20 Best Startups in Brookline to Watch in 2025

The Definitive Seedtable Ranking of Startups in Brookline

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 20 start-ups with an aggregate funding of $366.5m. The average funding per company in this subset is $18.3m.

Last update to the database: Aug 5, 2025. See changelog.

Track over 71,000 companies

Discover
Fast-growing Global startups

Seedtable uses technology and people to track over 71,000 companies to help you find the right ones to partner with.

Pricing + Sign up

7

Funding Rounds

$8.4m

Money raised

Pison is a human performance company that optimizes cognitive and physiological capability using gesture control.

Key people:

2

Funding Rounds

$91.5m

Money raised

Design, integrate, and automate document workflows using a single platform.

3

Funding Rounds

$7.8m

Money raised

Medical diagnostics company developing diagnostic tests for fever syndromes and infectious diseases

Key people:

6

Funding Rounds

$42.3m

Money raised

Day Zero Diagnostics is a Allston and Boston-based manufacturer and supplier of molecular diagnostic tools.

Key people:

1

Funding Rounds

$4.5m

Money raised

Panoptic is a perpetual, oracle-free options protocol built on the Ethereum blockchain.

Key people:

1

Funding Rounds

$2.5m

Money raised

C14, INC. is the developer of a payment and Web3 interface for the integration of crypto and fiat world payments.

5

Funding Rounds

$35.1m

Money raised

GRO Biosciences was founded by Dr. George Church at the Harvard Life Lab.

Key people:

3

Funding Rounds

$3.7m

Money raised

Greensight Agronomics is a company founded in 2014 by James Peverill.

Key people:

3

Funding Rounds

$15.3m

Money raised

Rejuvenate Bio is a startup company that manipulates genetic make-up to reverse aging in dogs and human.

3

Funding Rounds

$26.0m

Money raised

XRHealth is a telemedicine startup that uses a VR platform that enables remote treatment. The XRHealth VR/AR telehealth platform is ISO certified, FDA certified and HIPAA compliant.

2

Funding Rounds

$2.1m

Money raised

Surgibox Inc. is a Boston-based transportable healthcare company founded in 2017.

1

Funding Rounds

$8.3m

Money raised

1

Funding Rounds

$825.0k

Money raised

RenalSense is a medical diagnostics company manufacturing detection systems for renal function founded by Avi Kleiman.

1

Funding Rounds

Vie Science, Inc. is a digital health company specializing in fertility and reproductive wellness solutions.

3

Funding Rounds

$28.7m

Money raised

Torus Biosystems, Inc. is a Brookline, Massachusetts-based biotechnology company founded in 2019.

Industries:

2

Funding Rounds

$5.0m

Money raised

TireTutor, Inc. is a Brookline, Massachusetts-based company founded in 2018.

2

Funding Rounds

$2.6m

Money raised

GetTrained, Inc. is a Brookline, Massachusetts-based company founded in 2021.

1

Funding Rounds

$1.0m

Money raised

Crimson BioPharm Inc. is a Brookline, Massachusetts-based company founded in 2018.

1

Funding Rounds

$1.2m

Money raised

Mercury Business Services Holdings, LLC is a Brookline, Massachusetts-based company founded in 2017.

1

Funding Rounds

$79.7m

Money raised

Aviceda Ophthalmics, Inc. is a Brookline, Massachusetts-based company founded in 2019.

Sign up to access our full database

Enter your email and get access to 71,000 + technology companies you can partner with.

Join 29000+ founders, operators, and investors.