36 Best Startups in Portland Maine to Watch in 2025

The Definitive Seedtable Ranking of Startups in Portland Maine

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 36 start-ups with an aggregate funding of $805.1m. The average funding per company in this subset is $22.4m.

Last update to the database: Feb 18, 2025. See changelog.

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7

Funding Rounds

$16.1m

Money raised

We built Defendify to help small businesses navigate the cybersecurity landscape with cybersecurity that is dead simple, affordable, and works around the clock.

2

Funding Rounds

$52.0m

Money raised

Chrome River Technologies is a global provider of expense reporting and invoice management.

1

Funding Rounds

LibraryThing is a social cataloging web application founded in 2005 by Tim Spalding.

1

Funding Rounds

$10.0m

Money raised

Ocean Renewable Power Company is a company founded in 2004.

1

Funding Rounds

$1.9m

Money raised

Certify is a Portland, Maine-based company founded in 2008.

1

Funding Rounds

$20.0m

Money raised

Digital Owl is a company founded by Amit Man.

3

Funding Rounds

$4.8m

Money raised

HighByte, Inc. is a Portland, Maine-based company founded in 2018 by Tony Paine.

Location:

1

Funding Rounds

$1.0m

Money raised

Our peer engagement platform helps higher ed improve enrollment and the learning experience. Nearpeer is the best way for incoming and current students to find and engage with peers “like them” - creating community, sense of belonging, and higher commitment to their college.

Location:

Key people:

2

Funding Rounds

$10.3m

Money raised

Rockstep Solutions is a company founded in 2013.

21

Funding Rounds

$30.6m

Money raised

Coastal Realty Capital, LLC is a Portland, Maine-based company.

Location:

3

Funding Rounds

$4.7m

Money raised

Platform providing team communication and engagement for deskless workers.

Location:

1

Funding Rounds

$5.0m

Money raised

Tilson is a Portland, Maine-based company founded in 1996.

1

Funding Rounds

$1.0m

Money raised

ALM Ortho design and development of orthopedic implants and products for ortho surgerns.

1

Funding Rounds

$223.0m

Money raised

Vets First Choice is a Portland, Maine-based company.

1

Funding Rounds

RxAnte is a Portland, Maine-based company.

2

Funding Rounds

$1.7m

Money raised

Mobile Price Card Inc. is a retail company founded in 2015.

Industries:

1

Funding Rounds

$2.0m

Money raised

Building technology to fight recidivism, incarceration, and addiction.

1

Funding Rounds

$3.5m

Money raised

Myhealthmath is a Portland, Maine-based company founded in 2014.

2

Funding Rounds

$30.0m

Money raised

MedRhythms is a Portland, Maine-based company.

2

Funding Rounds

$3.4m

Money raised

Kinotek LLC is a Portland, Maine-based company founded in 2018.

Location:

2

Funding Rounds

$10.9m

Money raised

Vetro, Inc. is a Portland, Maine-based company founded in 2020.

Location:

1

Funding Rounds

$5.0m

Money raised

Tilson Technology Management is a Portland, Maine-based company founded in 1996.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Cultivation, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Retail #1, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$7.1m

Money raised

West Bayside Partners, LLC is a Portland, Maine-based company founded in 2013.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Manufacturing, LLC is a Portland, Maine-based company founded in 2019.

Location:

2

Funding Rounds

$1.3m

Money raised

Mathematics & Problem Solving LLC is a Portland, Maine-based company founded in 2015.

Location:

1

Funding Rounds

$6.6m

Money raised

NC/SR Sanford Equity LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$5.0m

Money raised

CC-600 Washington, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$100.0m

Money raised

Housing New England, Fund I LP is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$2.3m

Money raised

PF Marina OZ Fund LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$250.0k

Money raised

Ocean Data Network, Inc. is a Portland, Maine-based company.

Location:

1

Funding Rounds

$850.0k

Money raised

River Hill Fund, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$4.0m

Money raised

Forager is a Portland, Maine-based technology company.

Industries:

Location:

1

Funding Rounds

$7.5m

Money raised

Ocean Renewable Power Co is a Portland, Maine-based company.

1

Funding Rounds

$223.0m

Money raised

Vets first Choice is a Portland, Maine-based company.

Location:

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