69 Best Startups in Illinois to Watch in 2025

The Definitive Seedtable Ranking of Startups in Illinois

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 1,132 start-ups with an aggregate funding of $16.8b. The average funding per company in this subset is $243.2m.

Last update to the database: Feb 18, 2025. See changelog.

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7

Funding Rounds

$875.5m

Money raised

C3 AI is an enterprise artificial intelligence software company providing a family of integrated products for accelerating digital transformation.

4

Funding Rounds

$165.0m

Money raised

Elastic is a software company that creates products for searching for information on the Internet. It was founded in 2012 and is headquartered in San Francisco and Amsterdam.

9

Funding Rounds

$1.1b

Money raised

Circle is a peer-to-peer payments technology company that is headquartered in Boston, Massachusetts and was founded in 2013 by Jeremy Allaire and Sean Neville.

10

Funding Rounds

$930.0m

Money raised

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

5

Funding Rounds

$60.2m

Money raised

U.S-based 3D media technology company providing worldwide end-to-end virtual media solutions.

7

Funding Rounds

$638.8m

Money raised

TradingView is a platform which provides instruments for publication and the viewing of trading ideas.

7

Funding Rounds

$99.0m

Money raised

NOCD provides online therapy for obsessive-compulsive disorder (OCD).

6

Funding Rounds

$80.5m

Money raised

Hologram is a company with a platform for building Internet of Things type products

4

Funding Rounds

$24.0m

Money raised

ASOCS is a Rosh HaAyin-based cloud management and software company developing virtualized network solutions and founded in 2003 by Gilad Garon.

2

Funding Rounds

$110.3m

Money raised

Big Time is a multiplayer action RPG that makes collectable NFTs accessible to everyone.

9

Funding Rounds

$852.6m

Money raised

Fetch Rewards is a mobile shopping platform for earning points and rewards on purchases.

3

Funding Rounds

$58.0m

Money raised

Arturo.ai is a Chicago-based insurance technology and artificial intelligence company.

9

Funding Rounds

$407.9m

Money raised

Kin Insurance is an insurance technology company offering home insurance founded in 2016.

4

Funding Rounds

$167.0m

Money raised

League is a digital health benefits provider.

5

Funding Rounds

$9.7m

Money raised

Avail is a Chicago-based company developing free landlord software to help with rental property management.

6

Funding Rounds

$265.4m

Money raised

A New Zealand industrial biotechnology company developing a gas fermentation platform for converting concentrated industrial emissions into valuable chemicals.

6

Funding Rounds

$1.8b

Money raised

Signature Bank is a New York City-based company founded in 2023.

Industries:

Location:

Key people:

4

Funding Rounds

$73.0m

Money raised

Wickr is a telecommunications and security company that builds secure communication tools, such as a messaging application. It was founded in 2012 and is located in San Francisco, California.

3

Funding Rounds

$113.0m

Money raised

Natural Fiber Welding is a Peoria, Illinois-based company developing a scalable fabrication platform that can offset the global dependence on petroleum-based, human-made materials.

2

Funding Rounds

$8.0m

Money raised

Loop Crypto is an auto payment platform for on-chain crypto payments.

Industries:

8

Funding Rounds

$1.3b

Money raised

ShipBob is a company offering logistics services to small- to mid-sized businesses.

10

Funding Rounds

$794.5m

Money raised

Addepar is a leading provider of technology for the wealth management industry. The company's performance reporting and analytics platform aggregates portfolio, market, and client data all in one place. It provides asset owners and advisors a clearer financial picture at every level, allowing them to make more informed and timely investment decisions. Addepar works with leading financial advisors, family offices, and large financial institutions that manage over $1.3 trillion of assets on the company's platform. In 2018, Addepar was named as a Forbes Fintech 50 and received Morgan Stanley's Fintech Award for making significant impact to the firm's mission of continuous innovation. Addepar is headquartered in Silicon Valley and has offices in New York, New York City, Chicago, Illinois, and Salt Lake City.

11

Funding Rounds

$908.0m

Money raised

Project44 is a visibility platform for shippers and third-party logistics firms tracking the supply chain.

3

Funding Rounds

$36.0m

Money raised

Fingerprint is a developer of an application programming interface designed for fraud detection on the modern web.

4

Funding Rounds

$73.0m

Money raised

An insurance technology company offering a platform for insurance claims.

7

Funding Rounds

$169.9m

Money raised

Zero Hash is a financial services company specializing in digital assets-as-a-service technology.

8

Funding Rounds

$851.0m

Money raised

Nature's Fynd is a biotechnology company growing edible proteins founded in 2012.

3

Funding Rounds

$50.0m

Money raised

Anodot is a software development company that has created a business monitoring platform.

2

Funding Rounds

$11.5m

Money raised

An artificial intelligence company with a focus on developing solutions for the healthcare industry. It was founded in 2017 and is located in Tel Aviv, Israel.

6

Funding Rounds

$133.4m

Money raised

Common is a NYC-based coliving company founded by Brad Hargreaves founded in 2015 by Brad Hargreaves.

4

Funding Rounds

$8.6m

Money raised

Popular Pays is company providing a platform connecting brands with creators to produce custom content and generate awareness.

1

Funding Rounds

$2.5m

Money raised

LotLinx is a marketing technology suite used in the American and Canadian automotive industry. It is an automotive VIN-specific digital marketing suite.

2

Funding Rounds

$37.0m

Money raised

Fly.io is a Chicago-based platform for deploying full stack application servers and databases close to users.

