69 Best Startups in Pittsburgh to Watch in 2025

The Definitive Seedtable Ranking of Startups in Pittsburgh

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 194 start-ups with an aggregate funding of $6.4b. The average funding per company in this subset is $92.5m.

Last update to the database: Feb 18, 2025. See changelog.

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10

Funding Rounds

$588.1m

Money raised

Shield AI is a company building artificially intelligent systems like drones for use by military service members and first responders.

2

Funding Rounds

$35.7m

Money raised

ForAllSecure is a Pittsburgh-based cybersecurity company developing autonomous cybersecurity tools to find and fix vulnerabilities in run-time executable software both pre-production and once deployed.

10

Funding Rounds

$5.7m

Money raised

Bloomfield Robotics is a Pittsburgh-based agricultural technology company.

8

Funding Rounds

$11.6m

Money raised

RoadBotics is a Pittsburgh-based artificial intelligence company.

1

Funding Rounds

$465.0k

Money raised

InsightStudios is a startup studio founded in 2021 by Dave Linhardt.

4

Funding Rounds

$1.8m

Money raised

Marinus Analytics is an artificial intelligence company that uses AI to disrupt human trafficking, child abuse, and cyber fraud.

1

Funding Rounds

$594.0k

Money raised

Carnegie Robotics is a Pittsburgh-based company that provides advanced robotics sensors and platforms.

6

Funding Rounds

$22.1m

Money raised

A company that had a wait list mobile application that was used in restaurants by owners and customers alike. It was founded in 2010 and acquired by Yelp in March 2017.

1

Funding Rounds

$7.5m

Money raised

Epistemix is a Pittsburgh-based provider of analytical and data modeling tools to simulate how diseases, ideas, and behaviors spread through the simulation of populations to help manage risk and shape future outcomes.

4

Funding Rounds

$212.0m

Money raised

Astrobotic Technology is a company that looks to offer affordable space robotic technology as well as work towards planetary missions.

2

Funding Rounds

$108.0m

Money raised

Petuum helps companies create artificial intelligence/machine learning solutions.

3

Funding Rounds

$60.0m

Money raised

A medical device company for patients with respiratory failure. Developing the Hemolung Respiratory Assist System (RAS), a dialysis-like alternative or supplement to mechanical ventilation.

1

Funding Rounds

$2.7m

Money raised

RociFi Labs is a multi-chain platform for cryptocurrency lending founded in 2021.

4

Funding Rounds

$1.1m

Money raised

LeanFM Technologies is a Pittsburgh-based software-as-a-service company offering artificial intelligence modelling for HVAC systems.

5

Funding Rounds

$129.3m

Money raised

Gecko Robotics is helping the world’s most important organizations ensure the availability, reliability, and sustainability of critical infrastructure.

1

Funding Rounds

A company offering cloud artificial intelligence-based video analytics that uses custom-developed neural networks which are primarily trained to detect people and vehicles. It was founded in 2018 and is located in Pittsburgh, Pennsylvania.

5

Funding Rounds

$18.4m

Money raised

Provider of an application for rideshare and taxi drivers. The company's application provides data related to locations and places and offers predictive insights to help drivers.

7

Funding Rounds

$4.6m

Money raised

Sharp Edge Labs is a US-based biotechnology company that develops drugs for protein trafficking disorders.

7

Funding Rounds

$24.6m

Money raised

Jazz is a company founded in 2009 by Don Charlton.

2

Funding Rounds

$3.6b

Money raised

Argo AI is a Pittsburgh-based artificial intelligence and self-driving technology platform company.

4

Funding Rounds

$11.6m

Money raised

Carnegie Speech Assessment provides a quick, comprehensive and cost-effective English assessment solution that optimizes hiring decisions, performs quality assurance testing, and measures language training effectiveness.

1

Funding Rounds

$100.0k

Money raised

flyRuby.com is an AI-based private jet booking platform.

5

Funding Rounds

$39.0m

Money raised

Idelic integrates all fleet data systems into an industry leading driver watch list so fleets can identify at-risk drivers and prevent accidents.

3

Funding Rounds

$34.0m

Money raised

Edge Case Research is a Pittsburgh-based company that provides tools to enhance autonomous vehicles.

5

Funding Rounds

$12.5m

Money raised

American Robotics, Inc. is a company founded in 2012 by Eitan Babcock, Reese Mozer and Vijay Somandepalli.

5

Funding Rounds

$50.9m

Money raised

Panopto is a Seattle-based company founded in 2007.

5

Funding Rounds

$8.5m

Money raised

RE2 Robotics is a company that develops intelligent mobile manipulation systems.

9

Funding Rounds

$91.7m

Money raised

Metafy is a platform that enables online players in the world to monetize their talent through 1:1 coaching and courses.

7

Funding Rounds

$34.4m

Money raised

BodyMedia is a Pittsburgh-based company founded in 2001 by Ivo Stivoric.

Location:

Key people:

7

Funding Rounds

$3.8m

Money raised

Identified Technologies developed commercial drone solutions for industrial companies to map and track job sites.

