69 Best Startups in Waltham Maine to Watch in 2025

The Definitive Seedtable Ranking of Startups in Waltham Maine

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 78 start-ups with an aggregate funding of $1.1b. The average funding per company in this subset is $16.2m.

Last update to the database: Feb 18, 2025. See changelog.

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1

Funding Rounds

$4.0m

Money raised

A pharmaceutical company that uses a zebrafish drug-screening platform to find drug candidate molecules that have the capacity to promote regeneration of tissues. Their drug candidate MSI-1436 is being developed and tested for the treatment of heart disease, Duchenne Muscular Dystrophy and diabetic nephropathy.

3

Funding Rounds

$36.5m

Money raised

Covenant Surgical Partners is a company that operates ambulatory surgery centers founded in 2008.

8

Funding Rounds

$35.9m

Money raised

InSphero is a medical technology manufacturing company.

6

Funding Rounds

$358.2m

Money raised

Dragos has built the first industrial cybersecurity ecosystem, the ultimate security defense.

7

Funding Rounds

$16.1m

Money raised

We built Defendify to help small businesses navigate the cybersecurity landscape with cybersecurity that is dead simple, affordable, and works around the clock.

10

Funding Rounds

$7.8m

Money raised

Cerahelix is a company founded in 2011 by Donald MacKay.

2

Funding Rounds

$52.0m

Money raised

Chrome River Technologies is a global provider of expense reporting and invoice management.

1

Funding Rounds

LibraryThing is a social cataloging web application founded in 2005 by Tim Spalding.

1

Funding Rounds

$10.0m

Money raised

Ocean Renewable Power Company is a company founded in 2004.

1

Funding Rounds

Cobbler Technologies is a company that commercializes 3DAPD, an advanced 3D-printer technology for producing mult-material shoe soles.

1

Funding Rounds

$1.2m

Money raised

pumpspotting is the first-ever social platform and global community for breastfeeding moms. In a world where breastfeeding is vital, yet hard, and only 1 in 5 women make it to the recommendation of a year, we use technology and in-person experiences to make breastfeeding less isolating, more supportive, and more attainable at every stage in the journey. Think Facebook meets Yelp meets boob. pumpspotting is a social app and global community connecting breastfeeding women over milk, motherhood, and the best places to nurse & pump.

3

Funding Rounds

$55.5m

Money raised

Adnexus Therapeutics is a company founded by Noubar Afeyan.

1

Funding Rounds

$50.0k

Money raised

Sun Diagnostics is a New Gloucester, Maine-based diagnostic tools company developing solutions and products for in vitro diagnostics founded in 2012 by John Contois.

3

Funding Rounds

BlueTrace is a Castine, Maine-based company founded in 2017 by Chip Terry, Andy Kearney, Catherine Ganim and Drew Condon.

1

Funding Rounds

$353.0k

Money raised

Intelligent Bio-Systems, Inc. is a DNA sequencing developing company.

1

Funding Rounds

$1.9m

Money raised

Certify is a Portland, Maine-based company founded in 2008.

1

Funding Rounds

$1.1m

Money raised

Hyperlite Mountain Gear is a Biddeford, Maine-based company founded in 2009.

Location:

4

Funding Rounds

$2.1m

Money raised

Bar Harbor BioTechnology, Inc. is a company that offers quality software and consumables for genetic research.

2

Funding Rounds

$33.0m

Money raised

Codon Devices was a privately-held biotechnology company that focused on enabling the commercial applications of synthetic biology.

1

Funding Rounds

$20.0m

Money raised

Digital Owl is a company founded by Amit Man.

2

Funding Rounds

$1.8m

Money raised

EXOCHAIN is a blockchain company founded in 2017 by Bob Stewart.

3

Funding Rounds

$4.8m

Money raised

HighByte, Inc. is a Portland, Maine-based company founded in 2018 by Tony Paine.

Location:

1

Funding Rounds

$1.0m

Money raised

Our peer engagement platform helps higher ed improve enrollment and the learning experience. Nearpeer is the best way for incoming and current students to find and engage with peers “like them” - creating community, sense of belonging, and higher commitment to their college.

Location:

Key people:

1

Funding Rounds

$15.0m

Money raised

Company

1

Funding Rounds

Polar OLED is a company that was created from the University of Hull.

2

Funding Rounds

$10.3m

Money raised

Rockstep Solutions is a company founded in 2013.

1

Funding Rounds

$1.2m

Money raised

CourseStorm is an Orono, Maine-based company founded in 2011.

$930.0k

Money raised

Service for fossil-free office recycling and sorting for companies.

21

Funding Rounds

$30.6m

Money raised

Coastal Realty Capital, LLC is a Portland, Maine-based company.

