69 Best Cardiology Startups to Watch in 2025

The Definitive Seedtable Ranking of Cardiology Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 79 start-ups with an aggregate funding of $6.2b. The average funding per company in this subset is $90.3m.

Last update to the database: Feb 18, 2025. See changelog.

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3

Funding Rounds

$145.0m

Money raised

Cala Health offers bioelectronic medicines, medical devices, and neurotherapeutics for managing chronic health conditions.

Key people:

5

Funding Rounds

$48.1m

Money raised

Spire is a company developing tags that provide health tracking including respiration, sleep, stress, activity, and pulse rate.

Location:

Key people:

3

Funding Rounds

$32.0m

Money raised

miRagen is a clinical stage biopharmaceutical company developing innovative microRNA-targeting therapies to improve human health.

Key people:

2

Funding Rounds

$13.8m

Money raised

A molecular diagnostics company developing novel blood-based early detection and disease monitoring tests based on analyzing circulating cell-free messenger RNA (cf-mRNA) in blood samples to monitor organ function.

7

Funding Rounds

$249.0m

Money raised

Eko Health is a digital health and AI technology company developing tools for heart and lung disease detection.

Key people:

9

Funding Rounds

$807.7m

Money raised

HeartFlow is a company developing non-invasive cardiovascular disease detection technology.

Key people:

1

Funding Rounds

$5.5m

Money raised

A biotechnology company founded in 2013 that develops technology to treat heart disease using pluripotent stem cells. Disease in a dish and clinical trial in a dish platforms are used to develop cardiovascular drugs and perform cardio-toxicity safety testing for non-cardiovascular drugs.

2

Funding Rounds

$1.0b

Money raised

RNA-guided regulatory genome targeting therapeutics developer for chronic diseases.

Location:

Key people:

3

Funding Rounds

$105.0m

Money raised

A biopharmaceutical company developing therapeutics for treating age-related diseases.

6

Funding Rounds

$117.7m

Money raised

AliveCor is a San Francisco-based company developing AI-based ECG technologies.

3

Funding Rounds

$26.9m

Money raised

Moving Analytics is developing a virtual care management software for cardiac rehab.

6

Funding Rounds

$62.1m

Money raised

Crown bioscience is a company that is focused on research, drug discovery and development for the treatment of cancer and diabetes.

5

Funding Rounds

$23.2m

Money raised

By applying the latest research in Artificial intelligence, Cardiologs provides a web solution to streamline this process at large scale, enabling the highest diagnostic yield, for the least physician effort.

5

Funding Rounds

$151.0m

Money raised

Hello Heart is a company founded in 2013 by Ziv Meltzer.

Key people:

4

Funding Rounds

$144.0m

Money raised

A cardiovascular genomic diagnostics company that provides clinicians information to improve patient care

4

Funding Rounds

$74.0m

Money raised

A company that develops tools and techniques to treat heart failure and related conditions

12

Funding Rounds

$276.6m

Money raised

A company developing hemodynamic monitoring solutions to detect heart failure

Location:

Key people:

1

Funding Rounds

$23.1m

Money raised

NeuroTronik is a company that develops neurostimulation therapeutic devices which are designed to treat acute heart failure syndrome.

6

Funding Rounds

$249.0m

Money raised

Rockley Photonoics develops silicon photonics for applications that include including data center connectivity, autonomous vehicles and medical sensing

Key people:

3

Funding Rounds

$54.5m

Money raised

Implicity developed a universal remote monitoring platform for cardiac patients with connected pacemakers and implantable defibrillators.

Location:

Key people:

3

Funding Rounds

$94.0m

Money raised

Volta Medical is an artificial intelligence to revolutionize interventional cardiac electrophysiology founded in 2016 by Théophile Mohr Durde, Julien Seitz and Jérome Kalifa.

Key people:

2

Funding Rounds

$28.2m

Money raised

Heartbeat is an experience created to screen, diagnose, track and manage cardiovascular risk and disease to keep you at your healthiest.

3

Funding Rounds

$66.0m

Money raised

Ultromics is an artificial Intelligence company founded in 2017 by Paul Leeson.

Location:

Key people:

6

Funding Rounds

$93.5m

Money raised

VoxelCloud provides automated medical image analysis services and diagnosis assistance based on AI and cloud computing technologies.

15

Funding Rounds

$114.9m

Money raised

BioVentrix is a San Ramon, California-based medical device company that focuses on improving and expanding the treatment available for congestive heart failure (CHF) caused by ischemic cardiomyopathy, through the development of less invasive, catheter-based approaches.

2

Funding Rounds

$22.3m

Money raised

Products to detect heart problems at an early stage to prevent heart diseases.

6

Funding Rounds

$80.7m

Money raised

InfoBionic is an arrhythmia detection and monitoring founded in 2011 by Nancy Briefs, Jeremy Ruskin and Ravi Kuppuraj.

2

Funding Rounds

$58.5m

Money raised

Caption Health is a company founded in 2013.

2

Funding Rounds

$91.7m

Money raised

Cardior Pharmaceuticals discovers and develops medicines and therapeutics for the treatment and prevention of heart disease.

Location:

Key people:

1

Funding Rounds

GenesisCare is a company founded in 2001.

1

Funding Rounds

$10.0m

Money raised

Boston Heart Diagnostics is a Framingham, Massachusetts-based healthcare company offering diagnostics and health management tools for cardiovascular disease.

Key people:

3

Funding Rounds

$80.5m

Money raised

Avinger is a Redwood City, California-based medical device company that designs, manufactures, and sells image-guided, catheter-based systems for the treatment of patients with peripheral artery disease (PAD).

