69 Best Startups in Cincinnati to Watch in 2025

The Definitive Seedtable Ranking of Startups in Cincinnati

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 99 start-ups with an aggregate funding of $2.4b. The average funding per company in this subset is $34.1m.

Last update to the database: Feb 18, 2025. See changelog.

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4

Funding Rounds

$84.9m

Money raised

Physna is a Cincinnati-based 3D modelling software company offering 3D models understandable by software applications for manufacturing, engineering, product design, 3D printing, augmented reality and virtual reality applications.

4

Funding Rounds

$70.0m

Money raised

Coterie is an API-based commercial business insurance provider that updates policy changes in real-time.

1

Funding Rounds

$2.1m

Money raised

Spatial supplies a social understanding of location, founded by Griffin Morris, Lyden Foust and Will Kiessling.

1

Funding Rounds

$10.0k

Money raised

CompleteSet is a company that acts as a world archive for collectibles, founded by Gary Darna and Jaime Rump.

3

Funding Rounds

$17.9m

Money raised

Genesis is a company that provides integrated biomagnetic solutions.

7

Funding Rounds

$201.0m

Money raised

Finix is a full-stack payment processor that develops a payment processing platform for businesses.

Key people:

4

Funding Rounds

$6.6m

Money raised

Better customer experience with Machine Learning, allowing companies to scale customer facing ops while increasing the level of customer care.

2

Funding Rounds

$4.5m

Money raised

Monetizr is a blockchain company founded by Martins Bratuskins.

2

Funding Rounds

$10.5m

Money raised

LISNR develop sultrasonic data-over-sound technology for proximity verification and contactless transactions.

1

Funding Rounds

$40.0m

Money raised

80 Acres Farms is a farming company that uses indoor farming technology.

2

Funding Rounds

$2.5m

Money raised

Roadtrippers is a Cincinnati-based company founded in 2012 by James Fisher, Tatiana Parent and John Lauck.

1

Funding Rounds

$900.0k

Money raised

Bacterial Robotics is a Cincinnati-based company.

6

Funding Rounds

$241.2m

Money raised

Astronomer helps organizations adopt Apache Airflow, an open-source data workflow orchestration platform that helps organizations get their data in motion..

1

Funding Rounds

$11.0m

Money raised

A mobile app in Ohio that focuses on healthcare.

1

Funding Rounds

$140.0m

Money raised

PatientPoint is a Cincinnati-based company founded in 1987.

1

Funding Rounds

$426.0m

Money raised

Paycor is a company founded in 1990 by Peter Swaniker.

1

Funding Rounds

CRäKN offers business solutions and technologies designed for funeral home, crematory, cemetery and other death care companies.

Location:

10

Funding Rounds

$54.6m

Money raised

A company that develops biotechnology solutions for agriculture & environmental management

1

Funding Rounds

$7.0m

Money raised

Provider of an online collaborative transaction environment for the real estate industry. The company's software simplifies the process of buying or selling a home by letting real estate agents, their clients and other service providers share, edit, sign and store documents digitally.

1

Funding Rounds

$10.0m

Money raised

Sourcebits is a company founded in 2006 by Rohit Singal.

2

Funding Rounds

$1.4m

Money raised

Developer of an ordering and payment management system designed to serve multi-location restaurants and bars. The company's system gives a total performance view and uses advanced analytics to keep informed of issues before they happen, enabling clients to deliver improved guest experiences.

2

Funding Rounds

$41.5m

Money raised

Everything But The House is a company founded in 2006 by Jacquie Denny.

2

Funding Rounds

$30.1m

Money raised

A company developing precision drug delivery systems and products

1

Funding Rounds

Kai Coach is a Cincinnati, Ohio-based startup focused on developing an AI-driven platform to help professional coaches and their clients connect.

9

Funding Rounds

$11.6m

Money raised

IncludeHealth, Inc. is a Columbus, Ohio-based company which creates fitness equipment and software tools to help trainers and physical therapists help clients and patients alleviate musculoskeletal symptoms through monitored exercise programming.

3

Funding Rounds

$3.8m

Money raised

SightGain (legal name: Cyber COAST Inc) is a cyber threat intelligence company with offices in Tysons Corner, Virginia and Cincinnati, Ohio.

1

Funding Rounds

$3.0m

Money raised

High speed resolutions to hypersonic challenges through innovative problem solving and rapid hardware development.

5

Funding Rounds

$33.8m

Money raised

A biotechnology company developing therapies for acute and chronic lung diseases in neonates

1

Funding Rounds

$5.2m

Money raised

Losant is a Cincinnati-based company founded in 2015 by Charlie Key, Brandon Cannaday and Michael Kuehl.

1

Funding Rounds

$1.4m

Money raised

10XTS is an artificial Intelligence company founded in 2017 by Michael Hiles, John Bentley, II, Robert Slater and Yogesh Kadiyala.

1

Funding Rounds

$57.5m

Money raised

Honeywell Intelligrated is a software engineering company.

