69 Best Startups in Irvine California to Watch in 2025

The Definitive Seedtable Ranking of Startups in Irvine California

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 205 start-ups with an aggregate funding of $8.7b. The average funding per company in this subset is $125.9m.

Last update to the database: Feb 18, 2025. See changelog.

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4

Funding Rounds

$49.0m

Money raised

Siklu is a San Jose, California and Petah Tikva-based telecommunications company developing multi-gigabit wireless fiber connectivity systems for urban, suburban, and rural areas.

7

Funding Rounds

$2.2b

Money raised

Anduril builds AI platforms to protect troops, fight wildfires, perform search & rescue missions, and provide border surveillance. It was founded in 2017 and is located in Irvine, California.

2

Funding Rounds

$2.0b

Money raised

Razer is a United States-based company founded in 2005 by Min-Liang Tan.

6

Funding Rounds

$317.0m

Money raised

BigPanda offers a platform that helps IT Ops, NOC, and DevOps teams detect, investigate, and resolve IT incidents.

12

Funding Rounds

$507.3m

Money raised

Acorns is an Irvine, California-based micro-investing company allowing users to round up consumer purchases and invest the change.

4

Funding Rounds

$163.9m

Money raised

Celestial AI is a machine learning (ML) accelerator company developing the Photonic Fabric platform, an optical interconnect technology for memory and compute.

7

Funding Rounds

$151.6m

Money raised

A carbon sequestration technology and bioplastics company based in Huntington Beach, California, founded in 2003, that uses their technology to capture carbon from greenhouse emissions for production of bioplastics.

1

Funding Rounds

$4.0m

Money raised

CYBAVO is a company founded by experts in computer security and blockchain industry.

1

Funding Rounds

$16.0m

Money raised

Oculus VR is an american virtual reality technology company founded in 2012 by Jack McCauley, Palmer Luckey, Brendan Iribe, Michael Antonov and Nate Mitchell.

2

Funding Rounds

$62.8m

Money raised

Movandi is an American venture backed startup company, founded by Maryam Reza and Rofougaran based in Newport Beach, California.

2

Funding Rounds

$18.0m

Money raised

SecureAuth is an Irvine, California-based provider of access control solutions for premises, cloud and web applications, and resources. Solutions include multi-factor authentication, single sign-on, adaptive authentication, and self-service tools. The company provides both cloud-based and virtual appliances.

1

Funding Rounds

$9.0m

Money raised

Immerse is an Irvine, California-based virtual reality company offering tools and technology for education and language learning using virtual reality.

1

Funding Rounds

$10.0m

Money raised

Liquipel is a manufacturer of nanotechnology products that claims to provide super-hydrophobic protection and corrosion resistance to a variety of products, including smartphones, ear buds and headphones, tablets and other mobile electronics.

2

Funding Rounds

$1.4m

Money raised

A company offering a still image and video analytics platform using computer vision.

4

Funding Rounds

$120.1m

Money raised

Syntiant is an Irvine, California-based company founded in 2017 by Pieter Vorenkamp, Kurt Busch, Jeremy Holleman and Steph Bailey.

7

Funding Rounds

$198.4m

Money raised

Mavenlink is a company founded in 2008.

6

Funding Rounds

$121.6m

Money raised

Enevate Corporation is a developer of energy storage technology for lithium-ion battery ecosystems.

3

Funding Rounds

$5.6m

Money raised

A company making digital asset management and marketing operations software.

5

Funding Rounds

$44.5m

Money raised

Kareo is a medical billing services company providing a web-based medical practice management software.

4

Funding Rounds

$256.7m

Money raised

Menlo Micro has created an entirely new category of electronic switches with its Ideal Switch technology. Menlo is bringing more than 99 percent reductions in size, weight, power, and cost to dozens of industries such as medical, aerospace and defense, telecommunications, consumer electronics, industrial IoT, and test and measurement.

6

Funding Rounds

$11.2m

Money raised

Youmail is an Irvine, California-based company founded in 2007 by Ken Brickley.

8

Funding Rounds

$180.0m

Money raised

Agendia is an Irvine, California-based molecular diagnostics company.

1

Funding Rounds

$20.0m

Money raised

Restaurant365 is a foodservice supply chain and procurement management software company.

3

Funding Rounds

$75.8m

Money raised

Specright developed the Specification Data Management platform to manage and map product and packaging data across the supply chain.

1

Funding Rounds

$500.0k

Money raised

CELESTIAL THERAPEUTICS INC. is an Irvine, California-based company founded in 2019.

Location:

3

Funding Rounds

$37.0m

Money raised

WebVisible is an Irvine, California-based company founded in 2001.

2

Funding Rounds

$120.0m

Money raised

Bionic Pancreas

2

Funding Rounds

$5.4m

Money raised

Levyx provies an enterprise-class data management platform for a variety of big data applications.

4

Funding Rounds

$38.7m

Money raised

NGD Systems is a company developing data storage and computation products.

1

Funding Rounds

$3.5m

Money raised

Legalmation provies an AI-powered analytics solution which helps automate routine litigation processes.

1

Funding Rounds

$16.0m

Money raised

Drybar is an establishments serving non-alcoholic refreshments founded in 2010.

