49 Best Alternative Fuel Startups to Watch in 2025

The Definitive Seedtable Ranking of Alternative Fuel Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 49 start-ups with an aggregate funding of $6.5b. The average funding per company in this subset is $133.0m.

Last update to the database: Feb 18, 2025. See changelog.

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Arzeda logo

Arzeda

Arzeda is a biotechnology and software company designing custom microorganisms for industrial applications through computational enzyme design, protein optimization, and metabolic engineering.

5

Funding Rounds

$72.2m

Money raised

Genomatica logo

Genomatica

Genomatica is a San Diego-based company founded in 2000 by Christophe Schilling.

10

Funding Rounds

$635.4m

Money raised

Viridos logo

Viridos

Viridos is applying synthetic biology to microalgae for the production of products that address climate change and sustainability. Viridos is focused on producing algal biofuels and other sustainable resources from algae.

8

Funding Rounds

$175.0m

Money raised

Accelergy logo

Accelergy

Accelergy is a developer of low carbon, synthetic distillate liquids and transportation fuels at a lower cost to the environment and the consumer.

4

Funding Rounds

$50.3m

Money raised

LanzaTech logo

LanzaTech

A New Zealand industrial biotechnology company developing a gas fermentation platform for converting concentrated industrial emissions into valuable chemicals.

6

Funding Rounds

$265.4m

Money raised

Joule (company) logo

Joule (company)

A biotechnology company that specialized in the renewable energy sector. It was located in Bedford, Massachusetts and is no longer in operation.

5

Funding Rounds

$225.0m

Money raised

Anellotech logo

Anellotech

Anellotech is a Pearl River, New York-based biorefinery company founded in 2008 by David Sudolsky.

7

Funding Rounds

$23.5m

Money raised

Xylogenics logo

Xylogenics

Xylogenics is a biofuels production company that uses yeast genomics founded in 2008 by Joshua Heyen.

1

Funding Rounds

$300.0k

Money raised

Nikola Motor Company logo

Nikola Motor Company

Nikola Motor Company is a Phoenix, Arizona-based automotive company founded in 2014 by Trevor Milton.

5

Funding Rounds

$2.7b

Money raised

Agrivida logo

Agrivida

An agricultural biotechnology company producing renewable, biomass-based fuels and raw materials

5

Funding Rounds

$65.4m

Money raised

Mascoma logo

Mascoma

Mascoma, founded in 2006, was a biotechnology company that made advanced bioconversion products. It was acquired by Lallemand in late 2014.

2

Funding Rounds

$91.0m

Money raised

Qteros logo

Qteros

A biotechnology and energy company developing processing technologies for clean transportation fuels.

4

Funding Rounds

$87.0m

Money raised

Sapphire Energy logo

Sapphire Energy

Developing technologies to produce jet fuel and other biofuels from algae

2

Funding Rounds

$85.0m

Money raised

Algenol logo

Algenol

An industrial biotechnology company developing an algae technology platform for producing ethanol and other biofuels.

1

Funding Rounds

$25.0m

Money raised

Global Bioenergies logo

Global Bioenergies

Global Bioenergies is a Évry, Essonne-based company founded in 2008.

6

Funding Rounds

$61.6m

Money raised

Sylvatex logo

Sylvatex

Sylvatex is a company that develops renewable materials through their nano-chemistry platform

3

Funding Rounds

Alliance BioEnergy logo

Alliance BioEnergy

Alliance BioEnergy is a company founded in 2007.

3

Funding Rounds

$6.2m

Money raised

Iogen Corporation logo

Iogen Corporation

A biotechnology company developing technologies to make biofuels from agricultural residues and organic waste products.

1

Funding Rounds

Enerkem logo

Enerkem

Enerkem is a Quebec-based company producing biofuels and renewable chemicals made from non-recyclable waste.

2

Funding Rounds

$302.7m

Money raised

Bloom Energy logo

Bloom Energy

Bloom Energy is a San Jose, California-based hydrogen fuel cell company offering on-site power generation systems.

1

Funding Rounds

$130.0m

Money raised

Intelligent Energy logo

Intelligent Energy

Intelligent Energy is a fuel cell engineering company focused on the development of its fuel cell technologies.

1

Funding Rounds

$21.0m

Money raised

Virent Energy Systems logo

Virent Energy Systems

Virent Energy Systems is a Madison, Wisconsin-based renewable fuel source company.

4

Funding Rounds

$74.9m

Money raised

H2O Innovation logo

H2O Innovation

H2O Innovation is a Quebec-based company offering water technologies and services.

6

Funding Rounds

$59.3m

Money raised

POET (company) logo

POET (company)

POET is an american biofuel company founded in 1987 by Jeff Broin.

