69 Best Startups in Houghton Michigan to Watch in 2025

The Definitive Seedtable Ranking of Startups in Houghton Michigan

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 355 start-ups with an aggregate funding of $30.8b. The average funding per company in this subset is $446.0m.

Last update to the database: Feb 18, 2025. See changelog.

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9

Funding Rounds

$995.5m

Money raised

Luminar Technologies is an Orlando, Florida-based automotive industry company.

2

Funding Rounds

$64.0m

Money raised

Endpoint Health specializes in precision immunology therapeutics for patients with critical and chronic inflammatory illnesses.

3

Funding Rounds

$53.1m

Money raised

Censys is an Ann Arbor, Michigan-based computer and network security company.

1

Funding Rounds

Remora is a carbon capture for semi trucks founded in 2020 by Paul Gross.

4

Funding Rounds

$14.0m

Money raised

A biotechnology company developing and commercializing spider silk for textiles and performance polymers. Kraig Biocraft Laboratories uses genetic engineering to produce recombinant spider silk based fibers on an industrial scale.

11

Funding Rounds

$3.3b

Money raised

An online marketplace to buy & sell verified authentic sneakers, streetwear, handbags, and watches.

2

Funding Rounds

$17.5m

Money raised

Coinshift (Formerly MultiSafe) is simplifying crypto treasury management on top of Gnosis safe

1

Funding Rounds

XanEdu is a publishing company that offers custom course materials.

2

Funding Rounds

$11.0m

Money raised

Quest Software is a division of dell inc.; former company founded in 1987 by Vinny Smith.

2

Funding Rounds

$29.8m

Money raised

Orbion develops and manufactures plasma propulsion systems for small satellites.

2

Funding Rounds

$71.5m

Money raised

Now known as Sierra Oncology, is a clinical stage drug development company in Vancouver that focuses on cancer and hematology treatments.

9

Funding Rounds

$138.9m

Money raised

SkySpecs is a company founded in 2012 by Daniel Ellis.

12

Funding Rounds

$273.6m

Money raised

Vestaron is a Kalamazoo, Michigan-based agricultural technology company manufacturing bioinsecticides from naturally occurring peptides

3

Funding Rounds

$14.8m

Money raised

NationBuilder sells software designed to power organizations, movements, and campaigns.

3

Funding Rounds

$18.0k

Money raised

Ambassador is a company founded by Jeff Epstein.

2

Funding Rounds

$30.0m

Money raised

Algo is a Michigan-based company offering an AI supply chain platform. The company was acquired by Meltwater in August 2017.

1

Funding Rounds

$1.5m

Money raised

Cayman Chemical Company is an Ann Arbor, Michigan-based biotechnology company manufacturing healthcare and research diagnostic tools including assay kits, antibodies, proteins, and biochemicals.

4

Funding Rounds

$59.8m

Money raised

Clinc is a company with an artificial intelligence platform that looks to enable enterprises to create virtual assistants

5

Funding Rounds

$109.0m

Money raised

Upstream Security is an artificial intelligence company founded by Yoav Levy that develops automotive cloud security software.

5

Funding Rounds

$188.5m

Money raised

A company developing autonomous vehicles for central business districts, enterprise campuses and residential communities

4

Funding Rounds

$17.9m

Money raised

A robotic automation company making a robotic systems for changing car tires.

1

Funding Rounds

$20.0m

Money raised

GENOMENON is an Ann Arbor, Michigan-based company founded in 2014.

3

Funding Rounds

$10.3m

Money raised

ArborMetrix is an Ann Arbor, Michigan-based company founded in 2011.

3

Funding Rounds

$3.1m

Money raised

Derq is an MIT spinoff that uses AI to power an award-winning predictive platform, help eliminate crashes and create safer and smarter roads.

1

Funding Rounds

$1.0m

Money raised

Totle is a crypto portfolio manager and trading platform built on top of multiple decentralized exchanges.

4

Funding Rounds

$140.3m

Money raised

StrataOncology is a tumor sequencing for therapeutic targeting founded in 2015 by Dan Rhodes, Dan Rhodes and Scott Tomlins.

3

Funding Rounds

$19.5m

Money raised

Provider of ground station services for satellite communications.

Key people:

5

Funding Rounds

$60.4m

Money raised

Guardhat is a company concentrated in Internet of Things (IoT) safety technology for the global industrial workforce.

5

Funding Rounds

$164.3m

Money raised

ONL Therapeutics (ONL) is a clinical-stage biopharmaceutical company committed to helping patients see the future.

1

Funding Rounds

Olark provides a live chat platform that enables enterprises to talk to customers browsing their website.

1

Funding Rounds

$8.0m

Money raised

Xoran Technologies is an Ann Arbor, Michigan-based company.

1

Funding Rounds

$40.0m

Money raised

Corium International is a transdermal Generics, Consumer Products founded in 1999.

8

Funding Rounds

$34.7m

Money raised

Swift Biosciences is a biotechnology company founded in 2010 by Timothy Harkins.

6

Funding Rounds

$102.5m

Money raised

Autobooks is a Detroit-based developer of an integrated payments and accounting platform.

1

Funding Rounds

$7.3m

Money raised

EeroQ is a New York City-based quantum computing-focused company founded in 2016.

