22 Best Startups in Champaign Illinois to Watch in 2025

The Definitive Seedtable Ranking of Startups in Champaign Illinois

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 22 start-ups with an aggregate funding of $132.1m. The average funding per company in this subset is $6.0m.

Last update to the database: Feb 18, 2025. See changelog.

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1

Funding Rounds

$5.3m

Money raised

Runtime Verification is a startup company focused on runtime verification approaches for the improvement of software systems.

2

Funding Rounds

$25.0m

Money raised

Reconstruct Inc. is a Menlo Park, California company and visual command center for construction projects offering AI-powered remote quality control, progress monitoring, and facilities assessment software.

1

Funding Rounds

$20.0m

Money raised

Intelinair is a company founded in 2015.

4

Funding Rounds

$700.0k

Money raised

Phi Optics is a company that makes an upgrade on the existing optical imaging systems.

3

Funding Rounds

$4.0m

Money raised

Natrion is a company founded in 2018 by Thomas Rouffiac.

2

Funding Rounds

$970.7k

Money raised

Vertex Solutions is a company which provides virtual training using technologies such as extended reality for pilots and key aircraft support staff in the U.S. defense and public safety sectors

1

Funding Rounds

$10.0m

Money raised

We provide in-depth farmland productivity and efficiency insights from the field level to global scale, supporting improved environmental outcomes, carbon markets, and other novel mechanisms to advance adoption of climate-smart farming practices.

1

Funding Rounds

$15.0m

Money raised

Simbiosys is a toronto-based chemistry software company founded in 2018.

Location:

6

Funding Rounds

$8.0m

Money raised

Inprentus has developed a new method for manufacturing mechanically ruled blazed diffraction gratings for synchrotron, FEL and laser applications, offering high resolving power with blaze angles lower than 1 degree.

1

Funding Rounds

$1.0m

Money raised

One Llama Media is a Champaign, Illinois-based company founded by Nikhil Pandit.

1

Funding Rounds

$4.0m

Money raised

Serionix is a biotechnology company developing color-changing air filters.

1

Funding Rounds

$3.0m

Money raised

Vanquish Oncology is a company developing targeted, small molecule oncology therapeutics founded by Ted Tarasow.

1

Funding Rounds

$5.2m

Money raised

PhotoniCare is a developer of a patented imaging platform technology that provides growth opportunities beyond otology.

Key people:

1

Funding Rounds

$250.0k

Money raised

A company drugs for the treatment of infectious diseases, cancer and autoimmune disorders

1

Funding Rounds

$1.2m

Money raised

Cazoodle is a Champaign, Illinois-based company founded in 2006 by Govind Kabra.

Industries:

Key people:

1

Funding Rounds

$6.5m

Money raised

APFusion is a Champaign, Illinois-based company.

1

Funding Rounds

$4.0m

Money raised

Company

1

Funding Rounds

$500.0k

Money raised

IntelliWheels is a Champaign, Illinois-based company.

1

Funding Rounds

$5.0m

Money raised

InterSymbol Communications is a Champaign, Illinois-based electronics company.

Industries:

1

Funding Rounds

$9.7m

Money raised

Agrible, Inc. is a Champaign, Illinois-based company founded in 2012.

1

Funding Rounds

Beta 202 Daniel Fund LLC is a Champaign, Illinois-based company founded in 2019.

1

Funding Rounds

$2.7m

Money raised

R Systems NA Inc. is a Champaign, Illinois-based company.

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