69 Best Startups in Madison Wisconsin to Watch in 2025

The Definitive Seedtable Ranking of Startups in Madison Wisconsin

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 96 start-ups with an aggregate funding of $2.5b. The average funding per company in this subset is $36.2m.

Last update to the database: Feb 18, 2025. See changelog.

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9

Funding Rounds

$852.6m

Money raised

Fetch Rewards is a mobile shopping platform for earning points and rewards on purchases.

7

Funding Rounds

$135.6m

Money raised

Tasso is a Seattle-based manufacturer and supplier of blood-based diagnostic tools.

5

Funding Rounds

$530.0k

Money raised

Holos is a company developing a content management system (CMS) for virtual reality applications in education, training and development, and command centers. The company is based in Madison, Wisconsin.

5

Funding Rounds

$23.2m

Money raised

EnsoData is a Madison, Wisconsin-based technology company founded by Sam Rusk.

1

Funding Rounds

Promega is a Madison, Wisconsin-based biotechnology company developing products for research, drug discovery, forensics, paternity testing, and diagnostic applications.

2

Funding Rounds

$8.0m

Money raised

EatStreet is a Madison, Wisconsin-based company founded in 2010 by Matt Howard.

12

Funding Rounds

$30.0m

Money raised

Silatronix is a Madison, Wisconsin-based company founded in 2007 by Robert Hamers and Robert West.

3

Funding Rounds

$87.0m

Money raised

An API for healthcare in Madison that focuses on the intersection of technology and healthcare.

1

Funding Rounds

$325.0k

Money raised

ABODO is a Madison, Wisconsin-based real estate company founded in 2012 by Alec Slocum, Chad Aldous and Adam Olien.

6

Funding Rounds

$23.5m

Money raised

StudyBlue is a company that provides online flashcards and class notes.

1

Funding Rounds

$187.3k

Money raised

A research and development company focused on drug discovery for human health therapies

7

Funding Rounds

$8.4m

Money raised

Wellbe is a Madison, Wisconsin-based company founded in 2009 by James Dias.

4

Funding Rounds

$74.9m

Money raised

Virent Energy Systems is a Madison, Wisconsin-based renewable fuel source company.

3

Funding Rounds

$30.1m

Money raised

Developer of a hyper-local apartment platform designed to connect renters and property managers. The company's platform provides localized flat listing services, search aids, map-based searches, and shortlisting tools to browse through apartment listings.

2

Funding Rounds

$17.7m

Money raised

Phyllo provides APIs to access creator economy platform data.

1

Funding Rounds

$25.0m

Money raised

A company developing molecular diagnostic tests and reagents for DNA and RNA analysis

5

Funding Rounds

$8.9m

Money raised

Platypus Technologies, LLC is a comany that priovides support to scientists who push the boundaries of discovery.

3

Funding Rounds

$35.6m

Money raised

Moxe Health is a Madison, Wisconsin-based company developing technology to assist in bi-directional clinical data exchanges between healthcare providers and insurance plan providers.

4

Funding Rounds

$21.0m

Money raised

Understory is a weather pattern tracking company founded in 2012 by Bryan Dow.

5

Funding Rounds

$52.2m

Money raised

VEDA Data Solutions is a company founded by Bob Lindner.

2

Funding Rounds

$500.0k

Money raised

PeptiMed, Inc. is a Madison, Wisconsin-based biotechnology company that develops therapeutic drugs targeting the EVI1 gene for the treatment of skin, breast, lung, prostate, and ovarian cancers.

1

Funding Rounds

$550.0m

Money raised

Catalent America is a company that provides superior drug delivery technologies.

1

Funding Rounds

Murfie is a company founded in 2011 by Matt Younkle, Jason Gullickson, Steve Faulkner and Preston Austin.

2

Funding Rounds

$2.6m

Money raised

A company that builds human cellular models for toxicity screening of drug candidates, chemical compounds, cosmetic and tobacco ingredients

2

Funding Rounds

$668.0k

Money raised

Vidmaker is a Madison, Wisconsin-based company founded in 2011 by Dale Emmons, Ryan Bolyard and Yuri Zapuchlak.

1

Funding Rounds

$145.0k

Money raised

Co-D Therapeutics, Inc. is an innovative drug development company.

2

Funding Rounds

$9.5m

Money raised

Culina Health provides virtual nutrition care through registered dietitians for patients.

3

Funding Rounds

$48.5m

Money raised

Propeller Health is a Madison, Wisconsin-based company offering sensors, mobile apps, analytics and services to support respiratory health management.

5

Funding Rounds

$32.9m

Money raised

FluGen is a vaccines & Adjuvants founded in 2007 by Paul Radspinner, Gabriele Neumann and Yoshihiro Kawaoka.

2

Funding Rounds

$29.0m

Money raised

DataChat Inc. is a company founded in 2017 by Rogers Jeffrey Leo John.

1

Funding Rounds

$1.6m

Money raised

Cultured Decadence is a Wisconsin-based cellular agriculture company using cell culture and tissue engineering technologies to make lobster meat directly from the animal's cells. The company was acquired by Upside Foods in January 2022.

4

Funding Rounds

$5.6m

Money raised

Spin is a live streaming and live shopping platform designed to bring e-commerce into live streaming.

