69 Best Startups in Ann Arbor Michigan to Watch in 2025

The Definitive Seedtable Ranking of Startups in Ann Arbor Michigan

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 89 start-ups with an aggregate funding of $2.1b. The average funding per company in this subset is $29.7m.

Last update to the database: Feb 18, 2025. See changelog.

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3

Funding Rounds

$53.1m

Money raised

Censys is an Ann Arbor, Michigan-based computer and network security company.

4

Funding Rounds

$14.0m

Money raised

A biotechnology company developing and commercializing spider silk for textiles and performance polymers. Kraig Biocraft Laboratories uses genetic engineering to produce recombinant spider silk based fibers on an industrial scale.

1

Funding Rounds

XanEdu is a publishing company that offers custom course materials.

2

Funding Rounds

$71.5m

Money raised

Now known as Sierra Oncology, is a clinical stage drug development company in Vancouver that focuses on cancer and hematology treatments.

9

Funding Rounds

$138.9m

Money raised

SkySpecs is a company founded in 2012 by Daniel Ellis.

1

Funding Rounds

$1.5m

Money raised

Cayman Chemical Company is an Ann Arbor, Michigan-based biotechnology company manufacturing healthcare and research diagnostic tools including assay kits, antibodies, proteins, and biochemicals.

4

Funding Rounds

$59.8m

Money raised

Clinc is a company with an artificial intelligence platform that looks to enable enterprises to create virtual assistants

5

Funding Rounds

$109.0m

Money raised

Upstream Security is an artificial intelligence company founded by Yoav Levy that develops automotive cloud security software.

5

Funding Rounds

$188.5m

Money raised

A company developing autonomous vehicles for central business districts, enterprise campuses and residential communities

1

Funding Rounds

$20.0m

Money raised

GENOMENON is an Ann Arbor, Michigan-based company founded in 2014.

3

Funding Rounds

$10.3m

Money raised

ArborMetrix is an Ann Arbor, Michigan-based company founded in 2011.

3

Funding Rounds

$3.1m

Money raised

Derq is an MIT spinoff that uses AI to power an award-winning predictive platform, help eliminate crashes and create safer and smarter roads.

4

Funding Rounds

$140.3m

Money raised

StrataOncology is a tumor sequencing for therapeutic targeting founded in 2015 by Dan Rhodes, Dan Rhodes and Scott Tomlins.

5

Funding Rounds

$164.3m

Money raised

ONL Therapeutics (ONL) is a clinical-stage biopharmaceutical company committed to helping patients see the future.

1

Funding Rounds

Olark provides a live chat platform that enables enterprises to talk to customers browsing their website.

1

Funding Rounds

$8.0m

Money raised

Xoran Technologies is an Ann Arbor, Michigan-based company.

8

Funding Rounds

$34.7m

Money raised

Swift Biosciences is a biotechnology company founded in 2010 by Timothy Harkins.

2

Funding Rounds

$100.0k

Money raised

Elegus Technologies is an Ann Arbor, Michigan-based company founded by Long Qian, Siuon Tung, Nicholas Kotov and John Hennessy.

7

Funding Rounds

$123.8m

Money raised

A company focused on developing immunotherapy treatments for autoimmune disease and cancer

6

Funding Rounds

$50.2m

Money raised

Sakti3 is a company that operates as a leader in the solid state battery technology.

1

Funding Rounds

$750.0k

Money raised

Nutshell is an Ann Arbor, Michigan-based company founded in 2009 by Guy Suter, Andy Fowler and Ian Berry.

1

Funding Rounds

$2.0m

Money raised

Forever Labs is a stem cells storage company founded in 2015 by Michael Elfassy, Benjamin Buller and Steven Clausnitzer.

1

Funding Rounds

$5.0m

Money raised

Billy is a company making smart home technologies to help seniors live independently.

2

Funding Rounds

$3.3m

Money raised

Voxel51 is an artificial Intelligence company founded in 2016 by Jason Corso.

1

Funding Rounds

$250.0k

Money raised

SensiGen is a company developing and commercializing gene-based molecular diagnostic tests for the early detection of diseases.

1

Funding Rounds

$4.2m

Money raised

Refraction AI is a robotic-enabled delivery technology company and manufacturer.

3

Funding Rounds

$2.6m

Money raised

Arbor Photonics is an Ann Arbor, Michigan-based company founded by Almantas Galvanauskas.

1

Funding Rounds

$1.0m

Money raised

Ecovia Renewables is a polyglutamic acid production company founded in 2014.

1

Funding Rounds

$9.4m

Money raised

A company offering an electric unmanned aircraft for first responder surveillance.

2

Funding Rounds

$5.5m

Money raised

Rubicon Genomics is a company that develops nucleic acid library preparation and companion products for the analysis of clinical research samples

2

Funding Rounds

$3.0m

Money raised

Biotectix focuses on the development of bioactive conductive polymer electrodes and coatings for electrodes for medical devices.

5

Funding Rounds

$334.0m

Money raised

PROGENITY, INC is a provider of specialized genetic testing services.

