69 Best Cryptocurrency Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of Cryptocurrency Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 622 start-ups with an aggregate funding of $13.7b. The average funding per company in this subset is $198.8m.

Last update to the database: Feb 18, 2025. See changelog.

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4

Funding Rounds

$910.0m

Money raised

An end-to-end blockchain and NFT solution for video games.

1

Funding Rounds

CEX.IO is a cryptocurrency exchange platform that supports a range of cryptocurrencies and has different deposit and withdrawal methods that its traders can utilize for buying or selling digital assets through the usage of FIAT currency.

1

Funding Rounds

$9.0m

Money raised

Tendermint is now Ignite. Tendermint was the core contributor to the Cosmos blockchain network.

Key people:

6

Funding Rounds

$142.5m

Money raised

The first and most experienced company in bitcoin payments, BitPay builds powerful tools for spending, accepting, and building with bitcoin. The company has offices in North America, Europe, and South America and has raised over $70 million from top investors including Index Ventures, Aquiline Technology Growth, Menlo Ventures, Founders Fund, and S

3

Funding Rounds

$17.5m

Money raised

Numerai is a hedge fund with stock market trades determined by crowdsourced artificial intelligence models. The best models receive rewards in the form of a cryptographic token called Numeraire (NMR) on the Ethereum blockchain.

2

Funding Rounds

$27.0m

Money raised

CryptoKitties is a game built on the Ethereum blockchain in which users can collect and trade virtual kittens.

2

Funding Rounds

$7.9m

Money raised

t3rn is a hosting platform for smart contracts, that enables trustless, interoperable, multi-chain execution and composable collaboration.

5

Funding Rounds

$126.5m

Money raised

Celo is an open platform that offers financial tools to mobile phone users.

Location:

Key people:

3

Funding Rounds

$119.2m

Money raised

Phantom is a cryptocurrency wallet by Solana to manage digital assets and access decentralized applications.

1

Funding Rounds

$5.0m

Money raised

Jupiter Exchange is a swap aggregator on Solana.

1

Funding Rounds

$5.0m

Money raised

Colexion is one of Asia’s largest licensed NFT marketplace, allowing digital artists to enter the NFT space and channelise their passion for art and creativity.

8

Funding Rounds

$1.2b

Money raised

CoinDCX is a blockchain company founded in 2017 by Sumit Gupta. CoinDCX is India’s largest and safest cryptocurrency exchange.

Location:

Key people:

7

Funding Rounds

$165.1m

Money raised

Figment is a blockchain infrastructure and software provider.

Location:

Key people:

3

Funding Rounds

$54.2m

Money raised

Layer1 is a cryptocurrency investment and infrastructure platform.

2

Funding Rounds

$24.0m

Money raised

Ondo Finance is an open, permissionless, decentralized investment bank

2

Funding Rounds

$336.0m

Money raised

Mysten Labs creates foundational infrastructure to accelerate the adoption of Web3.

Location:

Key people:

3

Funding Rounds

$764.7m

Money raised

Bitmain is a Beijing-based multinational semiconductor company, founded in 2013, that manufactures products for blockchain and artificial intelligence (AI) applications.

3

Funding Rounds

$2.3m

Money raised

A web and API platform that provides Bitcoin and Altcoin conversion.

1

Funding Rounds

$8.5m

Money raised

Zeta Markets is the premier derivatives protocol on Solana.

9

Funding Rounds

$1.1b

Money raised

Circle is a peer-to-peer payments technology company that is headquartered in Boston, Massachusetts and was founded in 2013 by Jeremy Allaire and Sean Neville.

Location:

Key people:

1

Funding Rounds

$6.0m

Money raised

Maximum protection and yield, fully protected through Protocol Controlled Underwriting.

1

Funding Rounds

$2.4m

Money raised

Cake is an all-in-one decentralized finance (DeFi) platform.

Key people:

6

Funding Rounds

$898.4m

Money raised

Wise, previously TransferWise, is a company that offers money transfers services founded by Kristo Käärmann and Taavet Hinrikus.

2

Funding Rounds

$8.5m

Money raised

DeHorizon is committed to becoming the next generation of Metaverse Game Ecosystem, where players can immersively create, socialize, entertain with other peer players.

3

Funding Rounds

$15.4m

Money raised

SynFutures is a decentralized Derivatives Protocol.

BTC-Alpha is a cryptocurrency exchange platform.

1

Funding Rounds

$9.0m

Money raised

Primitive - Crypto derivative products built on the Replicating Market Maker protocol, an oracle-free solution to scalable and efficient on-chain derivatives.

Key people:

1

Funding Rounds

$8.0m

Money raised

Regulated crypto exchange. Built the world's first regulated tokenised assets platform. It aims to revolutionise cryptocurrency investment.

Key people:

1

Funding Rounds

$5.0m

Money raised

Vertalo is a digital transfer agent that connects and enables a digital asset ecosystem, offering primary capital formation, on-chain share registry, and access to secondary liquidity.

Key people:

9

Funding Rounds

$378.4m

Money raised

Bitso is a cryptocurrency exchange for buying and selling Bitcoin, Ethereum, Litecoin, Bitcoin Cash, TrueUSD, Decentraland, Golem, and Basic Attention Token.

22

Funding Rounds

$1.4b

Money raised

BlockFi is a blockchain platform for high-interest crypto accounts and low-cost credit products.

Key people:

2

Funding Rounds

$14.5m

Money raised

Spice AI is a Seattle-based start-up company building a developer-first platform to create artificial intelligence/machine learning-driven applications that harness time series data.

