics

Mahana Therapeutics is a San Francisco-based digital therapeutics company developing treatments and software aimed at helping those with inflammatory bowel diseases.

2

Funding Rounds

$73.0m

Money raised

Kaia health logo

Kaia health

Kaia health is an artificial Intelligence company founded in 2016 by Konstantin Mehl.

4

Funding Rounds

$119.0m

Money raised

Akili Interactive logo

Akili Interactive

Akili Interactive is a company founded in 2011.

4

Funding Rounds

$239.9m

Money raised

CureApp logo

CureApp

CureApp is a company that is recreating treatment with software.

5

Funding Rounds

$48.0m

Money raised

cognoa logo

cognoa

Silicon Valley-based Cognoa, founded in 2014, offers a tool to evaluate childhood development and highlight development delays and autism. The development evaluation, supported by AI and created in partnership with Harvard and Stanford Medical Schools, covers children aged 1-8. Clinical studies show that the diagnostic tool is significantly more accurate than standard practice screeners of the same age. The company also provides clinical advice, improves childhood development and, when necessary, recommends clinical and medical support. Parent testimonials highlight the range of available activities to help needy children and parents facing similar problems.

1

Funding Rounds

$11.6m

Money raised

Naluri logo

Naluri

Naluri is a Malaysia-based company founded in 2017 by Azran Osman Rani, Jeremy Ting and Hariyati Abdul Majid.

3

Funding Rounds

$13.5m

Money raised

Ophelia logo

Ophelia

Ophelia is a company founded in 2019 by Mattan Griffel.

3

Funding Rounds

$67.7m

Money raised

VisionHealth GmbH logo

VisionHealth GmbH

VisionHealth supports patients with chronic lung diseases who are dependent on their inhaler.

4

Funding Rounds

$5.3m

Money raised

BrainQ logo

BrainQ

BrainQ develops Artificial Intelligence-powered technologies to treat neuro-disorders in innovative ways.

2

Funding Rounds

$48.8m

Money raised

Blueheart logo

Blueheart

Sex therapy app company based in Rickmansworth, England.

2

Funding Rounds

$2.6m

Money raised

Boulder Care logo

Boulder Care

Boulder harnesses mobile technology to expand access to treatment for opioid use

2

Funding Rounds

$39.7m

Money raised

Propeller Health logo

Propeller Health

Propeller Health is a Madison, Wisconsin-based company offering sensors, mobile apps, analytics and services to support respiratory health management.

3

Funding Rounds

$48.5m

Money raised

Monument logo

Monument

Monument is an online alcohol addiction treatment platform.

2

Funding Rounds

$17.8m

Money raised

PeerWell logo

PeerWell

PeerWell is a San Francisco-based company founded in 2015 by Manish Shah, Navin Gupta and Evan Minamoto.

3

Funding Rounds

$15.1m

Money raised

Liva Healthcare logo

Liva Healthcare

Liva's digital coaching platform provides scalable lifestyle change, disease management & patient engagement for NHS England, AXA PPP & more

4

Funding Rounds

$78.2m

Money raised

Workit Health logo

Workit Health

Provider of an online addiction recovery program intended to deliver improved addiction care through technology, experience, and design.

4

Funding Rounds

$131.1m

Money raised

DiogenX logo

DiogenX

DiogenX is a regenerative diabetes treatment founded in 2019 by Jean-Pascal Tranié, Benjamin Charles and Patrick Collombat.

2

Funding Rounds

$35.1m

Money raised

Alpha Medical logo

Alpha Medical

Alpha Medical is a Palo Alto, California-based company.

1

Funding Rounds

$24.0m

Money raised

StoryUP XR  logo

StoryUP XR

StoryUP creates data-driven VR escapes for areas of acute stress. Using BCI (brain computer interface), we also enable the user to control some experiences with their own brainwaves.

1

Funding Rounds

$1.3m

Money raised

Tilak Healthcare logo

Tilak Healthcare

Tilak Healthcare is a company founded in 2016.

1

Funding Rounds

$2.7m

Money raised

Cara Care logo

Cara Care

Empowers every individual with digestive issues to enjoy a healthier and happier life.

3

Funding Rounds

$21.0m

Money raised