69 Best Startups in Brookline Pittsburgh to Watch in 2026

The Definitive Seedtable Ranking of Startups in Brookline Pittsburgh

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 197 start-ups with an aggregate funding of $6.1b. The average funding per company in this subset is $89.0m.

Last update to the database: Apr 7, 2026. See changelog.

Track over 71,000 companies

Discover
Fast-growing Global startups

Seedtable uses technology and people to track over 71,000 companies to help you find the right ones to partner with.

Pricing + Sign up

4

Funding Rounds

$124.8m

Money raised

Peptilogics is a company founded by Jonathan Steckbeck.

6

Funding Rounds

$254.3m

Money raised

Gecko Robotics is helping the world’s most important organizations ensure the availability, reliability, and sustainability of critical infrastructure.

Key people:

4

Funding Rounds

$212.0m

Money raised

Astrobotic Technology is a company that looks to offer affordable space robotic technology as well as work towards planetary missions.

Location:

Key people:

2

Funding Rounds

$3.6b

Money raised

Argo AI is a Pittsburgh-based artificial intelligence and self-driving technology platform company.

9

Funding Rounds

$91.7m

Money raised

Metafy is a platform that enables online players in the world to monetize their talent through 1:1 coaching and courses.

7

Funding Rounds

$67.5m

Money raised

Iralogix, Inc. is a Pittsburgh-based company founded in 2015.

Location:

10

Funding Rounds

$588.1m

Money raised

Shield AI is a company building artificially intelligent systems like drones for use by military service members and first responders.

2

Funding Rounds

$35.7m

Money raised

ForAllSecure is a Pittsburgh-based cybersecurity company developing autonomous cybersecurity tools to find and fix vulnerabilities in run-time executable software both pre-production and once deployed.

Location:

Key people:

5

Funding Rounds

$39.0m

Money raised

Idelic integrates all fleet data systems into an industry leading driver watch list so fleets can identify at-risk drivers and prevent accidents.

Location:

Key people:

3

Funding Rounds

$34.0m

Money raised

Edge Case Research is a Pittsburgh-based company that provides tools to enhance autonomous vehicles.

5

Funding Rounds

$29.1m

Money raised

OtterTune, Inc. is an AI-Powered Database Admin founded in 2020 by Andy Pavlo.

Location:

Key people:

2

Funding Rounds

$12.5m

Money raised

Artificial Intelligence company

1

Funding Rounds

$10.6m

Money raised

BlastPoint is a Pittsburgh-based company founded by Alison Alvarez.

2

Funding Rounds

$108.0m

Money raised

Petuum helps companies create artificial intelligence/machine learning solutions.

Location:

Key people:

3

Funding Rounds

$60.0m

Money raised

A medical device company for patients with respiratory failure. Developing the Hemolung Respiratory Assist System (RAS), a dialysis-like alternative or supplement to mechanical ventilation.

5

Funding Rounds

$18.4m

Money raised

Provider of an application for rideshare and taxi drivers. The company's application provides data related to locations and places and offers predictive insights to help drivers.

Location:

Key people:

4

Funding Rounds

$65.0m

Money raised

Avere Systems was a Pittsburgh-based company providing NFS and SMB file-based storage for Linux and Windows clients running in cloud, hybrid, and on-premises environments. The company was acquired by Microsoft in February 2018.

5

Funding Rounds

$19.0m

Money raised

Aspinity is a Pittsburgh-based company founded in 2018 by Brandon Rumberg, Thomas Doyle, David Graham, Tom Doyle and Dr. Brandon Rumberg.

1

Funding Rounds

$20.0m

Money raised

4moms is a Pittsburgh-based company founded in 2005.

3

Funding Rounds

$108.6m

Money raised

RoadRunner Recycling is a company founded in 2014.

2

Funding Rounds

$77.0m

Money raised

Seegrid is a Pittsburgh-based company founded in 2003 by Hans Moravec.

1

Funding Rounds

$60.0m

Money raised

Confluence is a Pittsburgh-based company founded in 1991.

Location:

6

Funding Rounds

$22.1m

Money raised

A company that had a wait list mobile application that was used in restaurants by owners and customers alike. It was founded in 2010 and acquired by Yelp in March 2017.

7

Funding Rounds

$24.6m

Money raised

Jazz is a company founded in 2009 by Don Charlton.

7

Funding Rounds

$34.4m

Money raised

BodyMedia is a Pittsburgh-based company founded in 2001 by Ivo Stivoric.

Location:

Key people:

6

Funding Rounds

$40.6m

Money raised

RedZone Robotics is a company founded in 1987.

4

Funding Rounds

$20.5m

Money raised

IAM Robotics developed autonomous mobile robots for material handling.

Key people:

2

Funding Rounds

$22.5m

Money raised

Periphagen is a biopharmaceutical company founded in 2012 by Darren Wolfe

Location:

Key people:

4

Funding Rounds

$30.5m

Money raised

LyGenesis is an organic regeneration using lymph nodes company founded in 2017 by Michael Hufford, Eric Lagasse and Paulo Fontes.

Location:

Key people:

2

Funding Rounds

$21.8m

Money raised

Plextronics is an organic solar cells and OLED's founded in 2002.

Location:

2

Funding Rounds

$45.4m

Money raised

Blue Belt Technologies is a medical device company.

Location:

Key people:

3

Funding Rounds

$23.0m

Money raised

Locomation, Inc. is a Pittsburgh-based company founded in 2016.

