27 Best Startups in Rome to Watch in 2025

C3 AI is an enterprise artificial intelligence software company providing a family of integrated products for accelerating digital transformation.

Altiostar Networks is a company that provides 4G and 5G open vRAN software in a B2B model.

Hootsuite is a social network management platform created to interact, listen and analyze results.

Keyless is a privacy-preserving biometric authentication solutions provider founded in 2019 by Andrea Carmignani, Rolf Hoefer, Giuseppe Ateniese and Fabian Eberle.

Italian blockchain company focused on disaster insurance and charity.

Memopal is a cloud-based storage application and service that enables users to store and synchronize computer files and share files and folders with others using the Internet.

Clinical Research & Services

SeeQC is a company developing and commercializing quantum technologies founded in 2019.

Developer of a genomic risk prediction platform designed to democratize access to clinical-grade polygenic risk scores (PSRs). The company combines datasets with advanced algorithms to build PRSs with high predictive power for estimating disease risk and translating the potential of genomic data into practical tools.

Exein are on a mission to build the world's first ecosystem for firmware security so that all different types of firmware are secure around the world.

Operator of a cybersecurity platform intended to provide cyber defense services for IT and OT infrastructures. The company's platform provides a technology that features include endpoint detection and response, network security appliance, risk management, module management.

Platform that helps doctors quickly diagnose and treat rare genetic diseases within 24 hours using AI.

TaTaTu is a social entertainment platform that rewards users when they watch and share photos and videos.

Insoore is a platform that helps insurance companies to improve the claims management process, thanks to on-demand photographic inspections and damage estimates provided by a community of experts.

Mobile app that transforms punching bags into smart devices for detecting, measuring, and reacting to strikes.

MioAssicuratore is an online insurance broker that helps customers in the harmful world of insurance.

Platform providing football video and data analytics services.

Nextwin is a Rome-based company founded in 2014.

Bulsara Advertising is a media agency offering communication and advertising services founded in 2011 by Roberto Marazzini.

Training and education platform for schools, young professionals and workers.

Radical Storage is a luggage storage platform founded in 2016 by Alessandro Seina .

Switch is an AI-powered fleet management platform founded by Matteo Forte.

Filo is a Rome-based company founded in 2014.

Instruments utilizing optical and electrooptical technology for scientific and industrial applications.

Suprema is a producer of superconductive tapes founded in 2024 by Fabio Fabbri , Andrea Augieri and Francesco Rizzo .

Allelica, Inc. is a Rome-based company.

CM Sistemi is a company founded in 1983.