2

Funding Rounds

$7.7m

Money raised

Gregor Diagnostics is a Madison, Wisconsin-based molecular diagnostics company developing screenings for prostate cancer.

1

Funding Rounds

$2.9m

Money raised

Capio Biosciences is a Madison, Wisconsin-based medical diagnostics company offering biomarker kits for oncologists founded in 2015 by Andrew Wang.

1

Funding Rounds

$45.0m

Money raised

Veda is a Sydney-based healthcare company founded in 2015.

Industries:

Location:

1

Funding Rounds

$850.0k

Money raised

Regenerative Medical Solutions is a diabetes therapeutics using stem cell technology company founded by Anthony Kolton, Jon S. Odorico and Gary J. Gorman.

1

Funding Rounds

$13.0m

Money raised

DotCom Therapy is a company founded in 2015 by Rachel Mack Robinson.

1

Funding Rounds

$6.0m

Money raised

healthfinch is a Madison, Wisconsin-based company founded in 2011 by Jonathan Baran.

1

Funding Rounds

$1.0m

Money raised

A company providing solutions for dysphagia and other swallowing related disorders

1

Funding Rounds

$15.0m

Money raised

HealthMyne is a Madison, Wisconsin-based company founded in 2013.

3

Funding Rounds

$80.5m

Money raised

Northstar Medical Radioisotopes, Llc is a Madison, Wisconsin-based company developing products and technologies for medical diagnostics founded in 2006.

1

Funding Rounds

$800.0k

Money raised

PerBlue is a Madison, Wisconsin-based company founded by Forrest Woolworth.

3

Funding Rounds

$4.3m

Money raised

Kilter is a charity supporter engagement platform founded in 2016.

1

Funding Rounds

$3.0m

Money raised

Tetra Defense is a leading incident response, cyber risk management and digital forensics firm.

1

Funding Rounds

$13.2m

Money raised

BrainXell is a company founded in 2015.

1

Funding Rounds

$1.2m

Money raised

Intuitive Biosciences is a company developing and offering immunoassay platform founded in 2012.

2

Funding Rounds

$4.6m

Money raised

BluDiagnostics is a Madison, Wisconsin-based company developing tests for fertility testing and founded in 2012 by Douglas Weibel, Jodi Schroll and Katie Brenner.

2

Funding Rounds

$445.0k

Money raised

SciArt Software is a Madison, Wisconsin-based company founded by Praveen Yadav.

1

Funding Rounds

$1.7m

Money raised

A oncology-based pharmaceutical company developing therapeutics for the protection of cancer patients from radiotherapy and chemotherapy side effects

1

Funding Rounds

$1.4m

Money raised

A company developing system products for unmet needs in the fields of biotechnology and life science research

1

Funding Rounds

$12.0m

Money raised

A biotechnology company developing molecular reagent products and software for research and diagnostics

1

Funding Rounds

$1.5m

Money raised

Quintessence Biosciences is a phase I oncology drug company founded by Laura Strong.

1

Funding Rounds

$2.5m

Money raised

GrocerKey is a Madison, Wisconsin-based company founded in 2014.

1

Funding Rounds

$875.0k

Money raised

Semba Biosciences is a continuous SMB chromatography equipment founded in 2005.

1

Funding Rounds

$3.0m

Money raised

Invenra is an antibodies and their derivatives.

3

Funding Rounds

$10.0m

Money raised

Imbed Biosciences is a wound Dressings.

6

Funding Rounds

$21.9m

Money raised

Imbed Biosciences Inc is a Madison, Wisconsin-based company founded in 2011.

Location:

1

Funding Rounds

Madison Vaccines is a Madison, Wisconsin-based company.

1

Funding Rounds

$6.0m

Money raised

Avid Ratings is a Madison, Wisconsin-based company founded in 1992 by Paul Cardis.

6

Funding Rounds

$1.3m

Money raised

Integrated Vital Medical Dynamics, LLC is a Madison, Wisconsin-based company founded in 2014.

Location:

1

Funding Rounds

$80.0m

Money raised

Mobile shopping platform where users earn and redeem rewards.

2

Funding Rounds

$694.9k

Money raised

Re Mixers, Inc. is a Madison, Wisconsin-based company founded in 2016.

Location:

1

Funding Rounds

$4.1m

Money raised

Diamond Ridge Apartments, LLC is a company in the hospitality industry founded in 2019.

1

Funding Rounds

$37.5k

Money raised

Acellular biomaterial for delivery of cell therapy to heart

1

Funding Rounds

$7.0m

Money raised

Onlume is a fluorescence image-guided surgery founded in 2015.

2

Funding Rounds

$27.7m

Money raised

Flexcompute Inc is a Madison, Wisconsin-based company.

Location:

1

Funding Rounds

$864.8k

Money raised

SmartUQ is a Madison, Wisconsin-based company.

1

Funding Rounds

$2.0m

Money raised

Wellbe, Inc. is a Madison, Wisconsin-based company founded in 2009.

2

Funding Rounds

$325.0k

Money raised

Otologic Technologies, Inc. is a Madison, Wisconsin-based company founded in 2019.

Location:

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