1

Funding Rounds

$300.0k

Money raised

OneMorePallet is a Cincinnati-based company founded by Scott Miller.

1

Funding Rounds

$15.0m

Money raised

Measure is a company founded in 2020.

1

Funding Rounds

$310.0k

Money raised

SoMoLend is a Cincinnati-based company founded by Candace Klein.

6

Funding Rounds

$27.3m

Money raised

Eccrine Systems is a Cincinnati-based company founded in 2013 by Robert Beech.

1

Funding Rounds

$13.0m

Money raised

1

Funding Rounds

$15.0m

Money raised

Kurome Therapeutics is developing therapies that target cancer cells that have co-opted immune signaling pathways in order to avoid destruction by traditional therapeutic agents and subvert adaptive resistance mechanisms.

2

Funding Rounds

$30.0k

Money raised

Liquid is a Cincinnati-based software and mobile application builder to collect, analyze, and share data.

2

Funding Rounds

$3.5m

Money raised

Polar3D is a company that owns Polar Cloud,

3

Funding Rounds

$285.0m

Money raised

Enable Injections is a wearable Automated Injector Device founded in 2010.

1

Funding Rounds

$10.0k

Money raised

VenturePax is a Cincinnati-based company founded in 2009 by Danny Stull.

Industries:

Location:

Key people:

1

Funding Rounds

$9.1m

Money raised

Cloverleaf.me is a company founded in 2017 by Darrin Murriner.

4

Funding Rounds

$65.5m

Money raised

VNDLY, Inc is a Cincinnati-based company founded in 2017.

1

Funding Rounds

$11.0m

Money raised

Construction Software Technologies is a Cincinnati-based company founded in 1993.

2

Funding Rounds

$44.0m

Money raised

Standard Bariatrics, Inc is a bariatric Clamps founded in 2014 by Jonathan Thompson.

2

Funding Rounds

$32.0m

Money raised

A biopharmaceutical company focused on treatments for the eye

1

Funding Rounds

$4.2m

Money raised

General Nano LLC is a Cincinnati-based company.

Location:

2

Funding Rounds

$14.5m

Money raised

Mantium Inc. is a Cincinnati-based company founded in 2021 by Ryan Sevey.

2

Funding Rounds

$3.8m

Money raised

ActionStreamer is a Cincinnati-based company founded in 2015.

3

Funding Rounds

$2.2m

Money raised

GoSun Stove is a company founded in 2016 by Patrick Sherwin.

3

Funding Rounds

$26.0m

Money raised

STACK Construction Technologies is a company founded in 2012.

3

Funding Rounds

$350.0k

Money raised

BRIVAS LABS is a Cincinnati-based company founded in 2012 by Michael A. Cioffi.

1

Funding Rounds

$1.5m

Money raised

Central offers automation technology that pairs a low code integration platform with personalized "virtual assistants" for employees.

1

Funding Rounds

$13.6m

Money raised

Now Sirrus, is a company developing biologically benign monomers, resins and polymers

Location:

1

Funding Rounds

$2.0m

Money raised

Pay Theory is a Cincinnati-based company founded in 2018 by Eric Fulkert.

1

Funding Rounds

$800.0k

Money raised

batterii is a Cincinnati-based software company developing visual collaboration tools.

2

Funding Rounds

$9.0m

Money raised

Amplicore Inc. is a company founded in 2018 by Chia-Ying Lin.

1

Funding Rounds

$27.0m

Money raised

CarePoint Partners is a home infusion and specialty pharmacy provider company founded in 1999.

1

Funding Rounds

$3.8m

Money raised

Zipscene is a Cincinnati-based company founded in 2011.

Location:

1

Funding Rounds

$10.0m

Money raised

CinRx Pharma is a new Molecular Entities founded in 2015.

Location:

1

Funding Rounds

$5.5m

Money raised

Readyset Surgical is a Cincinnati-based company founded in 2014.

Location:

1

Funding Rounds

$1.8m

Money raised

Native.AI is a company founded in 2018 by FRANK PICA.

4

Funding Rounds

$4.8m

Money raised

Crakn, LLC is a Cincinnati-based company founded in 2014.

Location:

1

Funding Rounds

$1.4m

Money raised

Subterra.Ai is a Cincinnati-based cloud computing company founded in 2018.

Industries:

Location:

1

Funding Rounds

$2.5m

Money raised

Predictronics Corp. is an analytics company founded in 2019.

5

Funding Rounds

$73.0m

Money raised

Coterie Applications, Inc. is an insurance company founded in 2018.

Industries:

2

Funding Rounds

$6.4m

Money raised

Sense Diagnostics, Inc. is a Cincinnati-based company founded in 2017.

Location:

2

Funding Rounds

$97.1m

Money raised

Luma Financial Technologies, LLC is a Cincinnati-based company founded in 2018.

Location:

1

Funding Rounds

$750.0k

Money raised

CCO Technology, LLC is a Cincinnati-based company.

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