2

Funding Rounds

$100.0k

Money raised

Elegus Technologies is an Ann Arbor, Michigan-based company founded by Long Qian, Siuon Tung, Nicholas Kotov and John Hennessy.

2

Funding Rounds

$23.7b

Money raised

Acrisure is a leading national brokerage with local insurance and benefits agencies and specialties. Our headquarters is in Caledonia, Michigan, MI, with offices in MI, IL, IN, AL, GA, FL, NJ, NY, PA, TX, OK, CT, MO, CA, AZ, NV, LA, AR, MD, VA, KY and MN, . Through our agencies, we offer a broad spectrum of insurance related products, consulting services, and enhanced carrier relationships to their numerous personal and commercial clients. Acrisure is one of the top 15 largest privately held insurance agencies in the nation. We built its strength on the reputation of our local agency offices in combination with the vast resources of Acrisure, to better service our clients and prospects.

7

Funding Rounds

$123.8m

Money raised

A company focused on developing immunotherapy treatments for autoimmune disease and cancer

1

Funding Rounds

$2.0m

Money raised

Droneview Technologies Llc offers aerial data acquisition services to companies.

5

Funding Rounds

$46.5m

Money raised

Karamba Security is an automotive Security & IoT Protection founded in 2016 by Ami Dotan.

1

Funding Rounds

$6.0m

Money raised

Plex Systems is a software company founded in 2017.

2

Funding Rounds

$17.5m

Money raised

Automation software to manage additive manufacturing part selection, ordering and production workflows for Industry 4.0.

3

Funding Rounds

$40.1m

Money raised

Cradle Genomics is a San Diego-based prenatal diagnosis company.

2

Funding Rounds

$750.0k

Money raised

Chalkfly is a Detroit-based company founded in 2012 by Andrew Landau.

1

Funding Rounds

$1.4m

Money raised

Genego provides data for pharmaceutical research.

6

Funding Rounds

$50.2m

Money raised

Sakti3 is a company that operates as a leader in the solid state battery technology.

3

Funding Rounds

$49.4m

Money raised

Delphinus is a company developing, comercializing, and servicing breast cancer screening solutions to hospitals and imaging centers.

1

Funding Rounds

Altimetrik is a Southfields-based company founded in 2012.

7

Funding Rounds

$20.3m

Money raised

XG Sciences develops and produces multifunctional materials that are based on their xGnP brand graphene nano-platelets. The company manufactures these nano-platelets through proprietary techniques that allow them to control their size and surface characteristics.

3

Funding Rounds

$33.0m

Money raised

CoreTigo develops secured wireless network system to support IoT nodes at a latency of milliseconds.

1

Funding Rounds

$750.0k

Money raised

Nutshell is an Ann Arbor, Michigan-based company founded in 2009 by Guy Suter, Andy Fowler and Ian Berry.

1

Funding Rounds

$120.0k

Money raised

Fathom Drone is a Michigan-based drone company founded.

1

Funding Rounds

$2.0m

Money raised

Forever Labs is a stem cells storage company founded in 2015 by Michael Elfassy, Benjamin Buller and Steven Clausnitzer.

2

Funding Rounds

$10.9m

Money raised

AaDya provide smart, simple, affordable and effective cybersecurity software solutions for small and medium businesses.

1

Funding Rounds

$5.0m

Money raised

Billy is a company making smart home technologies to help seniors live independently.

2

Funding Rounds

$3.3m

Money raised

Voxel51 is an artificial Intelligence company founded in 2016 by Jason Corso.

1

Funding Rounds

$250.0k

Money raised

SensiGen is a company developing and commercializing gene-based molecular diagnostic tests for the early detection of diseases.

1

Funding Rounds

$4.2m

Money raised

Refraction AI is a robotic-enabled delivery technology company and manufacturer.

3

Funding Rounds

$2.6m

Money raised

Arbor Photonics is an Ann Arbor, Michigan-based company founded by Almantas Galvanauskas.

1

Funding Rounds

$1.0m

Money raised

Ecovia Renewables is a polyglutamic acid production company founded in 2014.

1

Funding Rounds

$9.4m

Money raised

A company offering an electric unmanned aircraft for first responder surveillance.

3

Funding Rounds

$35.0m

Money raised

Zecco is a company founded in 1919.

2

Funding Rounds

$5.5m

Money raised

Rubicon Genomics is a company that develops nucleic acid library preparation and companion products for the analysis of clinical research samples

2

Funding Rounds

$3.0m

Money raised

Biotectix focuses on the development of bioactive conductive polymer electrodes and coatings for electrodes for medical devices.

2

Funding Rounds

$6.0m

Money raised

Tetra Therapeutics is a Grand Rapids, Michigan-based biotechnology company developing drugs for brain-related diseases.

3

Funding Rounds

$159.3m

Money raised

A medical device company developing surgical renal denervation for the treatment of hypertension

5

Funding Rounds

$47.1m

Money raised

Airspace Link creates drone and air logistic tools to support regulated state & local government airspace management.

Industries:

Location:

5

Funding Rounds

$334.0m

Money raised

PROGENITY, INC is a provider of specialized genetic testing services.

1

Funding Rounds

$5.0m

Money raised

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