Location:

3

Funding Rounds

$4.7m

Money raised

Platform providing team communication and engagement for deskless workers.

Location:

1

Funding Rounds

$2.6m

Money raised

Healer, Inc. is a Falmouth, Maine-based company in the cannabis industry founded in 2016.

Industries:

Location:

1

Funding Rounds

$18.0k

Money raised

AccelGolf is a Maine-based company founded in 2008 by James Daniels.

Industries:

Location:

1

Funding Rounds

$3.8m

Money raised

Atlantic Sea Farms is a Food and Beverage company.

1

Funding Rounds

$5.0m

Money raised

Tilson is a Portland, Maine-based company founded in 1996.

1

Funding Rounds

$1.0m

Money raised

ALM Ortho design and development of orthopedic implants and products for ortho surgerns.

1

Funding Rounds

$223.0m

Money raised

Vets First Choice is a Portland, Maine-based company.

2

Funding Rounds

$2.0m

Money raised

pumpspotting, Inc. is a Eliot, Maine-based parenting company founded in 2015.

Industries:

Location:

5

Funding Rounds

$2.4m

Money raised

Orono Spectral Solutions, Inc. is an Hermon, Maine-based company.

Location:

1

Funding Rounds

$5.0m

Money raised

Sera Labs is the premiere CBD brand creating products that are natural and holistic, dedicated to health and wellness.

1

Funding Rounds

RxAnte is a Portland, Maine-based company.

2

Funding Rounds

$1.7m

Money raised

Mobile Price Card Inc. is a retail company founded in 2015.

Industries:

1

Funding Rounds

$2.0m

Money raised

Building technology to fight recidivism, incarceration, and addiction.

1

Funding Rounds

$3.5m

Money raised

Myhealthmath is a Portland, Maine-based company founded in 2014.

2

Funding Rounds

$30.0m

Money raised

MedRhythms is a Portland, Maine-based company.

2

Funding Rounds

$3.4m

Money raised

Kinotek LLC is a Portland, Maine-based company founded in 2018.

Location:

3

Funding Rounds

$4.7m

Money raised

WALLIT, INC. is a Westbrook, Maine-based company founded in 2016.

Location:

2

Funding Rounds

$7.5m

Money raised

FlipMetrics Inc. is a company founded in 2021.

3

Funding Rounds

Bookclubz, Inc. is a Camden, Maine-based company founded in 2019.

Location:

2

Funding Rounds

$10.9m

Money raised

Vetro, Inc. is a Portland, Maine-based company founded in 2020.

Location:

1

Funding Rounds

$5.0m

Money raised

Tilson Technology Management is a Portland, Maine-based company founded in 1996.

Location:

2

Funding Rounds

$7.5m

Money raised

NORTHEAST KIND INC is a Eliot, Maine-based company founded in 2017.

Location:

3

Funding Rounds

$5.0m

Money raised

Research Enhanced Design & Development, Inc. is a Brunswick, Maine-based company founded in 2015.

Location:

1

Funding Rounds

Georgetown Broadband LLC is a Georgetown, Maine-based telecommunications equipment company founded in 2021.

3

Funding Rounds

$3.0m

Money raised

Coursestorm, Inc. is an Orono, Maine-based company.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Cultivation, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$1.6m

Money raised

Springworks Farm is a Lisbon, Maine-based company founded in 2014.

Location:

2

Funding Rounds

$6.6m

Money raised

Ourly.Help, Inc. is a Maine-based company founded in 2016.

Location:

1

Funding Rounds

$1.0

Money raised

Arcanna, LLC is a Eliot, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Retail #1, LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$7.1m

Money raised

West Bayside Partners, LLC is a Portland, Maine-based company founded in 2013.

Location:

1

Funding Rounds

$3.5m

Money raised

Coast 2 Coast Extracts Manufacturing, LLC is a Portland, Maine-based company founded in 2019.

Location:

2

Funding Rounds

$1.3m

Money raised

Mathematics & Problem Solving LLC is a Portland, Maine-based company founded in 2015.

Location:

3

Funding Rounds

Constant Energy Capital Management, Inc. is a Falmouth, Maine-based company.

Location:

1

Funding Rounds

Farmhand Automation, Inc. is a Biddeford, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$1.2m

Money raised

Adopets, Inc. is a South Portland, Maine-based company founded in 2017.

1

Funding Rounds

$40.0m

Money raised

BAR HARBOR BANKSHARES is a Bar Harbor, Maine-based company.

Location:

1

Funding Rounds

$6.6m

Money raised

NC/SR Sanford Equity LLC is a Portland, Maine-based company founded in 2019.

Location:

1

Funding Rounds

$5.0m

Money raised

CC-600 Washington, LLC is a Portland, Maine-based company founded in 2019.

Location:

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