Industries:

2

Funding Rounds

$550.0m

Money raised

Kajabi is an Irvine, California-based company founded in 2010.

4

Funding Rounds

$26.6m

Money raised

BlueCava is an Irvine, California-based online advertising company using device identification services to reach across networks and technologies for advertising services.

1

Funding Rounds

Docbot is a software company designing and building a software for physicians to automate patient intake, screen questionnaires and generate clinical notes.

2

Funding Rounds

$16.6m

Money raised

Netlist, Inc is an Irvine, California-based semiconductor company founded in 2000.

Industries:

Location:

1

Funding Rounds

$75.0m

Money raised

Performio is a company founded in 2006 by David Marshall.

3

Funding Rounds

$35.0m

Money raised

Zadara provide complete data backup and protection delivered as a fully-managed service.

1

Funding Rounds

$1.0m

Money raised

Pivotshare is an Irvine, California-based company founded in 2010.

5

Funding Rounds

$90.5m

Money raised

Cloudvirga is a mortgage lending technology company founded in 2016 by Bill Dallas, Kyle Kamrooz and Mark Attaway.

3

Funding Rounds

$75.0m

Money raised

Greenwave's AXON Platform enables IoT and M2M network service providers to address security, interoperability, flexibility and scalability from a single IoT platform.

3

Funding Rounds

$20.6m

Money raised

Zuum is an Irvine, California-based logistics company focusing on managing freight through AI technology.

Industries:

Location:

Key people:

4

Funding Rounds

$128.0m

Money raised

iTrustCapital is a company founded by Todd Southwick.

3

Funding Rounds

$5.5m

Money raised

2C Tech Corporation, Inc. is a nanoparticles for Ophthalmology founded by Naresh Mandava.

2

Funding Rounds

$59.9m

Money raised

Lumitron Technologies develops and commercializes new high­‐fidelity imaging x-ray systems.

2

Funding Rounds

$135.0m

Money raised

JenaValve Technology is a transcatheter aortic valve replacement system founded in 2006.

3

Funding Rounds

$29.5m

Money raised

Aivita Biomedical is a stem Cell Therapy founded in 2016.

1

Funding Rounds

$5.0m

Money raised

Apptricity Corporation is a company founded in 1999.

3

Funding Rounds

$12.0m

Money raised

Cyvatar is a technology-enabled cyber security as a service (CSaaS) provider disrupting a $150 billion industry by introducing and delivering smarter, measurable managed security subscriptions to help you achieve compliance and security faster and more efficiently.

Industries:

Location:

1

Funding Rounds

$2.0m

Money raised

Turion Space is an Irvine, California-based company developing a Droids spacecraft designed to deorbit space debris and provide inspection and relocation services.

Key people:

1

Funding Rounds

$4.1m

Money raised

Solar Monkey installs PV systems for commercial and industrial users.

1

Funding Rounds

$91.7m

Money raised

Auction.com is an Irvine, California-based company founded in 2007.

1

Funding Rounds

$3.0m

Money raised

Prodoscore is an Irvine, California-based company founded in 2018 by Denise Hazime.

1

Funding Rounds

$8.0m

Money raised

Guardtime's Black Lantern platform provides real-time cybersecurity and data-centric asset protection.

2

Funding Rounds

$52.0m

Money raised

Ivantis is an Irvine, California-based company.

Location:

1

Funding Rounds

$1.0m

Money raised

Oomba is an Irvine, California-based company founded in 2012 by Nolan Bushnell, Michael Johnson, Michael Williams, Dylan Hundley, William Farah and Paul Kim.

1

Funding Rounds

$16.0m

Money raised

Caylent is an Irvine, California-based company founded in 2015 by Stefan Thorpe.

2

Funding Rounds

$370.0k

Money raised

SRCH2 is an Irvine, California-based company founded in 2010 by Chen Li.

1

Funding Rounds

$4.7m

Money raised

CG Oncology is an Irvine, California-based company.

1

Funding Rounds

$2.0m

Money raised

Givsum is a company founded in 2013 by Alan McCann, Shawn Wehan, Robert Kollar, Dewey Bushaw, Mat Masoni and Ralf Krestel.

7

Funding Rounds

$74.9m

Money raised

Combimatrix Molecular Diagnostics, Inc. is a company that is part of the Medical & Diagnostic Laboratories Industry.

1

Funding Rounds

$14.0m

Money raised

Carro is the largest collaborative commerce platform and cross-store sales channel connecting Shopify to all of eCommerce.

Location:

Key people:

1

Funding Rounds

$91.7m

Money raised

Ten-X provides an online real estate marketplace allowing people to buy and sell real estate properties.

4

Funding Rounds

$101.1m

Money raised

HighLife SAS is a Paris-based company founded in 2010.

1

Funding Rounds

$8.0m

Money raised

Ivideon is a company founded in 2010.

1

Funding Rounds

$1.6m

Money raised

A molecular diagnostics company focused on women's gynecologic cancers

2

Funding Rounds

Raise3D, Inc. is a company that offers 3D printer from rapid-prototyping to manufacturing.

1

Funding Rounds

$22.0m

Money raised

Cold Genesys is a privately-held, immunotherapy based biopharmaceutical company

2

Funding Rounds

$7.0m

Money raised

Sendio is an Irvine, California-based company founded in 2003.

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