69 Best Startups in Lyon to Watch in 2025

All-in-one treasury management platform.

Total Raised: $166.52M

Last Funding: $47.50M (Series C)

Vonafexor drug maker for the treatment of Alport syndrome.

Total Raised: $110.47M

Last Funding: $42.57M (Series C)

AI-powered customer service platform.

Total Raised: $16.20M

Last Funding: $16.20M (Series A)

Brenus Pharma is a cancer vaccine developer founded in 2021 by Benoit Pinteur.

Total Raised: $29.50M

Last Funding: $25.00M (Series A)

Animal-free dairy protein.

Total Raised: $20.15M

Last Funding: $4.20M (Seed)

Peptides for the treatment of rare endocrine and related diseases.

Total Raised: $138.63M

Last Funding: $138.63M (Series C)

MRI plug-and-play solution developer for veterinary use.

Total Raised: $5.46M

Last Funding: $5.46M (Series A)

Expense management pltatform.

Total Raised: $25.52M

Last Funding: $25.52M (Series B)

LabLabee is a hands-on training platform for telco cloud providers founded in 2021 by Samir Tahraoui.

Total Raised: $3.40M

Last Funding: $3.40M (Seed)

Energy management SaaS platform.

Total Raised: $3.60M

Last Funding: $3.60M (Series A)

AI-powered accounting automation platform.

Total Raised: $98.55M

Last Funding: $1.00M (Seed)

Accountant service for businesses.

Total Raised: $27.18M

Last Funding: $27.18M (Series A)

Biotechnology company developing advanced cancer treatments.

Total Raised: $34.92M

Last Funding: $30.14M (Series A)

Tumor immunity reserch.

Total Raised: $4.73M

Last Funding: $4.73M (Seed)

Smartphone-powered laptops.

Total Raised: $2.64M

Last Funding: $2.64M (Seed)

Collaborative data governance solutions.

Total Raised: $10.00M

Last Funding: $10.00M (Seed)

Platform that streamlines and automates vulnerability management in cybersecurity.

Total Raised: $15.68M

Last Funding: $13.18M (Series A)

Platform for co-owning second homes with family members or other people.

Total Raised: $16.79M

Last Funding: $14.73M (Seed)

Specialist health insurance for pets.

Total Raised: $169.64M

Last Funding: $169.64M (Unknown)

Platform to treat moderate to severe dysbiosis in patients.

Total Raised: $42.23M

Last Funding: $10.50M (Seed)

Generative art platform.

Total Raised: $5.00M

Last Funding: $5.00M (Seed)

Platform for integrating and optimizing various modes of transportation into a seamless mobility experience.

Total Raised: $1.51M

Last Funding: $1.51M (Seed)

Insect producer for animal feed.

Total Raised: $14.63M

Last Funding: $14.63M (Series A)

Carbon credit marketplace.

Total Raised: $1.61M

Last Funding: $1.61M (Seed)

Multi-channel comms messenger.

Total Raised: $1.60M

Last Funding: $1.60M (Seed)

Platform for horticulture LED lighting systems, photobiology research, and indoor and greenhouse lighting.

Total Raised: $21.60M

Last Funding: $18.62M (Series A)

Tissue regeneration platform based on growth factors.

Total Raised: $19.86M

Last Funding: $12.90M (Series A)

Digital investment platform.

Total Raised: $14.51M

Last Funding: $6.85M (Series A)

3D bioprinting technology for regenerative medicine.

Total Raised: $6.34M

Last Funding: $6.34M (Unknown)

Platform offering assistance to patients and their families to enhance abilities, autonomy, and quality of life.

Total Raised: $4.30M

Last Funding: $4.30M (Seed)

Cutting-edge navigation solutions developer for robotic spinal surgery.

Total Raised: $10.70M

Last Funding: $10.70M (Series A)

Developer of therapeutic molecules to treat cancer.

Total Raised: $8.24M

Last Funding: $8.24M (Series A)

Electric toothbrush with sonic vibration for effective cleaning.

Total Raised: $6.21M

Last Funding: $6.21M (Unknown)

Platform that monitors company solvency by providing legal information.

Total Raised: $13.90M

Last Funding: $13.90M (Unknown)

Carbon emissions and life cycle assessments (LCA) platform for construction projects.

Total Raised: $5.61M

Last Funding: $4.89M (Series A)

Mobile gaming studio.