2

Funding Rounds

$300.0k

Money raised

New Eagle is an Ann Arbor, Michigan-based mechatronic control systems company founded in 2008.

3

Funding Rounds

$120.0k

Money raised

PreDxion Bio is a precision medicine diagnostics company founded in 2017 by Caroline Landau, Walker McHugh and Timothy Cornell.

4

Funding Rounds

$131.1m

Money raised

Provider of an online addiction recovery program intended to deliver improved addiction care through technology, experience, and design.

2

Funding Rounds

$12.9m

Money raised

Company

6

Funding Rounds

$30.6m

Money raised

A medical device company developing cytometers

2

Funding Rounds

$7.5m

Money raised

Kumanu, previously JOOL Health, is an Ann Arbor, Michigan-based software development company offering a wellbeing platform for individuals, teams, and organizations.

1

Funding Rounds

$17.5m

Money raised

Akadeum Life Sciences, Inc. is an Ann Arbor, Michigan-based life sciences company founded in 2014.

2

Funding Rounds

$11.0m

Money raised

Trove Ai is an Ann Arbor, Michigan-based company founded in 2013 by Ian Berry.

1

Funding Rounds

$4.0m

Money raised

AdAdapted is an Ann Arbor, Michigan-based company founded in 2012.

2

Funding Rounds

$1.1m

Money raised

Seelio is an Ann Arbor, Michigan-based company founded in 2011 by Moses K. Lee, Chris Baik and David Jsa.

1

Funding Rounds

$20.0m

Money raised

ForeSee is an Ann Arbor, Michigan-based company founded in 2001.

1

Funding Rounds

$21.0m

Money raised

NeuMoDx Molecular is an Ann Arbor, Michigan-based medical diagnostics company developing molecular diagnostics testing.

3

Funding Rounds

$3.5m

Money raised

Atomic Object is a company founded in 2001.

1

Funding Rounds

$1.5m

Money raised

A company providing three-dimensional cell culture solutions for drug discovery, cancer research and other life sciences research

1

Funding Rounds

$3.6m

Money raised

Invisible AI is a visual intelligence platform that works with manufacturing/assembly operators to ensure processes are done correctly.

1

Funding Rounds

$4.5m

Money raised

Accio Energy is a michigan-based distributed wind energy systems maker founded in 2007 by Dawn White.

1

Funding Rounds

NovoDynamics, Inc. is an Ann Arbor, Michigan-based company.

1

Funding Rounds

$4.6m

Money raised

RedBrick AI is a company founded in 2020 by Derek Lukacs.

1

Funding Rounds

$2.5m

Money raised

Nanocerox is an Ann Arbor, Michigan-based company.

1

Funding Rounds

Chemotherapy is the foundation of cancer treatment because it is so effective, but it is also the downfall of cancer treatment because it is so toxic. Patients can experience hair loss, nausea, fatigue, aching, or neuropathy and often find that the treatment seems worse than the disease.

Key people:

1

Funding Rounds

$16.0m

Money raised

Atterocor was a biotechnology company based in Ann Arbor, Michigan.

3

Funding Rounds

$2.3m

Money raised

CubeWorks, Inc. is an Ann Arbor, Michigan-based company.

1

Funding Rounds

$900.0k

Money raised

OcuSciences is an Ann Arbor, Michigan-based medical device company developing technologies to detect and diagnose eye diseases.

2

Funding Rounds

$24.5m

Money raised

Millendo Therapeutics is a small Molecules.

1

Funding Rounds

$1.5m

Money raised

Deepfield is an Ann Arbor, Michigan-based company founded in 2011 by Craig Labovitz.

1

Funding Rounds

$25.0m

Money raised

C3 Industries is an Ann Arbor, Michigan-based company founded in 2018 by Ankur Rungta.

1

Funding Rounds

$20.0m

Money raised

Groundspeed Analytics, Inc. is an Ann Arbor, Michigan-based company founded in 2016.

2

Funding Rounds

$16.9m

Money raised

Fifth Eye is an Ann Arbor, Michigan-based company founded in 2017.

3

Funding Rounds

$16.9m

Money raised

Tangent Medical Technologies is an Ann Arbor, Michigan-based healthcare company.

Industries:

1

Funding Rounds

$15.0m

Money raised

Danotek Motion Technologies is an Ann Arbor, Michigan-based company founded in 2001.

3

Funding Rounds

$6.0m

Money raised

NAVV Systems, Inc. is a company founded in 2018.

1

Funding Rounds

$9.5m

Money raised

Notion AI is an Ann Arbor, Michigan-based company founded by Finesh Prasad.

1

Funding Rounds

$10.0m

Money raised

Platform for developing customizable digital twin solutions for the built environment.

Location:

1

Funding Rounds

$12.0m

Money raised

Sensicore is an Ann Arbor, Michigan-based company.

1

Funding Rounds

$2.5m

Money raised

Ripple Science is an Ann Arbor, Michigan-based company founded in 2016.

1

Funding Rounds

$23.0m

Money raised

Naif Company is a company founded in 2015.

1

Funding Rounds

$9.8m

Money raised

Aquaro Biosystems is an Ann Arbor, Michigan-based company founded in 2013.

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