7 Best Spider Silk Startups to Watch in 2025

The Definitive Seedtable Ranking of Spider Silk Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 7 start-ups with an aggregate funding of $1.8b. The average funding per company in this subset is $256.6m.

Last update to the database: Feb 18, 2025. See changelog.

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Bolt Threads logo

Bolt Threads

Bolt Threads is a biotechnology company that makes high performance fabrics and materials using biology.

8

Funding Rounds

$406.4m

Money raised

Spiber, Inc. logo

Spiber, Inc.

Spiber, Inc is a private biomaterials company using industrial biotechnology to develop silk.

13

Funding Rounds

$1.1b

Money raised

AMSilk logo

AMSilk

AMSilk is a Munich-based synthetic biology company that produces fibers made from the same protein as spider silk.

6

Funding Rounds

$129.3m

Money raised

Vaxess Technologies logo

Vaxess Technologies

A medical company in Massachusetts focusing on lowering the cost of vaccine distribution.

14

Funding Rounds

$87.2m

Money raised

Kraig Biocraft Laboratories logo

Kraig Biocraft Laboratories

A biotechnology company developing and commercializing spider silk for textiles and performance polymers. Kraig Biocraft Laboratories uses genetic engineering to produce recombinant spider silk based fibers on an industrial scale.

4

Funding Rounds

$14.0m

Money raised

EV Biotech logo

EV Biotech

EV Biotech is a microbial cell factory (MCF) strain development company.

1

Funding Rounds

$4.7m

Money raised

Xampla logo

Xampla

Xampla is a Cambridge, Cambridgeshire-based company founded in 2018 by Tuomas Knowles.

2

Funding Rounds

$11.0m

Money raised