2

Funding Rounds

$8.2m

Money raised

CardiaTec is an AI-powered cardiovascular drug discovery platform founded in 2021 by Thelma Zablocki, Raphael Peralta and Namshik Han.

Key people:

1

Funding Rounds

$196.0m

Money raised

NewAmsterdam Pharma is a company focusing on the treatment of cardio-metabolic diseases.

2

Funding Rounds

$72.1m

Money raised

InCarda Therapeutics is a company developing therapies for cardiovascular diseases founded in 2009 by Carlos A. Schuler.

2

Funding Rounds

$235.0m

Money raised

Cleerly is a digital healthcare company that offers heart disease diagnosis solutions.

1

Funding Rounds

$3.5m

Money raised

Cardiomatics uses artificial intelligence for electrocardiogram (ECG) reading automation technology.

1

Funding Rounds

$10.0m

Money raised

Tara Biosystems is a heart on-a-chip founded in 2014 by Kacey Ronaldson.

1

Funding Rounds

$10.3m

Money raised

Acarix is a Malmö-based company manufacturing diagnostic systems for coronary artery disease.

2

Funding Rounds

$58.9m

Money raised

XyloCor Therapeutics is focused on improving the lives of people with cardiovascular disease through our commitment to advancing the science of gene therapy.

4

Funding Rounds

$43.4m

Money raised

Metcela is a cell Therapy founded in 2016.

1

Funding Rounds

A technology company offering research and development services focused on cardiovascular disease.

2

Funding Rounds

$9.7m

Money raised

BioStable Science and Engineering is an Austin, Texas-based cardiovascular device company.

2

Funding Rounds

$167.0m

Money raised

Rivus Pharmaceuticals is dedicated to improving cardio-metabolic health by developing controlled metabolic accelerators (CMAs) that address the underlying metabolic risk factors for cardiovascular mortality and morbidity.

2

Funding Rounds

$44.0m

Money raised

Heart Health Intelligence creates heart data collecting toilet seat, reducing the cost of heart failure through seamless in-home monitoring.

1

Funding Rounds

$118.0m

Money raised

Mineralys Therapeutics is a small Molecules founded in 2020 by BT Slingsby.

2

Funding Rounds

$29.0m

Money raised

Automated External Defibrillator

3

Funding Rounds

$33.6m

Money raised

Amyl Therapeutics unique technology offers a curative solution for all forms of amyloid mediated diseases

Location:

Key people:

1

Funding Rounds

$16.0m

Money raised

Shift Bioscience is an AI-driven cell simulation platform founded in 2017 by Daniel Ives.

Key people:

2

Funding Rounds

$75.0m

Money raised

Orchestra BioMed Inc is a medical devices founded in 2017 by David P. Hochman.

Key people:

1

Funding Rounds

$50.0m

Money raised

Vero Biotech is a nitric Oxide Generation & Delivery.

Location:

Key people:

1

Funding Rounds

$70.0m

Money raised

V-Wave is an interatrial shunt for heart failure.

1

Funding Rounds

$20.0m

Money raised

Sensible Medical Innovations is a lung Fluid Measurement for Heart Failure Patients founded in 2007 by Amir Ronen, Amir Saroka, Dan Rappaport, Nadav Mizrahi and Shlomi Bergida.

Location:

Key people:

3

Funding Rounds

$34.9m

Money raised

Small Molecules based on Omega-3 Fatty acid metabolites

1

Funding Rounds

$35.5m

Money raised

Bardy Diagnostics, Inc. is a Charlotte, North Carolina-based diagnostic tools company founded in 1985.

1

Funding Rounds

$25.0m

Money raised

RapidAI offers a cerebrovascular imaging platform for diagnostic and treatment decisions for stroke patients.

1

Funding Rounds

$3.0m

Money raised

Bloomer Tech is a Cambridge, Massachusetts-based company.

2

Funding Rounds

$3.0m

Money raised

Vixiar Medical develops non-invasive, cost-effective devices and systems for monitoring cardiopulmonary diseases.

2

Funding Rounds

$138.1m

Money raised

Cardiovascular treatments

1

Funding Rounds

$8.0m

Money raised

Elucid Bioimaging Inc. is an arterial Analysis Software founded in 2009.

7

Funding Rounds

$168.0m

Money raised

4C Medical Technologies, Inc. is a company founded in 2015.

1

Funding Rounds

$17.8m

Money raised

Ancora Heart is a cardiac procedures for Mitral Valve Regurgitation founded in 2015.

3

Funding Rounds

$19.0m

Money raised

Magenta Medical has developed a temporary venous catheter-based therapy for hospital-admitted patients with Acute Decompensated Heart Failure (ADHF).

Location:

1

Funding Rounds

$20.0m

Money raised

A medical device company developing bioresorbable scaffolds for vascular and nonvascular applications

4

Funding Rounds

$19.7m

Money raised

Saranas is a blood vessel access device founded in 2013.

1

Funding Rounds

$12.5m

Money raised

Vector is a cardiac digital health provider that makes it simple for care teams to capture, manage, analyze, and act on remote cardiac data.

2

Funding Rounds

$63.0m

Money raised

Heartseed is a biotech company developing iPSC-derived highly purified ventricular cardiomyocytes for heart failure

4

Funding Rounds

$9.6m

Money raised

AUM Cardiovascular is a Northfield, Minnesota-based medical diagnostics company developing medical devices for diagnostics.

1

Funding Rounds

$17.5m

Money raised

Angel Medical Systems is a heart attack detection founded in 2001.

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