2

Funding Rounds

$271.7k

Money raised

Trademark Vision is an image recognition and AI for brand protection founded by Sandra Mau.

4

Funding Rounds

$140.0m

Money raised

Aquion Energy is a company that manufactures sodium ion batteries and energy storage systems.

4

Funding Rounds

$65.0m

Money raised

Avere Systems was a Pittsburgh-based company providing NFS and SMB file-based storage for Linux and Windows clients running in cloud, hybrid, and on-premises environments. The company was acquired by Microsoft in February 2018.

5

Funding Rounds

$19.0m

Money raised

Aspinity is a Pittsburgh-based company founded in 2018 by Brandon Rumberg, Thomas Doyle, David Graham, Tom Doyle and Dr. Brandon Rumberg.

1

Funding Rounds

$20.0m

Money raised

4moms is a Pittsburgh-based company founded in 2005.

9

Funding Rounds

$355.6m

Money raised

Anki is a robotics company founded in 2010 by Boris Sofman, Mark Palatucci and Hanns Tappeiner.

6

Funding Rounds

$40.6m

Money raised

RedZone Robotics is a company founded in 1987.

6

Funding Rounds

$6.6m

Money raised

Discover the advantage of Liquid X® metallic inks:pushing the boundaries of functional electronics fabrication by enabling additive manufacturing techniques

4

Funding Rounds

$20.5m

Money raised

IAM Robotics developed autonomous mobile robots for material handling.

5

Funding Rounds

$29.1m

Money raised

OtterTune, Inc. is an AI-Powered Database Admin founded in 2020 by Andy Pavlo.

2

Funding Rounds

$7.9m

Money raised

First Insight is a company founded in 1994.

2

Funding Rounds

$11.1m

Money raised

Voci Technologies is a company founded in 2010.

2

Funding Rounds

$12.5m

Money raised

Artificial Intelligence company

2

Funding Rounds

$22.5m

Money raised

Periphagen is a biopharmaceutical company founded in 2012 by Darren Wolfe

1

Funding Rounds

$120.0k

Money raised

A company developing lipid-based therapies for the treatment of bladder syndromes

3

Funding Rounds

$108.6m

Money raised

RoadRunner Recycling is a company founded in 2014.

1

Funding Rounds

$4.1m

Money raised

Four Growers is an industrial automation company developing harvesting robots for greenhouses.

1

Funding Rounds

$1.0m

Money raised

Navigation & Sensing For Autonomous Flight

Location:

2

Funding Rounds

$8.0m

Money raised

Kaarta offers real-time localization and mapping services.

1

Funding Rounds

$1.1m

Money raised

Skycision is a company founded in 2015.

1

Funding Rounds

$25.0k

Money raised

A company providing network performance data from the user layer to detect and solve issues on wired and WiFi network

3

Funding Rounds

$50.0k

Money raised

Rapid Flow Technologies is a company that aims to improve peoples' lives by using artificial intelligence to reimagine traffic control.

4

Funding Rounds

$30.5m

Money raised

LyGenesis is an organic regeneration using lymph nodes company founded in 2017 by Michael Hufford, Eric Lagasse and Paulo Fontes.

2

Funding Rounds

$21.8m

Money raised

Plextronics is an organic solar cells and OLED's founded in 2002.

Location:

2

Funding Rounds

$45.4m

Money raised

Blue Belt Technologies is a medical device company.

Location:

Key people:

10

Funding Rounds

$3.8m

Money raised

Blade Diagnostics is a company which makes sensor-based predictive maintenance and engineering support tools for the aerospace sector

3

Funding Rounds

$8.9m

Money raised

A diagnostics company using tissue analysis for cancer diagnosis and prognosis

2

Funding Rounds

$77.0m

Money raised

Seegrid is a Pittsburgh-based company founded in 2003 by Hans Moravec.

1

Funding Rounds

$600.0k

Money raised

Carmolex is a drug discovery company founded in 2012 by Rafael Velez.

Location:

Key people:

2

Funding Rounds

$50.0k

Money raised

HEBI Robotics’ focuses includes robotics, hardware, and software, with a core focus on motion control.

3

Funding Rounds

$46.8m

Money raised

Peptilogics is a company founded by Jonathan Steckbeck.

11

Funding Rounds

$9.7m

Money raised

Anglr is a company founded by Nicholas Wilson.

1

Funding Rounds

Fitt is a Pittsburgh-based company founded in 2017.

Industries:

Location:

3

Funding Rounds

$23.0m

Money raised

Locomation, Inc. is a Pittsburgh-based company founded in 2016.

1

Funding Rounds

$10.0m

Money raised

A diagnostic imaging services company delivering on-site radiology and teleradiology solutions

1

Funding Rounds

$15.0m

Money raised

Noveome Biotherapeutics, Inc. is a biotechnology research company focused on therapies for the regenerative repair of inflamed or damaged tissue.

Location:

1

Funding Rounds

$33.0m

Money raised

Helomics is a Pittsburgh-based company developing liver cancer detection kits founded in 1995 by Paul L. Kornblith.

1

Funding Rounds

$60.0m

Money raised

Confluence is a Pittsburgh-based company founded in 1991.

Location:

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