Location:

Key people:

2

Funding Rounds

$8.0m

Money raised

Mavia is a multiplayer allotment-based strategy game that allows players to build, develop their army, and own property using in-game resources and the RUBY cryptocurrency.

1

Funding Rounds

$17.2m

Money raised

ArDrive is a blockchain-based storage App.

1

Funding Rounds

$50.0m

Money raised

VALR is a company founded in 2018 by Farzam Ehsani, theo bohnen and badi sudhakaran.

1

Funding Rounds

$2.1m

Money raised

Cypher is a decentralized synthetic asset protocol.

4

Funding Rounds

$4.5m

Money raised

Brave is an open source web browser founded in 2015 by Brendan Eich.

Key people:

13

Funding Rounds

$655.6m

Money raised

Chainalysis is a company that provides tools for cryptocurrency analysis, compliance, and investigation.

4

Funding Rounds

$217.0m

Money raised

Aztec is an open source layer 2 network.

Location:

Key people:

1

Funding Rounds

$200.0k

Money raised

Foundation is a blockchain company in which one can create, explore, and collect digital art with non-fungible tokens (NFTs)

2

Funding Rounds

$750.0k

Money raised

PraSaga is building the next-generation layer-1 blockchain

Location:

Zug

Key people:

5

Funding Rounds

$75.9m

Money raised

Unstoppable Domains is a company that offers alt-route domain names based on blockchain technology.

4

Funding Rounds

$23.3m

Money raised

Bitski is a company making a dApp wallet SDK for decentralized applications.

Key people:

1

Funding Rounds

$10.0m

Money raised

A company offering a full-service digital asset management platform with its own stablecoin cryptocurrency pegged to US treasury bonds called the Arca UST Coin.

6

Funding Rounds

$9.8m

Money raised

Facial recognition company Kairos today announced the alpha release of the Kairos Protocol, a biometric verification system for cryptocurrency transactions.

9

Funding Rounds

$136.0m

Money raised

Abra offers a cryptocurrency trading application created to streamline online cryptocurrency transfers and investments.

4

Funding Rounds

$1.4b

Money raised

Nydig is a provider of bitcoin infrastructure and institutional financial services.

Key people:

3

Funding Rounds

$105.0m

Money raised

Talos Trading is a developer of institutional-grade technology infrastructure for digital assets trading and support for the full lifecycle of that trading, including price discovery, execution, and settlement.

Key people:

1

Funding Rounds

$14.0m

Money raised

Buys and sells crypto. Fiat deposits and withdrawals in AUD, EUR, GBP, and USD. Via its crypto exchange, it allows trade, and users keep more of the profits. A feature-rich trading platform built to scale. Margin trading and multiple collateral options including fiat & crypto.

1

Funding Rounds

$8.0m

Money raised

Uphold (formerly Bitreserve) is a cloud-based digital money platform. Users can buy, hold, convert and transact across currencies and commodities, including cryptocurrencies.

2

Funding Rounds

$9.0m

Money raised

Ignite is a blockchain based development group working on projects such as Cosmos and Tendermint Core.

Key people:

1

Funding Rounds

$4.5m

Money raised

Staked helps investors compound their cryptocurrency investments by participating in staking or lending.

Key people:

3

Funding Rounds

$5.8m

Money raised

Parity is a digital wallet for the Ethereum blockchain

4

Funding Rounds

$59.5m

Money raised

Calaxy Inc., is a US company developing the Calaxy app, an open social marketplace for creators.

1

Funding Rounds

Onai is a San Jose, California-based developer of blockchain and machine intelligence technologies.

2

Funding Rounds

$1.0b

Money raised

Ibotta is a free-to-use mobile coupon and cash-back shopping app based in Denver.

Location:

Key people:

6

Funding Rounds

$61.0m

Money raised

Messari is a cryptocurrency data and analytics firm. It's mission is to promote transparency and smarter decision-making in the cryptoasset community. Their open-source data library helps researchers, investors, and regulators make sense of the industry.

1

Funding Rounds

$1.6m

Money raised

Crypto hedgehog is a San Jose, CA-based investment management software company providing a portfolio management app for cryptocurrencies.

Location:

Key people:

1

Funding Rounds

$3.6m

Money raised

A decentralized capital market powered by a cross-margin cross-collateralization clearing engine protocol.

4

Funding Rounds

$148.5m

Money raised

InfStones is a blockchain staking and infrastructure platform that aims to make Web3 ecosystems more accessible.

Location:

Key people:

3

Funding Rounds

$60.0m

Money raised

Zora Labs is a marketplace for non-fungible tokens.

1

Funding Rounds

$9.0m

Money raised

Fluence is a decentralized database project and open data market for decentralized applications.

Key people:

5

Funding Rounds

$1.0b

Money raised

Fireblocks is a New York-based enterprise and computer software company.

Key people:

3

Funding Rounds

$8.6m

Money raised

Nebula Genomics is a genetics company developing a platform for individuals to get their personal genome sequenced, and then enable them to store and control that information through cryptographic encryption on the blockchain.

3

Funding Rounds

$104.0m

Money raised

Hex Trust is a fully-licensed and insured provider of bank-grade custody for digital assets.

Key people:

5

Funding Rounds

$487.0m

Money raised

Anchorage Digital is a global regulated crypto platform that provides institutions with integrated digital asset financial services and infrastructure solutions.

6

Funding Rounds

$211.9m

Money raised

Keyfactor is a software company that provides cloud-first PKI as a service and crypto-agility solutions.

3

Funding Rounds

OpenZeppelin provides security products to build, automate, and operate decentralized applications.

3

Funding Rounds

$16.5m

Money raised

Evernym is a software company that develops an open source sovereign identity block chain.

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