6

Funding Rounds

$67.8m

Money raised

Fast Radius is a Chicago, IL-based Mechanical and Industrial Engineering company.

1

Funding Rounds

$4.5m

Money raised

Octopai is a centralized, cross-platform metadata management automation solution.

17

Funding Rounds

$28.5m

Money raised

MicroLink devices is a Niles, Illinois-based semiconductor manufacturing company

3

Funding Rounds

$7.1m

Money raised

EarlyBird is a platform for parents looking to invest for their children.

5

Funding Rounds

$101.3m

Money raised

Cleo is a fintech company providing an application for personal finance management.

2

Funding Rounds

$12.0m

Money raised

Wellspring Worldwide is an innovation and technology commercialization program that offers technology scouting, corporate venturing, licensing and intellectual property software for corporations and universities.

3

Funding Rounds

$359.0m

Money raised

Avant is a company operating an online platform providing users access to personal loans. It utilizes big data and machine learning algorithms.

2

Funding Rounds

$24.7m

Money raised

Bright Security (previously NeuraLegion) is a San Rafael, California-based company offering developer-centric dynamic application security testing (DAST) software.

10

Funding Rounds

$1.3b

Money raised

Rent the Runway is a New York City-based company founded in 2009 by Jennifer Hyman.

3

Funding Rounds

$30.0m

Money raised

Instana is a SaaS-based application performance management (APM) platform based in Chicago, Illinois and in the Ohligs borough of Solingen, Germany.

6

Funding Rounds

$6.8m

Money raised

Venzee is a software development company based in Vancouver, Canada. The company offers a cloud-based AI platform for online retailers and vendors.

1

Funding Rounds

$2.5m

Money raised

BiomeSense, Inc. is a biotechnology company developing microbiome technologies for the collection, storage, and analysis of gut microbiome profiles.

4

Funding Rounds

$41.0m

Money raised

Redefine Meat is a food technology company that is making a 3D printer capable of printing plant-based alternative meat products.

1

Funding Rounds

$4.3m

Money raised

CareSkore is a healthcare technology company that provides personalized population health management.

3

Funding Rounds

$36.5m

Money raised

Covenant Surgical Partners is a company that operates ambulatory surgery centers founded in 2008.

4

Funding Rounds

$325.9m

Money raised

Clearcover is a smarter car insurance choice. We deliver the right coverage, when it matters, so you can pay less. Clearcover saves you money by applying advanced technology and only talking to you about insurance in moments that matter - like when you're buying a car, shopping for better insurance rates or managing your finances. With Clearcover, you get the same great coverage as Big Insurance, for up to 40% less per month. Follow along with our progress on Medium: https://medium.com/@ClearcoverInc or on Twitter @Clearcover

1

Funding Rounds

$2.1m

Money raised

Elixir is a company that has developed a protocol for decentralized finance.

3

Funding Rounds

$42.5m

Money raised

RightScale is a Santa Barbara, California-based company founded in 2007 by Jonathan Siegel.

3

Funding Rounds

$455.0m

Money raised

A developer of primary care clinics. VillageMD provides support services to physicians and to patients outside the office visit with aim of better clinical outcomes and enhanced patient experience.

2

Funding Rounds

$75.0m

Money raised

Duda is a responsive website builder for digital marketing agencies, hosting companies, and online directories.

3

Funding Rounds

$3.4m

Money raised

FGC Plasma Solutions is an plasma-assisted combustion technology company founded in 2013 by Felipe Gomez del Campo and Drew Weibel

1

Funding Rounds

$15.0m

Money raised

Seed CX is a cryptocurrency company founded in 2017 by Brian Liston.

4

Funding Rounds

$4.9m

Money raised

Draftbit is a company that gives the option to build a cross-platform, native iOS and Android app.

5

Funding Rounds

$343.0m

Money raised

Uptake is a SaaS company that works with industrial companies to analyze and predict equipment performance.

3

Funding Rounds

$7.5m

Money raised

Next Big Sound provides a dashboard, charts, and reports to monitor popularity, activity, and metrics for musicians, albums, authors and books across social media, sales and events.

5

Funding Rounds

$410.8m

Money raised

Copado is a provider of a DevOps platform for Salesforce users.

Location:

1

Funding Rounds

$2.5m

Money raised

GFX Labs is a technology company with a focus on developing decentralized finance products.

2

Funding Rounds

$173.0k

Money raised

XEME Biopharma is a biotechnology company developing therapeutic cancer vaccines and cancer immunotherapy products.

3

Funding Rounds

$360.0m

Money raised

ActiveCampaign provides a platform with email marketing, marketing automation, and CRM tools for small-to-mid-sized businesses.

3

Funding Rounds

$770.0k

Money raised

Peeranha is a question and answer (Q & A) website that rewards users with cryptocurrency.

4

Funding Rounds

$64.0m

Money raised

A company offering a compliance platform for marketing cannabis products.

1

Funding Rounds

$10.0m

Money raised

BlueCart is an online ordering platform that connects wholesale suppliers and buyers in the hospitality industry.

5

Funding Rounds

$257.0m

Money raised

Coralogix is a company founded in 2014 by Lior Tal, Ariel Assaraf, Lior Redlus and Guy Kroupp.

4

Funding Rounds

$3.1m

Money raised

A technology company providing a commercial real estate asset management platform.

1

Funding Rounds

$12.0m

Money raised

MIGAL Research Institute is a company that provides applied research that is specialized in the fields of biotechnology, environmental and agricultural sciences

Industries:

3

Funding Rounds

$72.0m

Money raised

DataGen Technologies is a data company.

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