Total Raised: $7.87M

Last Funding: $6.47M (Series A)

Mon Bel Appart is a French real estate company that provides property management and consultancy services.

Total Raised: $7.86M

Last Funding: $7.13M (Unknown)

SaaS solution using artificial intelligence for HR recommendations.

Total Raised: $12.00M

Last Funding: $12.00M (Series A)

Platform delivering intelligent thermal clothing solutions.

Total Raised: $5.88M

Last Funding: $3.15M (Unknown)

AI-assisted vehicle scanners.

Total Raised: $11.32M

Last Funding: $11.32M (Series A)

Platform for financial departments to prevent transfer fraud.

Total Raised: $6.07M

Last Funding: $6.07M (Series A)

Platform offering security, digital tools, confidentiality, regulatory compliance, KYC, and collaboration services for businesses and banks.

Total Raised: $1.59M

Last Funding: $1.59M (Unknown)

Their policy is geared towards quality and customer satisfaction

Total Raised: $5.66M

Last Funding: $5.66M (Unknown)

Specialist providing electric and unlimited mobility solutions.

Total Raised: $3.65M

Last Funding: $3.65M (Seed)

Educational hub specializing in revealing talent and developing skills through three higher education schools focused on the video game industry.

Total Raised: $7.07M

Last Funding: $7.07M (Unknown)

Marketplace for physical and online multi-services shops.

Total Raised: $3.98M

Last Funding: $3.98M (Series A)

Time and budget AI bot that help teams to work together

Total Raised: $0.96M

Last Funding: $0.96M (Pre Seed)

A unique API connected to the best AI engines and combined with a powerful management platform

Total Raised: $1.65M

Last Funding: $1.65M (Unknown)

Platform for intranasal vaccine candidates preventing pneumovirus infections.

Total Raised: $1.32M

Last Funding: $1.32M (Seed)

Medical device for caregivers allowing efficient toothbrushing in 10 seconds in establishments or at home.

Total Raised: $1.70M

Last Funding: $1.70M (Seed)

Access visual health directly where you live and work !

Total Raised: $8.98M

Last Funding: $8.98M (Series B)

Digital Asset Management, Image Optimisation and CDN Delivery, Web Acceleration

Total Raised: $3.23M

Last Funding: $3.01M (Seed)

Agency specializing in custom Python web application development.

Total Raised: $3.19M

Last Funding: $2.23M (Unknown)

Exorde is the Web 3.0 network that empowers developers to scrape and link all public data on the web.

Total Raised: $1.20M

Last Funding: $0.00M (Unknown)

Accounting services firm offering audit and consulting solutions.

Total Raised: $5.65M

Last Funding: $5.65M (Unknown)

Cybersecurity SaaS dedicated to CISO

Total Raised: $2.75M

Last Funding: $2.75M (Unknown)

Digital platform for managing construction and industrial site waste.

Total Raised: $2.18M

Last Funding: $2.18M (Unknown)

SaaS solution for textile and promotional items that simplifies the production and management of graphic operations.

Total Raised: $1.14M

Last Funding: $1.14M (Seed)

Tool for industrializing and marketing ecological solutions in natural resources.

Total Raised: $2.01M

Last Funding: $2.01M (Seed)

Platform for improving procurement team performance through agile management.

Total Raised: $3.80M

Last Funding: $3.80M (Series A)

Health tech company using clinical trial simulation technology to predict drug efficacy and optimize clinical trial development.

Total Raised: $3.02M

Last Funding: $3.02M (Series A)

Platform for proactive fertility management to expand family-building potential.

Total Raised: $4.53M

Last Funding: $4.53M (Unknown)

Platform for booking holidays tailored for people with special needs.

Total Raised: $1.65M

Last Funding: $1.65M (Series A)

Platform connecting project leaders and franchises with ideal brands.

Total Raised: $1.76M

Last Funding: $1.76M (Unknown)

Catering professional network offering career opportunities, media, and resources for employees.

Total Raised: $1.43M

Last Funding: $1.43M (Unknown)

Software that helps manage and control catering businesses.

Total Raised: $1.13M

Last Funding: $1.13M (Unknown)

AI-driven drug discovery platform.

Total Raised: $1.08M

Last Funding: $1.08M (Pre Seed)

Start-up from France focusing on developing new treatments for diseases.

Total Raised: $1.51M

Last Funding: $1.51M (Series A)

AI to detect patients complication risks.

Total Raised: $2.25M

Last Funding: $2.25M (Seed)