1

Funding Rounds

$33.0m

Money raised

Helomics is a Pittsburgh-based company developing liver cancer detection kits founded in 1995 by Paul L. Kornblith.

1

Funding Rounds

$21.0m

Money raised

Hyliion is a company founded in 2015.

10

Funding Rounds

$5.7m

Money raised

Bloomfield Robotics is a Pittsburgh-based agricultural technology company.

8

Funding Rounds

$11.6m

Money raised

RoadBotics is a Pittsburgh-based artificial intelligence company.

Location:

Key people:

1

Funding Rounds

$7.5m

Money raised

Epistemix is a Pittsburgh-based provider of analytical and data modeling tools to simulate how diseases, ideas, and behaviors spread through the simulation of populations to help manage risk and shape future outcomes.

Location:

Key people:

1

Funding Rounds

$2.7m

Money raised

RociFi Labs is a multi-chain platform for cryptocurrency lending founded in 2021.

4

Funding Rounds

$11.6m

Money raised

Carnegie Speech Assessment provides a quick, comprehensive and cost-effective English assessment solution that optimizes hiring decisions, performs quality assurance testing, and measures language training effectiveness.

5

Funding Rounds

$12.5m

Money raised

American Robotics, Inc. is a company founded in 2012 by Eitan Babcock, Reese Mozer and Vijay Somandepalli.

Key people:

5

Funding Rounds

$8.5m

Money raised

RE2 Robotics is a company that develops intelligent mobile manipulation systems.

6

Funding Rounds

$6.6m

Money raised

Discover the advantage of Liquid X® metallic inks:pushing the boundaries of functional electronics fabrication by enabling additive manufacturing techniques

2

Funding Rounds

$7.9m

Money raised

First Insight is a company founded in 1994.

2

Funding Rounds

$11.1m

Money raised

Voci Technologies is a company founded in 2010.

2

Funding Rounds

$8.0m

Money raised

Kaarta offers real-time localization and mapping services.

3

Funding Rounds

$8.9m

Money raised

A diagnostics company using tissue analysis for cancer diagnosis and prognosis

11

Funding Rounds

$9.7m

Money raised

Anglr is a company founded by Nicholas Wilson.

Key people:

1

Funding Rounds

$15.0m

Money raised

Noveome Biotherapeutics, Inc. is a biotechnology research company focused on therapies for the regenerative repair of inflamed or damaged tissue.

Location:

1

Funding Rounds

$9.3m

Money raised

MedCPU is a Pittsburgh-based company founded in 2008.

Industries:

Location:

7

Funding Rounds

$4.6m

Money raised

Sharp Edge Labs is a US-based biotechnology company that develops drugs for protein trafficking disorders.

7

Funding Rounds

$3.8m

Money raised

Identified Technologies developed commercial drone solutions for industrial companies to map and track job sites.

Location:

Key people:

1

Funding Rounds

$4.1m

Money raised

Four Growers is an industrial automation company developing harvesting robots for greenhouses.

10

Funding Rounds

$3.8m

Money raised

Blade Diagnostics is a company which makes sensor-based predictive maintenance and engineering support tools for the aerospace sector

1

Funding Rounds

$4.4m

Money raised

Kwantera is an AI-driven analytics platform provider in the energy field.

Location:

Key people:

1

Funding Rounds

$465.0k

Money raised

InsightStudios is a startup studio founded in 2021 by Dave Linhardt.

Key people:

4

Funding Rounds

$1.8m

Money raised

Marinus Analytics is an artificial intelligence company that uses AI to disrupt human trafficking, child abuse, and cyber fraud.

Location:

Key people:

1

Funding Rounds

$594.0k

Money raised

Carnegie Robotics is a Pittsburgh-based company that provides advanced robotics sensors and platforms.

Location:

Key people:

4

Funding Rounds

$1.1m

Money raised

LeanFM Technologies is a Pittsburgh-based software-as-a-service company offering artificial intelligence modelling for HVAC systems.

Location:

Key people:

1

Funding Rounds

A company offering cloud artificial intelligence-based video analytics that uses custom-developed neural networks which are primarily trained to detect people and vehicles. It was founded in 2018 and is located in Pittsburgh, Pennsylvania.

1

Funding Rounds

$100.0k

Money raised

flyRuby.com is an AI-based private jet booking platform.

2

Funding Rounds

$271.7k

Money raised

Trademark Vision is an image recognition and AI for brand protection founded by Sandra Mau.

Location:

Key people:

1

Funding Rounds

$120.0k

Money raised

A company developing lipid-based therapies for the treatment of bladder syndromes

1

Funding Rounds

$1.0m

Money raised

Navigation & Sensing For Autonomous Flight

Location:

1

Funding Rounds

$25.0k

Money raised

A company providing network performance data from the user layer to detect and solve issues on wired and WiFi network

Location:

Key people:

3

Funding Rounds

$50.0k

Money raised

Rapid Flow Technologies is a company that aims to improve peoples' lives by using artificial intelligence to reimagine traffic control.

2

Funding Rounds

$50.0k

Money raised

HEBI Robotics’ focuses includes robotics, hardware, and software, with a core focus on motion control.

Industries:

Location:

Key people:

1

Funding Rounds

Fitt is a Pittsburgh-based company founded in 2017.

Industries:

Location:

2

Funding Rounds

$596.0k

Money raised

Simcoach Games develops 3D games and simulation products for workplace safety and product operations training programs.

Sign up to access our full database

Enter your email and get access to 71,000 + technology companies you can partner with.

Join 29000+ founders, operators, and investors.