3

Funding Rounds

$53.8m

Money raised

Fulcrum Bioenergy logo

Fulcrum Bioenergy

Fulcrum Bioenergy is a Pleasanton, California-based biofuel and clean technology company.

8

Funding Rounds

$181.0m

Money raised

Primordial Genetics logo

Primordial Genetics

Primordial Genetics is a company that is working to become a provider of genetic solutions.

3

Funding Rounds

$1.2m

Money raised

SG Biofuels logo

SG Biofuels

SG Biofuels is a biotechnology company developing renewable fuels.

3

Funding Rounds

$37.4m

Money raised

LS9 Inc logo

LS9 Inc

Uses synthetic biology to develop biofuels from traditional feedstocks

5

Funding Rounds

$105.0m

Money raised

Electrochaea logo

Electrochaea

Electrochaea has developed a commercially viable solution for utility-scale energy storage grid balancing and carbon reuse. Their proprietary process converts low-cost and stranded electricity and carbon dioxide into pipeline-grade renewable gas for direct injection into the existing natural gas grid a conversion process known as "power-to-gas".

2

Funding Rounds

$17.3m

Money raised

3Degrees logo

3Degrees

3Degrees is a San Francisco-based provider of carbon offset and renewable energy services and solutions.

2

Funding Rounds

$4.0m

Money raised

Bio Architecture Lab logo

Bio Architecture Lab

Bio Architecture Lab is a company and pioneer in the application of synthetic biology.

8

Funding Rounds

$39.7m

Money raised

Pond Technologies logo

Pond Technologies

Pond Technologies is a Markham-based developer of algae based carbon capture technologies which processes their algae production into nutraceuticals, animal feed, and petroleum derivatives.

7

Funding Rounds

$13.8m

Money raised

Neoprospecta logo

Neoprospecta

Neoprospecta is an enzyme discovery and development company founded by Luiz Felipe Valter de Oliveira, Marcos De Carvalho and Ronaldo Mota.

2

Funding Rounds

$900.0k

Money raised

FreshFry logo

FreshFry

FreshFry is a Louisville, Kentucky-based company founded by Jeremiah Chapman.

2

Funding Rounds

$3.3m

Money raised

CERT logo

CERT

CERT is a Toronto-based carbon capture and storage company converting CO2 into chemical feedstocks and carbon-based fuels.

1

Funding Rounds

$1.4m

Money raised

BioIntelligence Technologies.inc. logo

BioIntelligence Technologies.inc.

BioIntelligence Technologies.inc. is a software development company for biotechnology founded by Joel Sirois.

2

Funding Rounds

$1.0m

Money raised

AFC Energy logo

AFC Energy

AFC Energy is a provider of alkaline fuel cell systems using hydrogen for electricity production.

1

Funding Rounds

$20.0m

Money raised

Sunchem logo

Sunchem

Sunchem is an Amsterdam-based developer of biofuels, sustainable feed production, sustainable food and biopharmaceuticals.

1

Funding Rounds

$1.3m

Money raised

Nexterra logo

Nexterra

Nexterra is a Vancouver-based company operating gasification systems to self-generate clean, low cost heat and power through waste fuels.

3

Funding Rounds

$14.0m

Money raised

Propel Biofuels logo

Propel Biofuels

Propel Biofuels is a sells biodiesel and E85 ethanol blends founded in 2004 by Rob Elam.

1

Funding Rounds

$11.0m

Money raised

ZeaChem logo

ZeaChem

ZeaChem is a Lakewood, Colorado-based company founded in 2002.

3

Funding Rounds

$63.0m

Money raised

InSymbio logo

InSymbio

InSymbio is a Salerno-based company founded by Stefano Esposito.

1

Funding Rounds

$121.7k

Money raised

Red Rock Biofuels logo

Red Rock Biofuels

Red Rock Biofuels is a Fort Collins, Colorado-based manufacturer of biofuels.

1

Funding Rounds

Gammakat Logistic logo

Gammakat Logistic

Gammakat Logistic is a company founded by Uwe Rolli that specializes in recycling.

1

Funding Rounds

$3.2k

Money raised

Novogy logo

Novogy

Novogy is a Cambridge, Massachusetts-based company founded by Ginja Silva.

3

Funding Rounds

$754.8m

Money raised

TeraPore Technologies logo

TeraPore Technologies

TeraPore Technologies is a Cornell University spinout that develops and manufactures high performance filters for protein separations.

2

Funding Rounds

Woodland Biofuels logo

Woodland Biofuels

Woodland Biofuels is a Toronto-based producer of biofuels and ethanols from waste biomass including wood chips and agricultural waste.

1

Funding Rounds

$1.2m

Money raised

1

Funding Rounds

$16.9m

Money raised

BioFuelBox Corporation logo

BioFuelBox Corporation

Makes a modular container that produces biofuel cost-effectively

1

Funding Rounds

$5.2m

Money raised